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The map label for this gene is crp [C]

Identifier: 116327430

GI number: 116327430

Start: 716131

End: 716763

Strand: Reverse

Name: crp [C]

Synonym: LBL_0644

Alternate gene names: 116327430

Gene position: 716763-716131 (Counterclockwise)

Preceding gene: 116327436

Following gene: 116327429

Centisome position: 19.83

GC content: 39.34

Gene sequence:

>633_bases
ATGGAAATAACAGAATCTATGACCCATAAGCTGGGTGTCGAGTTCAAGGAATCCGATATTATCTTTGAGGAAAATCAAGA
AGCGGAAGTGATGTACTTGATCGCCAAAGGAAAAGTAAGGATTCATAAAAAAGTAAAAGAAGCCTATAAACTCCTCGTAG
AATTAAAAGAGGGGGATATGTTCGGCGAAATGGCACTAATCGATAAGACGCCTCGAAGTGCGAGGGCCGTCGCAAGGACG
GACGTTTTGCTCATAGCAATCAATAAGGATGCATTTTTCAATCTGATACGAACAAATCCCGGATTTTCCATGAAGATCGT
TAAAATTCTCACCTCAAGACTGAGAGAAACGAATAAGACAATCGCTACTCTTTTGAAAGCGGATAAAAAGAATTTAGTGA
CCTCCGCTTTGATTAACTTTTCGCAAGCAAACGGACAACAGGATGGAAGTAATTATCGAATTCCTCTGAATCATTTCATC
AAATGGGCAATCCTTAGAGTCGGATTGGAACACCAAGACTTAGTAAGCTCCATCAGACTATTAGTAAAAGATAAAATGGT
GGAACAAATAAAAGAAGATCCTTCGACCCTGATTATTCGAGACTCTCTTTTCAAATATACGGTGGACACTTGA

Upstream 100 bases:

>100_bases
GATTCCAATTTCCAATCTGGTGTAGACTTTCTAAGTGATCTTCAATTCCTAAAAACAACCAAAATCTTTGGAAAATTATA
ATTCAGGCCCGTTAAGAATT

Downstream 100 bases:

>100_bases
ACCCTCAACCGATCTTATCAAAAACCAGAAAAAGACTTTTTTATTTAGACAATCTCCGTTCTTTTGCTCTTTTAATCGGT
CTCGTATTTCATGTCGCGAT

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Transcriptional Regulatory Protein; Crp Family Transcriptional Regulator; Histidine Kinase; CRP Family Transcriptional Regulator; Catabolite Gene Activator; Crp-Family Transcriptional Regulator; CAAX Amino Terminal Protease Family; Transcription Regulator; CAMP-Dependent Protein Kinase; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MEITESMTHKLGVEFKESDIIFEENQEAEVMYLIAKGKVRIHKKVKEAYKLLVELKEGDMFGEMALIDKTPRSARAVART
DVLLIAINKDAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQANGQQDGSNYRIPLNHFI
KWAILRVGLEHQDLVSSIRLLVKDKMVEQIKEDPSTLIIRDSLFKYTVDT

Sequences:

>Translated_210_residues
MEITESMTHKLGVEFKESDIIFEENQEAEVMYLIAKGKVRIHKKVKEAYKLLVELKEGDMFGEMALIDKTPRSARAVART
DVLLIAINKDAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQANGQQDGSNYRIPLNHFI
KWAILRVGLEHQDLVSSIRLLVKDKMVEQIKEDPSTLIIRDSLFKYTVDT
>Mature_210_residues
MEITESMTHKLGVEFKESDIIFEENQEAEVMYLIAKGKVRIHKKVKEAYKLLVELKEGDMFGEMALIDKTPRSARAVART
DVLLIAINKDAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQANGQQDGSNYRIPLNHFI
KWAILRVGLEHQDLVSSIRLLVKDKMVEQIKEDPSTLIIRDSLFKYTVDT

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23996; Mature: 23996

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITESMTHKLGVEFKESDIIFEENQEAEVMYLIAKGKVRIHKKVKEAYKLLVELKEGDM
CCCHHHHHHHHCCEECCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
FGEMALIDKTPRSARAVARTDVLLIAINKDAFFNLIRTNPGFSMKIVKILTSRLRETNKT
CCCEEEECCCCCHHHHHHHCCEEEEEECCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHH
IATLLKADKKNLVTSALINFSQANGQQDGSNYRIPLNHFIKWAILRVGLEHQDLVSSIRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHH
LVKDKMVEQIKEDPSTLIIRDSLFKYTVDT
HHHHHHHHHHHCCCCEEEEECCCEEEECCC
>Mature Secondary Structure
MEITESMTHKLGVEFKESDIIFEENQEAEVMYLIAKGKVRIHKKVKEAYKLLVELKEGDM
CCCHHHHHHHHCCEECCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
FGEMALIDKTPRSARAVARTDVLLIAINKDAFFNLIRTNPGFSMKIVKILTSRLRETNKT
CCCEEEECCCCCHHHHHHHCCEEEEEECCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHH
IATLLKADKKNLVTSALINFSQANGQQDGSNYRIPLNHFIKWAILRVGLEHQDLVSSIRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHH
LVKDKMVEQIKEDPSTLIIRDSLFKYTVDT
HHHHHHHHHHHCCCCEEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA