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The map label for this gene is btuE-2 [H]

Identifier: 116327308

GI number: 116327308

Start: 549996

End: 550544

Strand: Reverse

Name: btuE-2 [H]

Synonym: LBL_0500

Alternate gene names: 116327308

Gene position: 550544-549996 (Counterclockwise)

Preceding gene: 116327310

Following gene: 116327307

Centisome position: 15.23

GC content: 37.89

Gene sequence:

>549_bases
ATGTATCCAAAAATTTCCGTTTTGTTTTTCATCTTAGGAATTCTCTTTCCGTTAGCCGGAACTTTTGCAAAGGAAAGTTT
CTACGATTTTAAGGTAAAGGACATCAAAGGTAACGAGATATCACTTTCCAAATACAAGGGGAAAGTAGTAATGGTGGTTA
ACGTAGCTTCTAAATGCGGTTATACTTATCAATACGATAATCTTGAAAAAGTCTATAAAAAATACAAGAATCAGGGGTTC
GTCGTAGTAGGTTTTCCGGCTAATAATTTCGGAAGCCAAGAACCTGGAACCAATCAGGAAATTGAAACTTTTTGCAGAAT
CCAAAAAGGCGCAAGTTTTGATATGATGTCGAAAATTTCCGTCAAAGGAAAAGACCAACATCCCCTATATTCTTATCTGA
TCGAAAATTCTCCGAATCCCGGAGAAATAGAATGGAACTTTGAAAAGTTTCTCATTTCAAAGGAAGGAAAAGTCGAAGCG
AGATATCGCTCCGCGGTAGAGCCGGATGCTTCGGTCGTAGCCCAGAAAATCGAATCTCTTTTAAAGTAG

Upstream 100 bases:

>100_bases
CTCTTCCTTGATAATTACGAAAAGGTAATTTCCGATTTTTGAAAAACGATTGAAGCAAACGTGGATTATGATTTTAATTC
ATAGAAGAAGGTCAAAATCT

Downstream 100 bases:

>100_bases
GTTTTTAATTTTGAAAGATCCCCGTTCAAGAACTTGCTCTTTTACGATTTTTCTTTTTAAAATACGGTTTCTTGCGCTTC
TGCTGATTTTTTGCTCGGAA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MYPKISVLFFILGILFPLAGTFAKESFYDFKVKDIKGNEISLSKYKGKVVMVVNVASKCGYTYQYDNLEKVYKKYKNQGF
VVVGFPANNFGSQEPGTNQEIETFCRIQKGASFDMMSKISVKGKDQHPLYSYLIENSPNPGEIEWNFEKFLISKEGKVEA
RYRSAVEPDASVVAQKIESLLK

Sequences:

>Translated_182_residues
MYPKISVLFFILGILFPLAGTFAKESFYDFKVKDIKGNEISLSKYKGKVVMVVNVASKCGYTYQYDNLEKVYKKYKNQGF
VVVGFPANNFGSQEPGTNQEIETFCRIQKGASFDMMSKISVKGKDQHPLYSYLIENSPNPGEIEWNFEKFLISKEGKVEA
RYRSAVEPDASVVAQKIESLLK
>Mature_182_residues
MYPKISVLFFILGILFPLAGTFAKESFYDFKVKDIKGNEISLSKYKGKVVMVVNVASKCGYTYQYDNLEKVYKKYKNQGF
VVVGFPANNFGSQEPGTNQEIETFCRIQKGASFDMMSKISVKGKDQHPLYSYLIENSPNPGEIEWNFEKFLISKEGKVEA
RYRSAVEPDASVVAQKIESLLK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=162, Percent_Identity=43.2098765432099, Blast_Score=128, Evalue=3e-30,
Organism=Homo sapiens, GI75709200, Length=164, Percent_Identity=40.8536585365854, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=37.9746835443038, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI90903240, Length=149, Percent_Identity=42.2818791946309, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI90903238, Length=146, Percent_Identity=39.7260273972603, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI4557629, Length=162, Percent_Identity=35.8024691358025, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI41406084, Length=190, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.8342541436464, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI6006001, Length=161, Percent_Identity=33.5403726708075, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI33186887, Length=178, Percent_Identity=30.3370786516854, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788003, Length=180, Percent_Identity=40, Blast_Score=146, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17550320, Length=183, Percent_Identity=34.9726775956284, Blast_Score=122, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI193209493, Length=183, Percent_Identity=34.4262295081967, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71993584, Length=171, Percent_Identity=38.5964912280702, Blast_Score=112, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17506887, Length=147, Percent_Identity=39.4557823129252, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193210707, Length=167, Percent_Identity=36.5269461077844, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535473, Length=146, Percent_Identity=36.3013698630137, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71999642, Length=79, Percent_Identity=43.0379746835443, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71993573, Length=120, Percent_Identity=36.6666666666667, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193210709, Length=91, Percent_Identity=42.8571428571429, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=161, Percent_Identity=48.4472049689441, Blast_Score=154, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=47.8260869565217, Blast_Score=151, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6322826, Length=147, Percent_Identity=39.4557823129252, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24656767, Length=181, Percent_Identity=40.8839779005525, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=43.75, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=43.75, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=36.7088607594937, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20663; Mature: 20663

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPKISVLFFILGILFPLAGTFAKESFYDFKVKDIKGNEISLSKYKGKVVMVVNVASKCG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCEEEEEEEEHHHCC
YTYQYDNLEKVYKKYKNQGFVVVGFPANNFGSQEPGTNQEIETFCRIQKGASFDMMSKIS
CEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHEE
VKGKDQHPLYSYLIENSPNPGEIEWNFEKFLISKEGKVEARYRSAVEPDASVVAQKIESL
CCCCCCCCHHHHHCCCCCCCCEEEECHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHHH
LK
HC
>Mature Secondary Structure
MYPKISVLFFILGILFPLAGTFAKESFYDFKVKDIKGNEISLSKYKGKVVMVVNVASKCG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCEEEEEEEEHHHCC
YTYQYDNLEKVYKKYKNQGFVVVGFPANNFGSQEPGTNQEIETFCRIQKGASFDMMSKIS
CEEECCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHEE
VKGKDQHPLYSYLIENSPNPGEIEWNFEKFLISKEGKVEARYRSAVEPDASVVAQKIESL
CCCCCCCCHHHHHCCCCCCCCEEEECHHHEEECCCCCCHHHHHHCCCCCHHHHHHHHHHH
LK
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]