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The map label for this gene is sucC

Identifier: 116327602

GI number: 116327602

Start: 965358

End: 966530

Strand: Reverse

Name: sucC

Synonym: LBL_0834

Alternate gene names: 116327602

Gene position: 966530-965358 (Counterclockwise)

Preceding gene: 116327606

Following gene: 116327601

Centisome position: 26.74

GC content: 49.02

Gene sequence:

>1173_bases
ATGAAAATTCACGAGTATCAGGCAAAAGAAATCCTGAGAAGGCACAAAGCCAACGTTCCTTTTGGAATCGTAATCGACAA
AAAAGAAAACGCATCCAAAGCCCATGACGAAGTTACCTCCAAAACCGGCGGTTCCGTCGTAGTCGTAAAAGCGCAGATCC
ATGCAGGCGGACGCGGAAAAGGCGGCGGTGTTAAAGTAACCAAAACCAAAGAAGACGCAACCGCAGCCGTAGACAAAATT
CTCGGAATGCAGCTCATCACTCCCCAAACCGGACCCGAAGGAAAAAAAGTCCTGAAAGTATATCTGGAGCAGGGAATCGA
TATCGCAAAGGAATATTATCTCAGTATCCTTCTCGATCGTTCCATCCGTAAGACCATCCTTATGGCTTCCACCGAAGGCG
GAATGGAAATCGAAGAAGTTGCCGAAACTCATCCTGAAAAGATTTTAAAAATCGCCGTGGATCCCGGAATCGGACTTCAA
GTGAACCAAGCAAGACAACTCGCTTTCGAACTCGGACTTCCCGCAGAATCGCACAAGTCTTTTCAAAGCCTCGTTATGGC
GATCTATGACGCGTATATCAAAGAAGACGCTTCTCTTTTAGAAATCAATCCTCTCATTCTCACCAAACAGAATGAAATCA
TCGCGGGAGATTGCAAGATCGACCTCGACGAAAACGCTCTCTACCGTCACGCGGACAACGCGGCATTCAGAGACATCACC
GAAGAGGATCCTCTCGAAGTTCAGGCTTCCGAGTTCAACCTCAACTACGTCAAGTTAGACGGCAACATCGGTTGTATGGT
CAACGGAGCCGGACTCGCGATGGCGACCATGGACATCGTAAAACTCGCGGGCGCGGAACCTGCGAACTTTTTGGACGTAG
GAGGCGGGGCGAACAAAACCACTGTAACCAACGGATTCAAAATCATCCTCGGTGATCCGAACGTAAAAGGAATCTTCGTA
AACATCTTCGGCGGGATCGTTCGTTGCGACATGGTCGCGGAAGGAATCATCGAAGCGGCTAAAGCCGTGGATTTGAAAGT
TCCTCTCGTGGTTCGTCTCCAAGGAACCAACTCGGAACTCGGAAGAGAAGTCCTCAACAAAAGCGGACTGAAAATTACCG
GAGTCGACGACCTCCGCGAAGCGGCAAGCACCATTGCCAAACTGATCAAGTAA

Upstream 100 bases:

>100_bases
TACTGACACCAGAGTTCCTACCGAAAACAGTATAAATTTCGAGTAAATCATACCTCCTACTAAAAAGAAGCACTGAACTA
AGTTCAATGAAGGTTAATTC

Downstream 100 bases:

>100_bases
GAGAGAACACACATGGCAGTATTAGTAGACGAAAATACAAAAGTCGTAGTCCAAGGGATCACCGGTAAGGAAGGTTCTTT
CCACGCGACACAAATGCTCG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGKGGGVKVTKTKEDATAAVDKI
LGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDRSIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQ
VNQARQLAFELGLPAESHKSFQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDIT
EEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKTTVTNGFKIILGDPNVKGIFV
NIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSELGREVLNKSGLKITGVDDLREAASTIAKLIK

Sequences:

>Translated_390_residues
MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGKGGGVKVTKTKEDATAAVDKI
LGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDRSIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQ
VNQARQLAFELGLPAESHKSFQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDIT
EEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKTTVTNGFKIILGDPNVKGIFV
NIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSELGREVLNKSGLKITGVDDLREAASTIAKLIK
>Mature_390_residues
MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGKGGGVKVTKTKEDATAAVDKI
LGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDRSIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQ
VNQARQLAFELGLPAESHKSFQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDIT
EEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKTTVTNGFKIILGDPNVKGIFV
NIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSELGREVLNKSGLKITGVDDLREAASTIAKLIK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=398, Percent_Identity=43.21608040201, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI157779135, Length=389, Percent_Identity=42.4164524421594, Blast_Score=304, Evalue=9e-83,
Organism=Homo sapiens, GI294862256, Length=368, Percent_Identity=42.3913043478261, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=51.6883116883117, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=43.3673469387755, Blast_Score=327, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=397, Percent_Identity=44.080604534005, Blast_Score=326, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=400, Percent_Identity=43.5, Blast_Score=333, Evalue=3e-92,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=44.1025641025641, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=44.1025641025641, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=45.8015267175573, Blast_Score=314, Evalue=8e-86,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=43.9897698209719, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=43.9897698209719, Blast_Score=313, Evalue=1e-85,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_LEPBJ (Q04QS3)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801505.1
- ProteinModelPortal:   Q04QS3
- SMR:   Q04QS3
- STRING:   Q04QS3
- GeneID:   4410996
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2273
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   MADGAEK
- PhylomeDB:   Q04QS3
- ProtClustDB:   PRK00696
- BioCyc:   LBOR355277:LBJ_2273-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41982; Mature: 41982

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGK
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCC
GGGVKVTKTKEDATAAVDKILGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDR
CCCEEEEECCCHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
SIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQVNQARQLAFELGLPAESHKS
HHHHEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCEEECHHHHHHHHCCCCCHHHHH
FQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDIT
HHHHHHHHHHHHHHCCCCEEEECEEEEECCCCEEEECEEEECCCCHHHCCCCCCHHCCCC
EEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKT
CCCCCEEEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCC
TVTNGFKIILGDPNVKGIFVNIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSEL
EEECCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCEECCEEEEEECCCHHH
GREVLNKSGLKITGVDDLREAASTIAKLIK
HHHHHHCCCCEEECHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGK
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEEEEECCCCCC
GGGVKVTKTKEDATAAVDKILGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDR
CCCEEEEECCCHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
SIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQVNQARQLAFELGLPAESHKS
HHHHEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCEEECHHHHHHHHCCCCCHHHHH
FQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDIT
HHHHHHHHHHHHHHCCCCEEEECEEEEECCCCEEEECEEEECCCCHHHCCCCCCHHCCCC
EEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKT
CCCCCEEEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCC
TVTNGFKIILGDPNVKGIFVNIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSEL
EEECCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCEECCEEEEEECCCHHH
GREVLNKSGLKITGVDDLREAASTIAKLIK
HHHHHHCCCCEEECHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA