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The map label for this gene is argS

Identifier: 116327967

GI number: 116327967

Start: 1477631

End: 1479391

Strand: Direct

Name: argS

Synonym: LBL_1256

Alternate gene names: 116327967

Gene position: 1477631-1479391 (Clockwise)

Preceding gene: 116327966

Following gene: 116327968

Centisome position: 40.88

GC content: 41.91

Gene sequence:

>1761_bases
ATGAAAGAAAATGAAACACTCAAACAAATCGTATTAAAATCACTGGAAGAAGGAGTGGATTCCTTAATTGTTTCGTTTCC
GGATGTGGAAAAAAGTTCGCTCCGAATAAAAATCGAATATTCCAGAGATGAAAAATTTGGAGATTATTCCACGTCATTTT
CATTAGAAAATTCTAAATTACTAAAAAGAAATCCGATTCAAGTATCGAAAGAACTAGTGGAAATTCTGCAAAAACGGACC
GATCTTTTCGAGAAAGTGGATTTTACCCCTCCCGGCTTCGTAAATTTCAAAATTTCCCCATCGTATCTTTTGGAATACAT
AGAAAAGTCCATTCTTTCCGGAGATCATTTCCCAAAAGTGGAACACCCTCTCAAGATTAACTTAGAATTCGTATCCGCAA
ATCCGACAGGTCCGCTCAATATAGTTTCTGCACGGGCCGCGGCGAACGGAGACACGATGGCTTCTCTTCTAAAGGCGATC
GGTCATAATGTGGACAAGGAATTTTACATCAACGATTACGGAAATCAGGTTTTTTTACTCGGAGTTTCCACTTTGGTTCG
GATCCGAGAAATAAAGGGAGAATTCAGCACCCGGCAAGAAGCGGACGATACTACACCGATAGATACGATTTTGGAAAAGA
ATATATTACCGGCCGAGGGTTATCGAGGCGAATATATAAAGGATATTGCAAATGCTCTTTTAAATGAACCGAAAAAATCC
TCTCAGATTGAAACGTTGTTAAAAGAAAAAAAATACCGTGAACTCGCGGAGCTTTGTTCTATCTGGACCGTGGAGAACAA
TCTTGATTGGCAGAGAAAGGATTTGGACTCGTTCGGAGTTGAGTTCGATAATTACTTCCGTGAACGGACACTTCACGAAT
CGGATAAGGTTCTTGCGGTGATGAAAGATTTGGAAAGAGTCGGAAAAATCTTTGAAGAAGACGGAAAAAAAATATTTCGA
TCTACGGAATACGGAGACGACAAGGATCGGGTCGTGGTTCGAGACGACGGAAGACCGACGTATCTACTCGCGGATATCGC
TTATCATAAGGATAAAATCGAGCGTGGATACGATAGAATCTACGATATCTGGGGACCGGATCATCATGGTTATATCTCGA
GACTTTCCGGAGCGGTACAAACTCTTGGATATAAAAAGGAAAATTTTAAAGTAATTATTTCTCAACAAGTCAATCTACTC
GAATCGGGACAAAAGGTAAAAATGAGTAAACGTGCCGGTTCCTTTCAAACGATGAGTGATCTCATCGGATTTTTGGGAAA
ACACGGCAAAGACGTAGGACGTTACTTTTTTGTAATGCGTTCCCTGGACGCACCTCTCGATTTTGATTTGGACCTGGCCC
AGGATCAGTCGGATAAAAATCCGGTTTTTTATCTGCAGTATGCGCATGCAAGAATCTGTTCCATCTTTCGAGAGGTGGGA
ACGGAAAGTTCCGCCGAAGCGGCCGAATCTTTGGAGATGTCCGAAGAGCGAAAAAGACTTTTATTTTGGATCGCAAGGTT
TCCTGAGGAAATATTCGACTCTGCAAATTCGATGGAACCGCATCGGGTCGCCAATTATCTACAAAGTTTTGCGAAGGCCT
TTACGGGTTTTTATTTAGGAAAGAATAATAGACTGAAAGACGCTACGCCCGAGGTACGTCTTGGACTTGCAAGAATTTGT
CTTGCGGCCAGGAGCGTGCTTGCGGAAGGACTTGGGTTGATCGGTGTTTCCGCTCCCGAAAAAATGGAAAAGGAAAGTTA
A

