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The map label for this gene is wecA [C]

Identifier: 116327664

GI number: 116327664

Start: 1056585

End: 1057631

Strand: Reverse

Name: wecA [C]

Synonym: LBL_0910

Alternate gene names: 116327664

Gene position: 1057631-1056585 (Counterclockwise)

Preceding gene: 116327684

Following gene: 116327659

Centisome position: 29.26

GC content: 41.36

Gene sequence:

>1047_bases
GTGAAACAGATTTCTTTTTTCTGGAACCCCGGACTTTTATGTGTTCTCGTTTTTTTGGTCACGTTCTTTTTCTCCTGGAT
CTATCTCCATTCCAAACGGTTCGCAATCTCGGATATTTCGAACGAAAGAAGTATGCATGTCGGCACGACGAAAAAATCGG
GAGGTATTTGGATCTTTCTTCCGGTTTTTTGTTTGGCAGCGATTTGGTTCGGAGGATTTGAAATTCCGGATCGGAAAATT
CTTCTTTTTTTTGCGGGTTTGTTGTTCTTTTTCTTGATCGGCCTTTCAGACGATCTACTTTCTCTCGGTTCGGGCATCCG
TCTCGTTTTGGAATTTTTTTTCCTGCTTCTTCTTTTTCTCCTAGAACCGATTCAATTTTCGTTTTTGGGTTTCGACACCG
GAAGCGTTCCGGGGATTTCCACGTCGATTTTGATCGTTTACGTTTTGTTCGTCGTCAACGTTTGTAATTTTATGGACGGC
CTGGATACCTATCTTCCCTCTCATTTTCTCCTTGCGGTTTTGGCATTCCCGTTTTTATTTCAATCCCAACTTCCTTCCGT
TTTTTTTTGGATCTGTGCGGGCGTATTCGGTTTTTTGGGTTTCAATTTACCTAAAGCGAAACTTTTTTTAGGAGACGTCG
GTTCGCTTCCTCTCGGTTATTCCATTGCGGTTCTTCCTTTATTTTTTATCGATGAATATCATTGGGCCCGTTTTGAAATC
ACTTCGGCTTTCTTTTTGCTTCCCGTTTTTTTTGTGGACGGTGTCATCACGATCCTACTTCGGCTTAAGAATCGGGAAAA
TATTCTCAAAGCACATCGTATACATCTCTATCAACTAATCGCCGTTAGTTCAGCTAACAAAGGCTTAGTAGCGTTTCTTT
TTACAGCCGCCAACCTTCCGGCTATGTTTCTTTTTGCAATTCATCGCACCGCGGGTATTCCAGGTAGTATCGTATTTTGG
TTTTGTTTAGCGGGTTATACAGGGTTGTATTTTTTATTGTTTCGTAGGTTCGGGTTTTCTACCAGTATCATTGATACGGA
AAAATAG

Upstream 100 bases:

>100_bases
GAACATAAGGTTAGATTCTTTCTTTCTACTTGATTTGGCAATCAAAATCGTTTCGATTTCTGATTGCAGTGAGACTTCTT
CCTTCTAGGCTGGATCGCTA

Downstream 100 bases:

>100_bases
ATGTCAATGGTTAGGACTTTACATTTAAGGATTATTTTCCTGGGTTTGTTCGAGAATCCGATCCAATTCCTCCACAATTC
CCAAATCTCCTTTTTCAGAA

Product: sugar phosphotransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: Family 4 Glycosyl Transferase; Phospho-N-Acetylmuramoyl-Pentapeptide-Transferase; Glycosyl Transferase Group 4 Family Protein; Glycosyl Transferase Family Protein

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKQISFFWNPGLLCVLVFLVTFFFSWIYLHSKRFAISDISNERSMHVGTTKKSGGIWIFLPVFCLAAIWFGGFEIPDRKI
LLFFAGLLFFFLIGLSDDLLSLGSGIRLVLEFFFLLLLFLLEPIQFSFLGFDTGSVPGISTSILIVYVLFVVNVCNFMDG
LDTYLPSHFLLAVLAFPFLFQSQLPSVFFWICAGVFGFLGFNLPKAKLFLGDVGSLPLGYSIAVLPLFFIDEYHWARFEI
TSAFFLLPVFFVDGVITILLRLKNRENILKAHRIHLYQLIAVSSANKGLVAFLFTAANLPAMFLFAIHRTAGIPGSIVFW
FCLAGYTGLYFLLFRRFGFSTSIIDTEK

Sequences:

>Translated_348_residues
MKQISFFWNPGLLCVLVFLVTFFFSWIYLHSKRFAISDISNERSMHVGTTKKSGGIWIFLPVFCLAAIWFGGFEIPDRKI
LLFFAGLLFFFLIGLSDDLLSLGSGIRLVLEFFFLLLLFLLEPIQFSFLGFDTGSVPGISTSILIVYVLFVVNVCNFMDG
LDTYLPSHFLLAVLAFPFLFQSQLPSVFFWICAGVFGFLGFNLPKAKLFLGDVGSLPLGYSIAVLPLFFIDEYHWARFEI
TSAFFLLPVFFVDGVITILLRLKNRENILKAHRIHLYQLIAVSSANKGLVAFLFTAANLPAMFLFAIHRTAGIPGSIVFW
FCLAGYTGLYFLLFRRFGFSTSIIDTEK
>Mature_348_residues
MKQISFFWNPGLLCVLVFLVTFFFSWIYLHSKRFAISDISNERSMHVGTTKKSGGIWIFLPVFCLAAIWFGGFEIPDRKI
LLFFAGLLFFFLIGLSDDLLSLGSGIRLVLEFFFLLLLFLLEPIQFSFLGFDTGSVPGISTSILIVYVLFVVNVCNFMDG
LDTYLPSHFLLAVLAFPFLFQSQLPSVFFWICAGVFGFLGFNLPKAKLFLGDVGSLPLGYSIAVLPLFFIDEYHWARFEI
TSAFFLLPVFFVDGVITILLRLKNRENILKAHRIHLYQLIAVSSANKGLVAFLFTAANLPAMFLFAIHRTAGIPGSIVFW
FCLAGYTGLYFLLFRRFGFSTSIIDTEK

Specific function: Catalyzes The Synthesis Of Und-Pp-Glcnac (Lipid I), The First Lipid-Linked Intermediate Involved In Eca Synthesis. This Lipid Is Also An Acceptor For The Addition Of Subsequent Sugars To Complete The Biosynthesis Of O-Antigen. [C]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39384; Mature: 39384

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQISFFWNPGLLCVLVFLVTFFFSWIYLHSKRFAISDISNERSMHVGTTKKSGGIWIFL
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCEEEEH
PVFCLAAIWFGGFEIPDRKILLFFAGLLFFFLIGLSDDLLSLGSGIRLVLEFFFLLLLFL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
LEPIQFSFLGFDTGSVPGISTSILIVYVLFVVNVCNFMDGLDTYLPSHFLLAVLAFPFLF
HHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSQLPSVFFWICAGVFGFLGFNLPKAKLFLGDVGSLPLGYSIAVLPLFFIDEYHWARFEI
HHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
TSAFFLLPVFFVDGVITILLRLKNRENILKAHRIHLYQLIAVSSANKGLVAFLFTAANLP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCH
AMFLFAIHRTAGIPGSIVFWFCLAGYTGLYFLLFRRFGFSTSIIDTEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKQISFFWNPGLLCVLVFLVTFFFSWIYLHSKRFAISDISNERSMHVGTTKKSGGIWIFL
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCEEEEH
PVFCLAAIWFGGFEIPDRKILLFFAGLLFFFLIGLSDDLLSLGSGIRLVLEFFFLLLLFL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
LEPIQFSFLGFDTGSVPGISTSILIVYVLFVVNVCNFMDGLDTYLPSHFLLAVLAFPFLF
HHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSQLPSVFFWICAGVFGFLGFNLPKAKLFLGDVGSLPLGYSIAVLPLFFIDEYHWARFEI
HHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
TSAFFLLPVFFVDGVITILLRLKNRENILKAHRIHLYQLIAVSSANKGLVAFLFTAANLP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCH
AMFLFAIHRTAGIPGSIVFWFCLAGYTGLYFLLFRRFGFSTSIIDTEK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA