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The map label for this gene is pntAB [H]

Identifier: 116327178

GI number: 116327178

Start: 417387

End: 417671

Strand: Reverse

Name: pntAB [H]

Synonym: LBL_0357

Alternate gene names: 116327178

Gene position: 417671-417387 (Counterclockwise)

Preceding gene: 116327179

Following gene: 116327177

Centisome position: 11.56

GC content: 43.86

Gene sequence:

>285_bases
ATGGAACAGTTCGTAGGTTACCTGACGATCTTCTTACTGGCCGTATTTGTCGGCTTCGAAGTGATCACAAGAATTCCTCC
TCTTTTACATACTCCTCTTATGTCAGGTTCCAACGCTATTTCCGGAATCACGATCATTGGAGCGATTCTCTCTCTTCATT
CCGTGAATGGACCGCTAATCAATATCATCGGATTTATCGCGATGGTCGCCGCAACGATCAACGTTGTAGGCGGGTTCTTA
GTGACCCATAGAATGTTGGGAATGTTCAAGAAGAAAGAAAAATAA

Upstream 100 bases:

>100_bases
AGACCGGAGTTTCTGAAAAGTGATTTCATCGGTTGGCATTTGTTAACCCAACCTTCCTCAGCTCTCCAAAGGAAGGAATC
TCTTTTTAGGAAAAGTTAAA

Downstream 100 bases:

>100_bases
GAATATGGAAAAGTCGATCATCAATTTAGTTTATCTTCTATCCTCGATCCTTTTTATCGTAGGATTAAAACTTCTTTCTC
ACCCAAAGACCGCAGTCAAA

Product: NAD(P)(+) transhydrogenase-related

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MEQFVGYLTIFLLAVFVGFEVITRIPPLLHTPLMSGSNAISGITIIGAILSLHSVNGPLINIIGFIAMVAATINVVGGFL
VTHRMLGMFKKKEK

Sequences:

>Translated_94_residues
MEQFVGYLTIFLLAVFVGFEVITRIPPLLHTPLMSGSNAISGITIIGAILSLHSVNGPLINIIGFIAMVAATINVVGGFL
VTHRMLGMFKKKEK
>Mature_94_residues
MEQFVGYLTIFLLAVFVGFEVITRIPPLLHTPLMSGSNAISGITIIGAILSLHSVNGPLINIIGFIAMVAATINVVGGFL
VTHRMLGMFKKKEK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=90, Percent_Identity=42.2222222222222, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI122939153, Length=90, Percent_Identity=42.2222222222222, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787887, Length=90, Percent_Identity=47.7777777777778, Blast_Score=87, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17550456, Length=94, Percent_Identity=40.4255319148936, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10112; Mature: 10112

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFVGYLTIFLLAVFVGFEVITRIPPLLHTPLMSGSNAISGITIIGAILSLHSVNGPLI
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHH
NIIGFIAMVAATINVVGGFLVTHRMLGMFKKKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQFVGYLTIFLLAVFVGFEVITRIPPLLHTPLMSGSNAISGITIIGAILSLHSVNGPLI
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHH
NIIGFIAMVAATINVVGGFLVTHRMLGMFKKKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]