Upstream 100 bases:

>100_bases
AATATGCAGTAGTTCCCACATTTTGCGAAAAATCACTCATCTCAGTTATGCAGAGAGTCTTCTATAAACTCAATCTCGCT
CTCTATGGATCGCTCGACAT

Downstream 100 bases:

>100_bases
TGTCTTTTCCTAAAGTTATCGTAGTGTCTACGGGTTCGGAACTTACTGCAGGAAGAAGTCAGGATACAAATTCCTCCTGG
ATTGCAAACGAACTCTTTGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MKENETLKQIVLKSLEEGVDSLIVSFPDVEKSSLRIKIEYSRDEKFGDYSTSFSLENSKLLKRNPIQVSKELVEILQKRT
DLFEKVDFTPPGFVNFKISPSYLLEYIEKSILSGDHFPKVEHPLKINLEFVSANPTGPLNIVSARAAANGDTMASLLKAI
GHNVDKEFYINDYGNQVFLLGVSTLVRIREIKGEFSTRQEADDTTPIDTILEKNILPAEGYRGEYIKDIANALLNEPKKS
SQIETLLKEKKYRELAELCSIWTVENNLDWQRKDLDSFGVEFDNYFRERTLHESDKVLAVMKDLERVGKIFEEDGKKIFR
STEYGDDKDRVVVRDDGRPTYLLADIAYHKDKIERGYDRIYDIWGPDHHGYISRLSGAVQTLGYKKENFKVIISQQVNLL
ESGQKVKMSKRAGSFQTMSDLIGFLGKHGKDVGRYFFVMRSLDAPLDFDLDLAQDQSDKNPVFYLQYAHARICSIFREVG
TESSAEAAESLEMSEERKRLLFWIARFPEEIFDSANSMEPHRVANYLQSFAKAFTGFYLGKNNRLKDATPEVRLGLARIC
LAARSVLAEGLGLIGVSAPEKMEKES

Sequences:

>Translated_586_residues
MKENETLKQIVLKSLEEGVDSLIVSFPDVEKSSLRIKIEYSRDEKFGDYSTSFSLENSKLLKRNPIQVSKELVEILQKRT
DLFEKVDFTPPGFVNFKISPSYLLEYIEKSILSGDHFPKVEHPLKINLEFVSANPTGPLNIVSARAAANGDTMASLLKAI
GHNVDKEFYINDYGNQVFLLGVSTLVRIREIKGEFSTRQEADDTTPIDTILEKNILPAEGYRGEYIKDIANALLNEPKKS
SQIETLLKEKKYRELAELCSIWTVENNLDWQRKDLDSFGVEFDNYFRERTLHESDKVLAVMKDLERVGKIFEEDGKKIFR
STEYGDDKDRVVVRDDGRPTYLLADIAYHKDKIERGYDRIYDIWGPDHHGYISRLSGAVQTLGYKKENFKVIISQQVNLL
ESGQKVKMSKRAGSFQTMSDLIGFLGKHGKDVGRYFFVMRSLDAPLDFDLDLAQDQSDKNPVFYLQYAHARICSIFREVG
TESSAEAAESLEMSEERKRLLFWIARFPEEIFDSANSMEPHRVANYLQSFAKAFTGFYLGKNNRLKDATPEVRLGLARIC
LAARSVLAEGLGLIGVSAPEKMEKES
>Mature_586_residues
MKENETLKQIVLKSLEEGVDSLIVSFPDVEKSSLRIKIEYSRDEKFGDYSTSFSLENSKLLKRNPIQVSKELVEILQKRT
DLFEKVDFTPPGFVNFKISPSYLLEYIEKSILSGDHFPKVEHPLKINLEFVSANPTGPLNIVSARAAANGDTMASLLKAI
GHNVDKEFYINDYGNQVFLLGVSTLVRIREIKGEFSTRQEADDTTPIDTILEKNILPAEGYRGEYIKDIANALLNEPKKS
SQIETLLKEKKYRELAELCSIWTVENNLDWQRKDLDSFGVEFDNYFRERTLHESDKVLAVMKDLERVGKIFEEDGKKIFR
STEYGDDKDRVVVRDDGRPTYLLADIAYHKDKIERGYDRIYDIWGPDHHGYISRLSGAVQTLGYKKENFKVIISQQVNLL
ESGQKVKMSKRAGSFQTMSDLIGFLGKHGKDVGRYFFVMRSLDAPLDFDLDLAQDQSDKNPVFYLQYAHARICSIFREVG
TESSAEAAESLEMSEERKRLLFWIARFPEEIFDSANSMEPHRVANYLQSFAKAFTGFYLGKNNRLKDATPEVRLGLARIC
LAARSVLAEGLGLIGVSAPEKMEKES

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=602, Percent_Identity=22.093023255814, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985061, Length=599, Percent_Identity=22.3706176961603, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71985068, Length=551, Percent_Identity=22.6860254083485, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_LEPBJ (Q04TG2)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800566.1
- ProteinModelPortal:   Q04TG2
- STRING:   Q04TG2
- GeneID:   4411150
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1204
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   LBOR355277:LBJ_1204-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 66834; Mature: 66834

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENETLKQIVLKSLEEGVDSLIVSFPDVEKSSLRIKIEYSRDEKFGDYSTSFSLENSKL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCHH
LKRNPIQVSKELVEILQKRTDLFEKVDFTPPGFVNFKISPSYLLEYIEKSILSGDHFPKV
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCC
EHPLKINLEFVSANPTGPLNIVSARAAANGDTMASLLKAIGHNVDKEFYINDYGNQVFLL
CCCEEEEEEEEECCCCCCCEEEEHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEE
GVSTLVRIREIKGEFSTRQEADDTTPIDTILEKNILPAEGYRGEYIKDIANALLNEPKKS
EHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCH
SQIETLLKEKKYRELAELCSIWTVENNLDWQRKDLDSFGVEFDNYFRERTLHESDKVLAV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHH
MKDLERVGKIFEEDGKKIFRSTEYGDDKDRVVVRDDGRPTYLLADIAYHKDKIERGYDRI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
YDIWGPDHHGYISRLSGAVQTLGYKKENFKVIISQQVNLLESGQKVKMSKRAGSFQTMSD
EECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCEEHHHHCCCHHHHHH
LIGFLGKHGKDVGRYFFVMRSLDAPLDFDLDLAQDQSDKNPVFYLQYAHARICSIFREVG
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
TESSAEAAESLEMSEERKRLLFWIARFPEEIFDSANSMEPHRVANYLQSFAKAFTGFYLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEC
KNNRLKDATPEVRLGLARICLAARSVLAEGLGLIGVSAPEKMEKES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCC
>Mature Secondary Structure
MKENETLKQIVLKSLEEGVDSLIVSFPDVEKSSLRIKIEYSRDEKFGDYSTSFSLENSKL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCHH
LKRNPIQVSKELVEILQKRTDLFEKVDFTPPGFVNFKISPSYLLEYIEKSILSGDHFPKV
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCC
EHPLKINLEFVSANPTGPLNIVSARAAANGDTMASLLKAIGHNVDKEFYINDYGNQVFLL
CCCEEEEEEEEECCCCCCCEEEEHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEE
GVSTLVRIREIKGEFSTRQEADDTTPIDTILEKNILPAEGYRGEYIKDIANALLNEPKKS
EHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCH
SQIETLLKEKKYRELAELCSIWTVENNLDWQRKDLDSFGVEFDNYFRERTLHESDKVLAV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHH
MKDLERVGKIFEEDGKKIFRSTEYGDDKDRVVVRDDGRPTYLLADIAYHKDKIERGYDRI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
YDIWGPDHHGYISRLSGAVQTLGYKKENFKVIISQQVNLLESGQKVKMSKRAGSFQTMSD
EECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCEEHHHHCCCHHHHHH
LIGFLGKHGKDVGRYFFVMRSLDAPLDFDLDLAQDQSDKNPVFYLQYAHARICSIFREVG
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
TESSAEAAESLEMSEERKRLLFWIARFPEEIFDSANSMEPHRVANYLQSFAKAFTGFYLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEC
KNNRLKDATPEVRLGLARICLAARSVLAEGLGLIGVSAPEKMEKES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA