Click here to switch to the map view.

The map label for this gene is cyaA [H]

Identifier: 116327833

GI number: 116327833

Start: 1304308

End: 1305744

Strand: Reverse

Name: cyaA [H]

Synonym: LBL_1109

Alternate gene names: 116327833

Gene position: 1305744-1304308 (Counterclockwise)

Preceding gene: 116327835

Following gene: 116327832

Centisome position: 36.13

GC content: 39.39

Gene sequence:

>1437_bases
ATGCATTTCTCCCTTTTTTATAAAAGAATTTTTTTTAAAATCGATTTCTCTTTCCGGAAAGAATTGATCTATAACCCGGA
AGTTTCTATCTTTAACTTTGTGAATATACTCCTATCGATCAAAAAAGCGCTTCATACATTGGATAGAAAATCCATGCCGG
ATTCCGTTTTGGAAGTTCTCAAAAAAGAAGAAAGAAGCGGAATCATCATCACAAATTACTTTCGCTATCTAATCGCCTTA
TTTTTTCTGGTTCAGATCGTCGTCAACGTCAACAGCGGAAACTACAAATTCAATCTCGCCGCGTTTTCGATCTATCTTGG
TTTAACGTTCGCGCATACGATCATCATTCGAATTTCTCCCCTTTCCATAGTAAGCGTTTTCAATTACGTTACTTTGTTCG
CCGAGTACGCCCTTATACTCGGAGTTTTACTTTTTTACACCTTCACTACGGAAAACGTGGATTTAGGTTTCGCTCTGAAG
AATCCGATAAATCTCTTCTTTTTATTCCCGATTGTCTATTCCCTTTTGCAATTTAAAATCCGTTTCGTCTTTATTGGACT
ATTTCTATTTTATTTAATTTATTATTCGATTTTATGGATTGCGATTTCTCAAAATCAACTCGTATATACGAAGGATTGGG
GACGTTATGTCAGTGGTCCGAATATTTTGGTCGAAGATATAGTCGCGGGCAAACCAGGTTTGTATTTTTGTTTCGCGATG
ATGATTTCCACGGGAATTTTCCGGACAATCTCGATGGTCAAAAGAATCGGAATTGTAGAAGGTCAAAAGACCGAACTCTC
CAGATATTTTTCACCTAAGATCGTAAACGAAATGGTGGAAAATCCGGAAACTTTTCAAAACGGAAATCGACAAATCGTAA
GTATCCTTTTTTTAGACATTCGCAACTTTACCTCCATGTCCGAGAGCATGGATCCGAAAGAACTCGGCGAACTTCTATCG
GAATTTCGGAAGATAATGACGGAATGTGTCTTTGAAAACAATGGAACCTTGGATAAATATATCGGCGATGCCGTGATGGC
GACATTCGGCACACCTCGCCCTTCTCCTTCGGCGGAAGTAGATGCAAGAAATGCGGTCGGCTGCGGAGTTATTATGCAAA
AACGTCTCTCCGAATGGAATTTACTACGAAAATCGGAAGGAAAAGTCCCGATCTCTATCGGTATAGGAATTCATACGGGA
GAAGTTTTTGCAGGAAACGTAGGAAGCGATCTTCACAGAGAATATTCGGTCATCGGAGACGCAGTCAACACCGCTTCTCG
TATCGAATCTCTTTGTAAGATTTTGAAAAAACCTTTTCTTATTTCGAAAGAAACCATGGAGCTGTTAGGTGGAAAATATA
CTCTCAATCGTATGCCCCGTGTCAAAGTCAAAGGGAAAGAAGAACCACTTCAAATCTACGAAGTTGTTTGGGGTTAA

Upstream 100 bases:

>100_bases
ATAATTCCTCCAAAAGATATTTTCCGATCAAACCCGTCGCACCTGCGACTAACGCTAATTTCTGAGCCATAATTACTCTC
TCCTACAAAATGCAAAAAGA

Downstream 100 bases:

>100_bases
TTCACGACCCATAGGTCAATGCTGTCAATTTAAGAAAAAAGACTAAAGATTAAAGAATTTAGTACGACAAGAAGACATGG
GCAAGAAAGAATTACAATCA

Product: adenylate cyclase-like protein

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MHFSLFYKRIFFKIDFSFRKELIYNPEVSIFNFVNILLSIKKALHTLDRKSMPDSVLEVLKKEERSGIIITNYFRYLIAL
FFLVQIVVNVNSGNYKFNLAAFSIYLGLTFAHTIIIRISPLSIVSVFNYVTLFAEYALILGVLLFYTFTTENVDLGFALK
NPINLFFLFPIVYSLLQFKIRFVFIGLFLFYLIYYSILWIAISQNQLVYTKDWGRYVSGPNILVEDIVAGKPGLYFCFAM
MISTGIFRTISMVKRIGIVEGQKTELSRYFSPKIVNEMVENPETFQNGNRQIVSILFLDIRNFTSMSESMDPKELGELLS
EFRKIMTECVFENNGTLDKYIGDAVMATFGTPRPSPSAEVDARNAVGCGVIMQKRLSEWNLLRKSEGKVPISIGIGIHTG
EVFAGNVGSDLHREYSVIGDAVNTASRIESLCKILKKPFLISKETMELLGGKYTLNRMPRVKVKGKEEPLQIYEVVWG

Sequences:

>Translated_478_residues
MHFSLFYKRIFFKIDFSFRKELIYNPEVSIFNFVNILLSIKKALHTLDRKSMPDSVLEVLKKEERSGIIITNYFRYLIAL
FFLVQIVVNVNSGNYKFNLAAFSIYLGLTFAHTIIIRISPLSIVSVFNYVTLFAEYALILGVLLFYTFTTENVDLGFALK
NPINLFFLFPIVYSLLQFKIRFVFIGLFLFYLIYYSILWIAISQNQLVYTKDWGRYVSGPNILVEDIVAGKPGLYFCFAM
MISTGIFRTISMVKRIGIVEGQKTELSRYFSPKIVNEMVENPETFQNGNRQIVSILFLDIRNFTSMSESMDPKELGELLS
EFRKIMTECVFENNGTLDKYIGDAVMATFGTPRPSPSAEVDARNAVGCGVIMQKRLSEWNLLRKSEGKVPISIGIGIHTG
EVFAGNVGSDLHREYSVIGDAVNTASRIESLCKILKKPFLISKETMELLGGKYTLNRMPRVKVKGKEEPLQIYEVVWG
>Mature_478_residues
MHFSLFYKRIFFKIDFSFRKELIYNPEVSIFNFVNILLSIKKALHTLDRKSMPDSVLEVLKKEERSGIIITNYFRYLIAL
FFLVQIVVNVNSGNYKFNLAAFSIYLGLTFAHTIIIRISPLSIVSVFNYVTLFAEYALILGVLLFYTFTTENVDLGFALK
NPINLFFLFPIVYSLLQFKIRFVFIGLFLFYLIYYSILWIAISQNQLVYTKDWGRYVSGPNILVEDIVAGKPGLYFCFAM
MISTGIFRTISMVKRIGIVEGQKTELSRYFSPKIVNEMVENPETFQNGNRQIVSILFLDIRNFTSMSESMDPKELGELLS
EFRKIMTECVFENNGTLDKYIGDAVMATFGTPRPSPSAEVDARNAVGCGVIMQKRLSEWNLLRKSEGKVPISIGIGIHTG
EVFAGNVGSDLHREYSVIGDAVNTASRIESLCKILKKPFLISKETMELLGGKYTLNRMPRVKVKGKEEPLQIYEVVWG

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Homo sapiens, GI134152694, Length=216, Percent_Identity=30.0925925925926, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86564713, Length=222, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62484298, Length=175, Percent_Identity=34.2857142857143, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI62484477, Length=175, Percent_Identity=34.2857142857143, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI116008008, Length=175, Percent_Identity=34.2857142857143, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161078020, Length=216, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330468, Length=224, Percent_Identity=31.6964285714286, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330470, Length=224, Percent_Identity=31.6964285714286, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 54630; Mature: 54630

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFSLFYKRIFFKIDFSFRKELIYNPEVSIFNFVNILLSIKKALHTLDRKSMPDSVLEVL
CCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KKEERSGIIITNYFRYLIALFFLVQIVVNVNSGNYKFNLAAFSIYLGLTFAHTIIIRISP
HHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHEEEEEECH
LSIVSVFNYVTLFAEYALILGVLLFYTFTTENVDLGFALKNPINLFFLFPIVYSLLQFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
RFVFIGLFLFYLIYYSILWIAISQNQLVYTKDWGRYVSGPNILVEDIVAGKPGLYFCFAM
HHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHH
MISTGIFRTISMVKRIGIVEGQKTELSRYFSPKIVNEMVENPETFQNGNRQIVSILFLDI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
RNFTSMSESMDPKELGELLSEFRKIMTECVFENNGTLDKYIGDAVMATFGTPRPSPSAEV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DARNAVGCGVIMQKRLSEWNLLRKSEGKVPISIGIGIHTGEVFAGNVGSDLHREYSVIGD
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCEEECCCCHHHHHHHHHHHH
AVNTASRIESLCKILKKPFLISKETMELLGGKYTLNRMPRVKVKGKEEPLQIYEVVWG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECCCCEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MHFSLFYKRIFFKIDFSFRKELIYNPEVSIFNFVNILLSIKKALHTLDRKSMPDSVLEVL
CCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KKEERSGIIITNYFRYLIALFFLVQIVVNVNSGNYKFNLAAFSIYLGLTFAHTIIIRISP
HHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHEEEEEECH
LSIVSVFNYVTLFAEYALILGVLLFYTFTTENVDLGFALKNPINLFFLFPIVYSLLQFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
RFVFIGLFLFYLIYYSILWIAISQNQLVYTKDWGRYVSGPNILVEDIVAGKPGLYFCFAM
HHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHH
MISTGIFRTISMVKRIGIVEGQKTELSRYFSPKIVNEMVENPETFQNGNRQIVSILFLDI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHCCCHHHHHHHHHHH
RNFTSMSESMDPKELGELLSEFRKIMTECVFENNGTLDKYIGDAVMATFGTPRPSPSAEV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DARNAVGCGVIMQKRLSEWNLLRKSEGKVPISIGIGIHTGEVFAGNVGSDLHREYSVIGD
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCEEECCCCHHHHHHHHHHHH
AVNTASRIESLCKILKKPFLISKETMELLGGKYTLNRMPRVKVKGKEEPLQIYEVVWG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECCCCEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]