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The map label for this gene is ruvA

Identifier: 116327800

GI number: 116327800

Start: 1246899

End: 1247537

Strand: Reverse

Name: ruvA

Synonym: LBL_1063

Alternate gene names: 116327800

Gene position: 1247537-1246899 (Counterclockwise)

Preceding gene: 116327801

Following gene: 116327799

Centisome position: 34.52

GC content: 38.03

Gene sequence:

>639_bases
ATGATTTCAGGTTTGAAAGGAACTCTTAAAAAATTAGAAGTCGGATATGCCCACATTGAGACCGGCGGAATCACTTACGA
AGTAACGATCTCTTTCAAAACCTATCTGGAACTCAAAAGTCTTCCGTCCCACAACGAAGTTCAATTTCAAATTTTTCACG
CAATGAATGAAAGGGGTCAGAAACTTTTCGGATTTTTAACCGAACAAGACAAAGAATTTTTCAAGGTCATCAAAGGACTT
CAAGGAATCGGAGAATTGACAGCCCTCAAAATTCTTTCTTTTTTTTCAGCGGAAGAACTTTATAGAATCGCTCAATCCGG
AGAAGCCAAGGAACTCGAAAAAATTCCAAAGGTAAAAGGTAAAACCTCGGAAAAGATTTTTTTCGAAGTAAAACAAAATC
TTAAAAAGCTGGAACTCTTTTTATCAGGTACTTCAAAAGAACCCTCGATCTCTCTTTCTTCTTTTTCAGAAACACCGGAA
GAAGCCGCTCTTTCCAGAAAAAGAGAAATCGCGATTCTGGGTTTGGTCCAGTTAGGTTTCGAAGAAAAAACCGCCAGCAA
AGAAGTGGATAAAATTCTCAAAAGCTCTTCACCAACCGACCCGGGAGAAATTATCCGTGAAATTTTAAAAAGTTTGTGA

Upstream 100 bases:

>100_bases
TGATATTTTCTTAAAAAACGATTCTCCCGAAATTTTGATCTTCCATGGAAGCATTGGAAATTTATCTTTACTACAATACC
ACGAAATTCCAAGTGGAATC

Downstream 100 bases:

>100_bases
GAGTTCTCCACATCTTTATAAGAAAATCGCCCGTCAATCACCTCAATCCGTATCAGCCAAAAATTTACGGGTATATTCCG
AATCGAAGCTTTCTCATACA

Product: Holliday junction specific DNA binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQKLFGFLTEQDKEFFKVIKGL
QGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPE
EAALSRKREIAILGLVQLGFEEKTASKEVDKILKSSSPTDPGEIIREILKSL

Sequences:

>Translated_212_residues
MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQKLFGFLTEQDKEFFKVIKGL
QGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPE
EAALSRKREIAILGLVQLGFEEKTASKEVDKILKSSSPTDPGEIIREILKSL
>Mature_212_residues
MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQKLFGFLTEQDKEFFKVIKGL
QGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPE
EAALSRKREIAILGLVQLGFEEKTASKEVDKILKSSSPTDPGEIIREILKSL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_LEPBJ (Q04RG9)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801259.1
- ProteinModelPortal:   Q04RG9
- STRING:   Q04RG9
- GeneID:   4411401
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1987
- eggNOG:   COG0632
- HOGENOM:   HBG529249
- OMA:   MRIYHES
- ProtClustDB:   CLSK574640
- BioCyc:   LBOR355277:LBJ_1987-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 23738; Mature: 23738

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQ
CCCCHHHHHHHHHHCCEEEEECCEEEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KLFGFLTEQDKEFFKVIKGLQGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
KTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPEEAALSRKREIAILGLVQLGF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHEEHHHHHCC
EEKTASKEVDKILKSSSPTDPGEIIREILKSL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQ
CCCCHHHHHHHHHHCCEEEEECCEEEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
KLFGFLTEQDKEFFKVIKGLQGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
KTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPEEAALSRKREIAILGLVQLGF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHEEHHHHHCC
EEKTASKEVDKILKSSSPTDPGEIIREILKSL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA