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The map label for this gene is aatA [H]

Identifier: 116328104

GI number: 116328104

Start: 1634862

End: 1636079

Strand: Direct

Name: aatA [H]

Synonym: LBL_1402

Alternate gene names: 116328104

Gene position: 1634862-1636079 (Clockwise)

Preceding gene: 116328103

Following gene: 116328105

Centisome position: 45.23

GC content: 44.01

Gene sequence:

>1218_bases
ATGGATCTCAGCGCAAAAAGGCTGAATGTCATCGAACCTTCTCCCACGCTCGTAATTACCGCCAAGGCGAACGAGTTGAA
AAAAAAGGGAGAAGATATTGTCAGTTTCGGAGCTGGAGAGCCCGATTTCGAAACTCCGTCCCATATCAGAGATGCCGCAA
AGAAAGCGATTGATAAGGGGGTGACCCGTTATACGGCTGTTTCTGGAACGGTTGAACTTAAGGAGGCCATCGTTCACAAA
TTCAAAAGAGATAACGGACTTGATTACGAAAAAAACCAAGTCATCGCCGGAACGGGTGGAAAACAAGTTATCTACAATTA
TTTTCTGGCGACTTTAAATACGGGAGATGAAGTCATTATTCCGGCGCCGTATTGGGTCAGTTATGCGGATATCGTTCGTT
TGTCGGAGGGTGTTCCTGTGATCGTTACCACTACCCCGGAAAATAACTTTCAAATCACTCCGGAACAATTGAAGAAGGTG
ATCACTCCTAAGACAAAATGTTTGATTTTAAATTCCCCTTCCAATCCGACGGGGGCTGGTTATTCTAAAAAGGATTTGGA
AGTTTTGGGGGAAATCGTACTTTCTGCCGGAATTCAGGTGATGAGCGACGATATCTATGAAAAGATCGTCTACGACGGAT
TTACGTTTTCCAATCTTGCGATGTTGTCTCCCGAACTTAAAAAACGGACTTTTATCGTAAACGGGGTTTCTAAAACCTAT
TCCATGACCGGCTGGAGAATCGGCTATGGGGCCGGGGATATAGGAATCGTTAAGAATATGGAAACGATTCAAAGTCAGTC
TACTTCTAATCCTTCTTCGATTTCTCAAGCGGCAGCGGAAGCGGCGATTGCAGGGGATCAGGTTTGTGTGGAAGAGATGA
GAAAAGCGTTTGAAGCGAGAAGAAATCTGATCGTTTCCCTTTTAAATTCAATCCCTGGTGTGAAATGTAATCGTCCGCAG
GGTGCGTTTTACGTTTTCCCATATCTCACGGATGTGTATAAAACTCCGGGTTTTGAAAAACTGAAAAAGGAAACTTCTGA
AACGTCCTTGAGTAAAATCTTCTGCAGTGTTCTATTAGAAAAATATAAAGTAGCAGGAGTTCCCGGGATCGCTTTCGGAG
AAGATAAAGCTCTTAGACTTTCCTATGCGATGGGTGAAGCGGATATAAGACGCGGGGTCGAAAGAATCGCGGAAATGATA
CGGGATCTGAGCAAATAA

Upstream 100 bases:

>100_bases
AAGAATTAGCTCAATTGCAACTGAATAATGTTTGATTCTTTTTTGTTAGAATTGGTCGGAAAAAAACGGATCGAAGTTAA
AATATAAAAAGGGGAACAGA

Downstream 100 bases:

>100_bases
ACAATGAGACGGATCGTTTTGGTCCTCATCTTTTTTATGGCTGTCCCGTACATTTTTGGGGGTGATCGTTTGGTTCTTAA
GCCGAGTTCTCCCCTCTATT

Product: aspartate/tyrosine/aromatic aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKKAIDKGVTRYTAVSGTVELKEAIVHK
FKRDNGLDYEKNQVIAGTGGKQVIYNYFLATLNTGDEVIIPAPYWVSYADIVRLSEGVPVIVTTTPENNFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYSKKDLEVLGEIVLSAGIQVMSDDIYEKIVYDGFTFSNLAMLSPELKKRTFIVNGVSKTY
SMTGWRIGYGAGDIGIVKNMETIQSQSTSNPSSISQAAAEAAIAGDQVCVEEMRKAFEARRNLIVSLLNSIPGVKCNRPQ
GAFYVFPYLTDVYKTPGFEKLKKETSETSLSKIFCSVLLEKYKVAGVPGIAFGEDKALRLSYAMGEADIRRGVERIAEMI
RDLSK

Sequences:

>Translated_405_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKKAIDKGVTRYTAVSGTVELKEAIVHK
FKRDNGLDYEKNQVIAGTGGKQVIYNYFLATLNTGDEVIIPAPYWVSYADIVRLSEGVPVIVTTTPENNFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYSKKDLEVLGEIVLSAGIQVMSDDIYEKIVYDGFTFSNLAMLSPELKKRTFIVNGVSKTY
SMTGWRIGYGAGDIGIVKNMETIQSQSTSNPSSISQAAAEAAIAGDQVCVEEMRKAFEARRNLIVSLLNSIPGVKCNRPQ
GAFYVFPYLTDVYKTPGFEKLKKETSETSLSKIFCSVLLEKYKVAGVPGIAFGEDKALRLSYAMGEADIRRGVERIAEMI
RDLSK
>Mature_405_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKKAIDKGVTRYTAVSGTVELKEAIVHK
FKRDNGLDYEKNQVIAGTGGKQVIYNYFLATLNTGDEVIIPAPYWVSYADIVRLSEGVPVIVTTTPENNFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYSKKDLEVLGEIVLSAGIQVMSDDIYEKIVYDGFTFSNLAMLSPELKKRTFIVNGVSKTY
SMTGWRIGYGAGDIGIVKNMETIQSQSTSNPSSISQAAAEAAIAGDQVCVEEMRKAFEARRNLIVSLLNSIPGVKCNRPQ
GAFYVFPYLTDVYKTPGFEKLKKETSETSLSKIFCSVLLEKYKVAGVPGIAFGEDKALRLSYAMGEADIRRGVERIAEMI
RDLSK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=349, Percent_Identity=28.080229226361, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI169881279, Length=349, Percent_Identity=28.080229226361, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI56713254, Length=312, Percent_Identity=26.2820512820513, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI56713256, Length=312, Percent_Identity=26.2820512820513, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI169881281, Length=346, Percent_Identity=26.5895953757225, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=25.6476683937824, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI19263340, Length=372, Percent_Identity=22.3118279569892, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=22.3118279569892, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1788722, Length=415, Percent_Identity=29.1566265060241, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=24.1286863270777, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788627, Length=321, Percent_Identity=28.9719626168224, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787909, Length=389, Percent_Identity=21.5938303341902, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=344, Percent_Identity=26.453488372093, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=264, Percent_Identity=28.7878787878788, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=264, Percent_Identity=28.7878787878788, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=260, Percent_Identity=27.6923076923077, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=400, Percent_Identity=24.25, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573069, Length=359, Percent_Identity=24.5125348189415, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646114, Length=359, Percent_Identity=24.5125348189415, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573067, Length=359, Percent_Identity=24.5125348189415, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573065, Length=359, Percent_Identity=24.5125348189415, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI18859735, Length=192, Percent_Identity=26.0416666666667, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44352; Mature: 44352

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKKAIDKG
CCCCCCCCEEECCCCCEEEEECHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHC
VTRYTAVSGTVELKEAIVHKFKRDNGLDYEKNQVIAGTGGKQVIYNYFLATLNTGDEVII
CHHEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLSEGVPVIVTTTPENNFQITPEQLKKVITPKTKCLILNSPSNPTGAG
CCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCC
YSKKDLEVLGEIVLSAGIQVMSDDIYEKIVYDGFTFSNLAMLSPELKKRTFIVNGVSKTY
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHCEEEEECCCHHE
SMTGWRIGYGAGDIGIVKNMETIQSQSTSNPSSISQAAAEAAIAGDQVCVEEMRKAFEAR
ECCCEEEECCCCCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RNLIVSLLNSIPGVKCNRPQGAFYVFPYLTDVYKTPGFEKLKKETSETSLSKIFCSVLLE
HHHHHHHHHHCCCCEECCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYKVAGVPGIAFGEDKALRLSYAMGEADIRRGVERIAEMIRDLSK
HHHHCCCCCEEECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKKAIDKG
CCCCCCCCEEECCCCCEEEEECHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHC
VTRYTAVSGTVELKEAIVHKFKRDNGLDYEKNQVIAGTGGKQVIYNYFLATLNTGDEVII
CHHEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLSEGVPVIVTTTPENNFQITPEQLKKVITPKTKCLILNSPSNPTGAG
CCCHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCC
YSKKDLEVLGEIVLSAGIQVMSDDIYEKIVYDGFTFSNLAMLSPELKKRTFIVNGVSKTY
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHCEEEEECCCHHE
SMTGWRIGYGAGDIGIVKNMETIQSQSTSNPSSISQAAAEAAIAGDQVCVEEMRKAFEAR
ECCCEEEECCCCCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RNLIVSLLNSIPGVKCNRPQGAFYVFPYLTDVYKTPGFEKLKKETSETSLSKIFCSVLLE
HHHHHHHHHHCCCCEECCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYKVAGVPGIAFGEDKALRLSYAMGEADIRRGVERIAEMIRDLSK
HHHHCCCCCEEECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA