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The map label for this gene is serB [C]

Identifier: 116328118

GI number: 116328118

Start: 1649457

End: 1650338

Strand: Direct

Name: serB [C]

Synonym: LBL_1416

Alternate gene names: 116328118

Gene position: 1649457-1650338 (Clockwise)

Preceding gene: 116328117

Following gene: 116328121

Centisome position: 45.64

GC content: 38.89

Gene sequence:

>882_bases
TTGCTTCTCATTCTTACACAAAAACCTTATGAAATTCGAAAAGAACTTCTACTGGGAATCGGAAATTTCGTATCCCTCAA
ATCCGAAGAAACTTTTTTACTTTCTTCGGCCTCGGTTCGTACTCAAGGAGAATGGAGCTGCATCGAATGGAAAATTTCCA
GAAATTTGGATTTGCAGGAGTTGATCGAACTGAGAGCAATGTTTGCAAAAAGAAATTCGGATCTTCTTCAGATAGATTAT
CTTTTAGATCCAAAGAAAAAAAGTTTTTTCGTTTTTGATATGGACTCTACTTTGATCCAGCAAGAAGTCATCGACGAGTT
AGCGAGGCTTACGGGAGTTTACGAAGAAGTCGCTTCTGTCACGAAGGAGGCAATGGAAGGAAATTTGGACTTTCATGAAG
CTCTTAAAAAAAGATGTGTTCACTTAAAAGGGCTTTCCTCCTCCATTTTTACGGAGCTTTATCCAAAACTAAAATTGAAT
GCAGGGGTCGAAAGTCTTCTGAGAAGTTTGAAAGAGAAAAATAGTAAGACCGCGGTGTTTTCGGGAGGTTTTATAGACAT
TTTGGAAATGTTCCAGAAGCAGTATGGAATCGATGAAATTCACGCGAACGTTTTAGAAAGACAAAACGGTCAATTTTCGG
GGAATGTGGTCGGTGATATCGTTGATAAAAATAAAAAATTTGAATATTTAAAGATGATTCGGGATCGGGAGGGAATTTCC
AGATCTCAAGTGGTTGCTGTCGGAGACGGAGCAAACGATGCATTGATGTTAAACGAAGCGGGGCTTGGAATCGGGTTTCA
TGCAAAAGAGGGCTTGAAAAAACTCATCGTCAATTGGGTGGATTTTGCTCCGTTAGATGTTCTTCTATTTTTGTTTTCTT
AA

Upstream 100 bases:

>100_bases
GGCTCGAACGAGACGAGATCCACTTGAACGAAAATGCATACAAGGTTTGGGTTGAAAAATTAAAACCGATCCTTTTACCT
TATCTCTAAAAGGTTTCCCT

Downstream 100 bases:

>100_bases
TTTTTTTTGAAAATCCTCTAGTTTTTTTAAGGCTTCCATTGGAGTCATTTCTTCCAGTTTCAATTTTAGAATGGATTCTT
CCGTTTCAGACGGGAGATTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLLILTQKPYEIRKELLLGIGNFVSLKSEETFLLSSASVRTQGEWSCIEWKISRNLDLQELIELRAMFAKRNSDLLQIDY
LLDPKKKSFFVFDMDSTLIQQEVIDELARLTGVYEEVASVTKEAMEGNLDFHEALKKRCVHLKGLSSSIFTELYPKLKLN
AGVESLLRSLKEKNSKTAVFSGGFIDILEMFQKQYGIDEIHANVLERQNGQFSGNVVGDIVDKNKKFEYLKMIRDREGIS
RSQVVAVGDGANDALMLNEAGLGIGFHAKEGLKKLIVNWVDFAPLDVLLFLFS

Sequences:

>Translated_293_residues
MLLILTQKPYEIRKELLLGIGNFVSLKSEETFLLSSASVRTQGEWSCIEWKISRNLDLQELIELRAMFAKRNSDLLQIDY
LLDPKKKSFFVFDMDSTLIQQEVIDELARLTGVYEEVASVTKEAMEGNLDFHEALKKRCVHLKGLSSSIFTELYPKLKLN
AGVESLLRSLKEKNSKTAVFSGGFIDILEMFQKQYGIDEIHANVLERQNGQFSGNVVGDIVDKNKKFEYLKMIRDREGIS
RSQVVAVGDGANDALMLNEAGLGIGFHAKEGLKKLIVNWVDFAPLDVLLFLFS
>Mature_293_residues
MLLILTQKPYEIRKELLLGIGNFVSLKSEETFLLSSASVRTQGEWSCIEWKISRNLDLQELIELRAMFAKRNSDLLQIDY
LLDPKKKSFFVFDMDSTLIQQEVIDELARLTGVYEEVASVTKEAMEGNLDFHEALKKRCVHLKGLSSSIFTELYPKLKLN
AGVESLLRSLKEKNSKTAVFSGGFIDILEMFQKQYGIDEIHANVLERQNGQFSGNVVGDIVDKNKKFEYLKMIRDREGIS
RSQVVAVGDGANDALMLNEAGLGIGFHAKEGLKKLIVNWVDFAPLDVLLFLFS

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790849, Length=198, Percent_Identity=41.9191919191919, Blast_Score=147, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI115534454, Length=200, Percent_Identity=32.5, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534456, Length=200, Percent_Identity=32.5, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=202, Percent_Identity=32.1782178217822, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=192, Percent_Identity=40.625, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24661601, Length=188, Percent_Identity=31.3829787234043, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 33164; Mature: 33164

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLILTQKPYEIRKELLLGIGNFVSLKSEETFLLSSASVRTQGEWSCIEWKISRNLDLQE
CEEEEECCCHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCHHH
LIELRAMFAKRNSDLLQIDYLLDPKKKSFFVFDMDSTLIQQEVIDELARLTGVYEEVASV
HHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
TKEAMEGNLDFHEALKKRCVHLKGLSSSIFTELYPKLKLNAGVESLLRSLKEKNSKTAVF
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCEEEE
SGGFIDILEMFQKQYGIDEIHANVLERQNGQFSGNVVGDIVDKNKKFEYLKMIRDREGIS
ECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCC
RSQVVAVGDGANDALMLNEAGLGIGFHAKEGLKKLIVNWVDFAPLDVLLFLFS
CCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MLLILTQKPYEIRKELLLGIGNFVSLKSEETFLLSSASVRTQGEWSCIEWKISRNLDLQE
CEEEEECCCHHHHHHHHHHCCCCEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCHHH
LIELRAMFAKRNSDLLQIDYLLDPKKKSFFVFDMDSTLIQQEVIDELARLTGVYEEVASV
HHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
TKEAMEGNLDFHEALKKRCVHLKGLSSSIFTELYPKLKLNAGVESLLRSLKEKNSKTAVF
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCEEEE
SGGFIDILEMFQKQYGIDEIHANVLERQNGQFSGNVVGDIVDKNKKFEYLKMIRDREGIS
ECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCC
RSQVVAVGDGANDALMLNEAGLGIGFHAKEGLKKLIVNWVDFAPLDVLLFLFS
CCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]