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The map label for this gene is queC

Identifier: 116327179

GI number: 116327179

Start: 417749

End: 418477

Strand: Reverse

Name: queC

Synonym: LBL_0358

Alternate gene names: 116327179

Gene position: 418477-417749 (Counterclockwise)

Preceding gene: 116327180

Following gene: 116327178

Centisome position: 11.58

GC content: 40.05

Gene sequence:

>729_bases
TTGAATTCGAGAAAAGATAAGAATTCGAAAGGAAAGAATTCCGATACGAAACGGAAGAAATCCTCGCAAGAAAACGACAA
GGCTGTTGTCCTTTTATCGGGCGGACTCGATTCCACAACTTGTTTGTATCAGGCGTTGGCAGACGGAAAAAAAATCCAAG
CTCTTTCCTTCGACTACGGACAAAAACATAAAATTGAATTGTCTTATGCGAAAAAAATAACCCGCCAATTAGGAATTTCT
CATACAATTCAAAAGTTAAAACCGGAATTATTTTTAGGTTCGTCACTGACTCAGAAATCGCTCAGAGTTCCTAAAAATTC
TTTAGGAAAAGAAGAAATTCCGAACACTTATGTTCCCGGGCGAAATATTCTATTTCTTTCCTTTGCGGTTTGTCTTGCGG
AAGGTACCGGTTCAAATTCCATCTATATCGGAGTGAATGCAATGGACTATTCCGGTTATCCGGATTGCAGACCGGAGTTT
ATCAAAACATACGAAACGGCGATTCAACTCGGAACCAAAAAAGGAAATCAAGGTTCCCCGATTAAAATCGTGACTCCTCT
CCAAAATCTTTCCAAAAAAGAAATCGTTCTTCTGGGAAATCGACTACAAGTACCCTTTCATCTTACATTCTCCTGTTATG
ACCCGAAGAACAGGAAAGCATGTGGAAAATGCGACGCCTGTCTCCTGAGAAAAAAAGGTTTTCAGGAGACCGGAGTTTCT
GAAAAGTGA

Upstream 100 bases:

>100_bases
CTTTGCTTTATAAAATCACTCTGAATGAAACTTGCACAAGTGCTTGTATTTATGAAGGTCCGAAAAATTCTTCTCAAGGA
TAACGAAGGTTAAGTAAAAT

Downstream 100 bases:

>100_bases
TTTCATCGGTTGGCATTTGTTAACCCAACCTTCCTCAGCTCTCCAAAGGAAGGAATCTCTTTTTAGGAAAAGTTAAAATG
GAACAGTTCGTAGGTTACCT

Product: PP-loop superfamily ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYGQKHKIELSYAKKITRQLGIS
HTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPGRNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEF
IKTYETAIQLGTKKGNQGSPIKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVS
EK

Sequences:

>Translated_242_residues
MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYGQKHKIELSYAKKITRQLGIS
HTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPGRNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEF
IKTYETAIQLGTKKGNQGSPIKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVS
EK
>Mature_242_residues
MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYGQKHKIELSYAKKITRQLGIS
HTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPGRNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEF
IKTYETAIQLGTKKGNQGSPIKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVS
EK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=40.2777777777778, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_LEPBJ (Q04PP1)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801887.1
- ProteinModelPortal:   Q04PP1
- SMR:   Q04PP1
- STRING:   Q04PP1
- GeneID:   4411117
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2716
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q04PP1
- ProtClustDB:   CLSK573455
- BioCyc:   LBOR355277:LBJ_2716-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26774; Mature: 26774

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYG
CCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
QKHKIELSYAKKITRQLGISHTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPG
CCEEEEHHHHHHHHHHHCHHHHHHHHCCCEEECCCHHHHHHCCCHHHCCHHHCCCCCCCC
RNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEFIKTYETAIQLGTKKGNQGSP
CCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
IKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVS
EEEECCCCCCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
EK
CC
>Mature Secondary Structure
MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYG
CCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCC
QKHKIELSYAKKITRQLGISHTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPG
CCEEEEHHHHHHHHHHHCHHHHHHHHCCCEEECCCHHHHHHCCCHHHCCHHHCCCCCCCC
RNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEFIKTYETAIQLGTKKGNQGSP
CCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
IKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVS
EEEECCCCCCCCCEEEEECCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA