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The map label for this gene is blaR1 [H]

Identifier: 116327814

GI number: 116327814

Start: 1272240

End: 1273070

Strand: Reverse

Name: blaR1 [H]

Synonym: LBL_1082

Alternate gene names: 116327814

Gene position: 1273070-1272240 (Counterclockwise)

Preceding gene: 116327815

Following gene: 116327810

Centisome position: 35.22

GC content: 42.36

Gene sequence:

>831_bases
GTGAAAAGTATCGTCATATCCATCCTCTACGCTCTTTGGCTTTGTTCCTGTAAGAATACCTCTTCCTCAAAATCTTTTTC
CGAAAAGAGTTTAAACGGAAAAGGTAAATTTCTCTGCGCAATCTTAATCAATCAAACGGCGAACGACAAAATTTACTTTC
AAAAAAACGAATGTTCTTATAAAACGCCCCCCTCTTCCCTATTTCATTCCGTTTTAGCTCTTGTGTCCGTGGAAAGCGGT
TATCTTAAAGCGGATCAGTCTCTTTTTTTCTGGGATAAGACAAGATATCCCTACATTCGTTGGCAGAAAGATCAGAATCT
CAAATCCGCTTTGGAATATTCGGTACACTGGTATTTCGCAAAACTTTGGAACGATATCGGACCGGAAAAAGGAAAATCGC
TTCTGGAGAAAATCGGAACGTTTCAGGTTCCGTTCACTCGAAATTCATTTTGGTTGGACGGCTCTTATACGATCTCACCT
TCGGAATTCGCCGACTTTTTAATCCGACTTCAGGAAACTTCTCCACCTTTTCGTAAAAAGACGATTCAAACCGTTTTCGA
TCTTTTCAAAAGAATACCCGGCACTCTTTCGAATGCGAGCGGGAGTCACGATCTTGCGGGAGATTGGAACGGAGTGGAAG
ATTATAGATCGGATTCTGCGTTTTATTATACCCAAGACGAAACCGATTCCTGGTTTTGGGTTTCTTTCCAAAAAACGAAC
GTTCGTTGGTTTCTTCTTACGAGAGTCCGAGTTTTAGGACAACCGACGAGTCCCTTGGAAGCGGCGACACTTGCATCCCA
AATCCTCCGGGAAGAATCCATCGTTCCTTAA

Upstream 100 bases:

>100_bases
TTGGAAAAAAGCGGGAAAAATCTATTTCTTTTTTGTTTATATCCCGGTCGTATTCATTTTAATCGGCATCTCTCTTTGGA
CTTGATTCACTCAATTTCAA

Downstream 100 bases:

>100_bases
TCGATATCTCTGAAAGATCGAGAGATCCCTAAAAATCTGAATGACGAAACCGGAATTCGTTCTTAAAATGCCTCCAAACA
GATGAAAAAAATATCGCTAT

Product: class D beta-lactamase-like protein

Products: substituted beta-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKSIVISILYALWLCSCKNTSSSKSFSEKSLNGKGKFLCAILINQTANDKIYFQKNECSYKTPPSSLFHSVLALVSVESG
YLKADQSLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFAKLWNDIGPEKGKSLLEKIGTFQVPFTRNSFWLDGSYTISP
SEFADFLIRLQETSPPFRKKTIQTVFDLFKRIPGTLSNASGSHDLAGDWNGVEDYRSDSAFYYTQDETDSWFWVSFQKTN
VRWFLLTRVRVLGQPTSPLEAATLASQILREESIVP

Sequences:

>Translated_276_residues
MKSIVISILYALWLCSCKNTSSSKSFSEKSLNGKGKFLCAILINQTANDKIYFQKNECSYKTPPSSLFHSVLALVSVESG
YLKADQSLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFAKLWNDIGPEKGKSLLEKIGTFQVPFTRNSFWLDGSYTISP
SEFADFLIRLQETSPPFRKKTIQTVFDLFKRIPGTLSNASGSHDLAGDWNGVEDYRSDSAFYYTQDETDSWFWVSFQKTN
VRWFLLTRVRVLGQPTSPLEAATLASQILREESIVP
>Mature_276_residues
MKSIVISILYALWLCSCKNTSSSKSFSEKSLNGKGKFLCAILINQTANDKIYFQKNECSYKTPPSSLFHSVLALVSVESG
YLKADQSLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFAKLWNDIGPEKGKSLLEKIGTFQVPFTRNSFWLDGSYTISP
SEFADFLIRLQETSPPFRKKTIQTVFDLFKRIPGTLSNASGSHDLAGDWNGVEDYRSDSAFYYTQDETDSWFWVSFQKTN
VRWFLLTRVRVLGQPTSPLEAATLASQILREESIVP

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 31761; Mature: 31761

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIVISILYALWLCSCKNTSSSKSFSEKSLNGKGKFLCAILINQTANDKIYFQKNECSY
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCC
KTPPSSLFHSVLALVSVESGYLKADQSLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFA
CCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
KLWNDIGPEKGKSLLEKIGTFQVPFTRNSFWLDGSYTISPSEFADFLIRLQETSPPFRKK
HHHHHCCHHHHHHHHHHHCCEECCCCCCCEEECCEEEECHHHHHHHHHHHHCCCCCHHHH
TIQTVFDLFKRIPGTLSNASGSHDLAGDWNGVEDYRSDSAFYYTQDETDSWFWVSFQKTN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEEEEEEECC
VRWFLLTRVRVLGQPTSPLEAATLASQILREESIVP
EEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSIVISILYALWLCSCKNTSSSKSFSEKSLNGKGKFLCAILINQTANDKIYFQKNECSY
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCC
KTPPSSLFHSVLALVSVESGYLKADQSLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFA
CCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
KLWNDIGPEKGKSLLEKIGTFQVPFTRNSFWLDGSYTISPSEFADFLIRLQETSPPFRKK
HHHHHCCHHHHHHHHHHHCCEECCCCCCCEEECCEEEECHHHHHHHHHHHHCCCCCHHHH
TIQTVFDLFKRIPGTLSNASGSHDLAGDWNGVEDYRSDSAFYYTQDETDSWFWVSFQKTN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCEEEEEEEECC
VRWFLLTRVRVLGQPTSPLEAATLASQILREESIVP
EEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]