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The map label for this gene is cph1 [H]

Identifier: 116327623

GI number: 116327623

Start: 993552

End: 994940

Strand: Reverse

Name: cph1 [H]

Synonym: LBL_0856

Alternate gene names: 116327623

Gene position: 994940-993552 (Counterclockwise)

Preceding gene: 116327624

Following gene: 116327622

Centisome position: 27.53

GC content: 39.52

Gene sequence:

>1389_bases
TTGAAAAATACAATTGAAAAGAATATCGCCTACGGATTGATCGGGATCGTCGTATTGAACTTCATTATGATCGGATCCGC
ATATTACACATTAAAACAATCCTTAGAACTCAAAAGATGGGAAGTACATATCCGAGAAGTACTCTTGAGCATAGAAGAGA
CTTTTTCCGCCTTCAACGAAGCCCATGCCGTTTTAAGAGCTTATCTTTTGTATCTGGACCAAGAACAACTAAACGCTTAT
TTCAAAAGTAAAAGCCTAGTTTTAGAACGAATTGAAAAACTTCGAAAGAGCGTAATCGATAACCCTTCCCAGCAGCAGAG
ACTTTCTCTCGTAGAAACCCACTTAAATGAAAAGTTTTCCTACATGGACAAATTGGTTTTAATGAGAAAACACGCATCCA
TGCAATATTATTTGCCGCTATTTCGTTCCGCACAGGGAAAAGACCTATCGGAAAAAATCAAATCCCTCATTCAGGACATA
AAAACGGAAGAACTTCGACTCCTAAACATGCGAACAAACAATCCGAAAATGCATCTGACGATATCGGTCACTCTGCTTTT
CTCCGGAATCACATTGAATCTTCTTTTCATTTTCCTTCAAAACTGGTCCATCTATAAAGAAAGTCAACGTCGTCAAAAAG
CGGAAAGTGTATTGGAAATATCCAATCAAAATCTCAAAACATATTCGGAACGACTGGAAAGATCGAACAAAGACTTAGAA
GCATTCTCTTATTCCGTTTCACACGACCTTCGTTCTCCAATCCGAGGTATATTAGGATTTTCTAAAATACTACTGGAGGA
TTACGGAACGGAACTCGGAGAGGAAAGCCGTAGAATCGTCAACATAATCATTCAAAGCTCCGAGAATATGGGGGAACTCA
TAGACGATCTTCTGGAATATTCAAGATTGGGAAGAAGAGAGCCCATATTCTCCGTCGTGAATATGCAATCCATAGTGGAA
AAAATCCTCGAGGAAGTAGCGAACTATTATCCGGATATGAAAATGGAAACCGTCGTGGGAAATCTCCCTCCGACAAAAGG
GGACCCCAGTCTACTGAAACAACTTTTATTCAATTTGATTTCCAATTCCTTCAAATATTCCAAAAAGAAAGAAAATCCGA
AAATCGAAATCGGATCCTACCAAAACGATGGAGAGACCGTATTCTTCGTAAAAGACAACGGGGCAGGATTCGATATGAAA
TACCAACATAAACTATTCAATATCTTTCAAAGGCTACATCATGCGGATCAGTTTGAAGGAACCGGAGTCGGACTTGCCAT
CGTAAAAAGGGTGATCGAAAGACACAACGGCAAGGTTTGGGGAAATAGCAAATTGAACGAAGGCGCTTGTTTTTATTTTA
CCCTAGGAGTTGGCGACAATCATGTATGA

Upstream 100 bases:

>100_bases
AGGAAAAGAGTGATCGCAATTTTTATTTTCGGAATCGCTAGGTTTAGACTTCGGGTGAATGAGCGATTCCTAATACTGAA
TCGTGCTCGAGGTGTTTCCT

Downstream 100 bases:

>100_bases
TCTTCAGGACCAATCAATCTCGATCTTATACGCGGAAGACAATCCGCAAGACTCGGAACTTACTCTCAGAAGCTTAAAAA
GACACAATCTCACGAATCAA

Product: sensor histidine kinase of a two component response regulator

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKNTIEKNIAYGLIGIVVLNFIMIGSAYYTLKQSLELKRWEVHIREVLLSIEETFSAFNEAHAVLRAYLLYLDQEQLNAY
FKSKSLVLERIEKLRKSVIDNPSQQQRLSLVETHLNEKFSYMDKLVLMRKHASMQYYLPLFRSAQGKDLSEKIKSLIQDI
KTEELRLLNMRTNNPKMHLTISVTLLFSGITLNLLFIFLQNWSIYKESQRRQKAESVLEISNQNLKTYSERLERSNKDLE
AFSYSVSHDLRSPIRGILGFSKILLEDYGTELGEESRRIVNIIIQSSENMGELIDDLLEYSRLGRREPIFSVVNMQSIVE
KILEEVANYYPDMKMETVVGNLPPTKGDPSLLKQLLFNLISNSFKYSKKKENPKIEIGSYQNDGETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHADQFEGTGVGLAIVKRVIERHNGKVWGNSKLNEGACFYFTLGVGDNHV

Sequences:

>Translated_462_residues
MKNTIEKNIAYGLIGIVVLNFIMIGSAYYTLKQSLELKRWEVHIREVLLSIEETFSAFNEAHAVLRAYLLYLDQEQLNAY
FKSKSLVLERIEKLRKSVIDNPSQQQRLSLVETHLNEKFSYMDKLVLMRKHASMQYYLPLFRSAQGKDLSEKIKSLIQDI
KTEELRLLNMRTNNPKMHLTISVTLLFSGITLNLLFIFLQNWSIYKESQRRQKAESVLEISNQNLKTYSERLERSNKDLE
AFSYSVSHDLRSPIRGILGFSKILLEDYGTELGEESRRIVNIIIQSSENMGELIDDLLEYSRLGRREPIFSVVNMQSIVE
KILEEVANYYPDMKMETVVGNLPPTKGDPSLLKQLLFNLISNSFKYSKKKENPKIEIGSYQNDGETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHADQFEGTGVGLAIVKRVIERHNGKVWGNSKLNEGACFYFTLGVGDNHV
>Mature_462_residues
MKNTIEKNIAYGLIGIVVLNFIMIGSAYYTLKQSLELKRWEVHIREVLLSIEETFSAFNEAHAVLRAYLLYLDQEQLNAY
FKSKSLVLERIEKLRKSVIDNPSQQQRLSLVETHLNEKFSYMDKLVLMRKHASMQYYLPLFRSAQGKDLSEKIKSLIQDI
KTEELRLLNMRTNNPKMHLTISVTLLFSGITLNLLFIFLQNWSIYKESQRRQKAESVLEISNQNLKTYSERLERSNKDLE
AFSYSVSHDLRSPIRGILGFSKILLEDYGTELGEESRRIVNIIIQSSENMGELIDDLLEYSRLGRREPIFSVVNMQSIVE
KILEEVANYYPDMKMETVVGNLPPTKGDPSLLKQLLFNLISNSFKYSKKKENPKIEIGSYQNDGETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHADQFEGTGVGLAIVKRVIERHNGKVWGNSKLNEGACFYFTLGVGDNHV

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=27.6859504132231, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=26.5060240963855, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=26.1802575107296, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=27.3469387755102, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=210, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=277, Percent_Identity=25.2707581227437, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=25.8333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=193, Percent_Identity=25.9067357512953, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=28.2407407407407, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=22.3744292237443, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=24, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=244, Percent_Identity=25.4098360655738, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53467; Mature: 53467

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTIEKNIAYGLIGIVVLNFIMIGSAYYTLKQSLELKRWEVHIREVLLSIEETFSAFNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHAVLRAYLLYLDQEQLNAYFKSKSLVLERIEKLRKSVIDNPSQQQRLSLVETHLNEKFS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YMDKLVLMRKHASMQYYLPLFRSAQGKDLSEKIKSLIQDIKTEELRLLNMRTNNPKMHLT
HHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEEEEECCCCEEEEE
ISVTLLFSGITLNLLFIFLQNWSIYKESQRRQKAESVLEISNQNLKTYSERLERSNKDLE
EEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
AFSYSVSHDLRSPIRGILGFSKILLEDYGTELGEESRRIVNIIIQSSENMGELIDDLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
SRLGRREPIFSVVNMQSIVEKILEEVANYYPDMKMETVVGNLPPTKGDPSLLKQLLFNLI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
SNSFKYSKKKENPKIEIGSYQNDGETVFFVKDNGAGFDMKYQHKLFNIFQRLHHADQFEG
HHHHHCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
TGVGLAIVKRVIERHNGKVWGNSKLNEGACFYFTLGVGDNHV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKNTIEKNIAYGLIGIVVLNFIMIGSAYYTLKQSLELKRWEVHIREVLLSIEETFSAFNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHAVLRAYLLYLDQEQLNAYFKSKSLVLERIEKLRKSVIDNPSQQQRLSLVETHLNEKFS
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
YMDKLVLMRKHASMQYYLPLFRSAQGKDLSEKIKSLIQDIKTEELRLLNMRTNNPKMHLT
HHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEEEEECCCCEEEEE
ISVTLLFSGITLNLLFIFLQNWSIYKESQRRQKAESVLEISNQNLKTYSERLERSNKDLE
EEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
AFSYSVSHDLRSPIRGILGFSKILLEDYGTELGEESRRIVNIIIQSSENMGELIDDLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
SRLGRREPIFSVVNMQSIVEKILEEVANYYPDMKMETVVGNLPPTKGDPSLLKQLLFNLI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
SNSFKYSKKKENPKIEIGSYQNDGETVFFVKDNGAGFDMKYQHKLFNIFQRLHHADQFEG
HHHHHCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
TGVGLAIVKRVIERHNGKVWGNSKLNEGACFYFTLGVGDNHV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]