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The map label for this gene is serC [H]

Identifier: 116327142

GI number: 116327142

Start: 375000

End: 376127

Strand: Reverse

Name: serC [H]

Synonym: LBL_0318

Alternate gene names: 116327142

Gene position: 376127-375000 (Counterclockwise)

Preceding gene: 116327144

Following gene: 116327141

Centisome position: 10.41

GC content: 42.11

Gene sequence:

>1128_bases
TTGATCCCCAACCTCCCTTTTGTAACCTTATCCCTTATGTATTTGTTCCAAGAAAGAATCTATAATTTCGGCGCGGGTCC
GGCGATGCTTCCCAACGAAGTGATGGAGATCGCAGCGGCCGAATTCTTAAACTATAAAGGCTCCGGAATGTCCGTTATGG
AAGTCAGTCACAGAGAACCTCTTTTTGAAGACGTGATCAAAAAAGCGGAAATCCTTTTGCGCGAGCTTCTCGATCTTGAA
GACGATTACTCCGTCGCATTTTTTTCGGGAGGAGCCACTTTACATTTTTCCGCTTTACCTCTCAATCTTCTGAAAGAAGG
AGAAAGTTTCGACATAGCTCACACCGGAATCTGGACAAAAAAAGCTTGGGAAGAAGGTCTTAAATTCAACGAAGTCAACA
TTATCCACGACGCGACGGAAAATCATTTTACAGATACTCCGGTATTGACCGACGCAAACCTTTCCGGAAAAGGAAAATAT
CTTCATATTACTTCTAACAATACAATCTACGGATCTCAATATCCCGAACTCCCTAAAATCAAACGGGTCCCTCTCGTTGC
CGATATGACGAGCGAACTATTATCCCGTAAAATCAACGTGAAAGATTTCGGAATCATTTTTGCCGGCGCTCAAAAAAACA
TCGGGCCTTCCGGACTCAGTCTCGCAATTATCCGAAACGATCTACTCGGAATTTCAGGAAGAAAAATTCCGGTTCTTTTA
GATTATTCCGTGATGGTAAAGAACCAATCTCTTTACAATACTCCTTCTACGTATTCCATTTATATCGCTAAACTCGTTTT
TGAGTGGCTCTTAAAGTTAGGCGGAATCGAAGCTATCGAAAAGGTTAACGAGCAAAAAGCAAACTTAATCTACGACTTTA
TCGATTCTTCGTCCTTATATACATGCCCGGTTCAAAAAAGATCCCGCTCCAAGATGAACGTGGTATTTTTACTCAGAGAC
AAGAATTTGGATTCCAAGTTTTTGGACGAAGCGGAAAAGAACGGCTTGCACGGTTTAGGCGGACATAGATTGGTGGGAGG
ATTTAGAGCTTCGATTTATAATTCCATGCCTCTGGCGGGCGTTCAAAAACTCGTCTCTTTTATGAAGGAATTCGAATCCA
AAACTTGA

Upstream 100 bases:

>100_bases
CAAAGTGAAAGACTCGTTTGATCGGAGAATATGTTATTCTCAGGCATTCTATCGAGACAAGGATTTTTCCCGATCCGGAG
TTTTCTTTGTCGGAAGAAAG

Downstream 100 bases:

>100_bases
TGAAATTTTCACCTTTTAGAAATATCTTTTTGACCTCGATATCGATCGGAATTTATTCTGGAAGTCTTATTGCTTCCGGA
CTGAATTTCAATACACAATC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIPNLPFVTLSLMYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREPLFEDVIKKAEILLRELLDLE
DDYSVAFFSGGATLHFSALPLNLLKEGESFDIAHTGIWTKKAWEEGLKFNEVNIIHDATENHFTDTPVLTDANLSGKGKY
LHITSNNTIYGSQYPELPKIKRVPLVADMTSELLSRKINVKDFGIIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPVLL
DYSVMVKNQSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKANLIYDFIDSSSLYTCPVQKRSRSKMNVVFLLRD
KNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLAGVQKLVSFMKEFESKT

Sequences:

>Translated_375_residues
MIPNLPFVTLSLMYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREPLFEDVIKKAEILLRELLDLE
DDYSVAFFSGGATLHFSALPLNLLKEGESFDIAHTGIWTKKAWEEGLKFNEVNIIHDATENHFTDTPVLTDANLSGKGKY
LHITSNNTIYGSQYPELPKIKRVPLVADMTSELLSRKINVKDFGIIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPVLL
DYSVMVKNQSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKANLIYDFIDSSSLYTCPVQKRSRSKMNVVFLLRD
KNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLAGVQKLVSFMKEFESKT
>Mature_375_residues
MIPNLPFVTLSLMYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREPLFEDVIKKAEILLRELLDLE
DDYSVAFFSGGATLHFSALPLNLLKEGESFDIAHTGIWTKKAWEEGLKFNEVNIIHDATENHFTDTPVLTDANLSGKGKY
LHITSNNTIYGSQYPELPKIKRVPLVADMTSELLSRKINVKDFGIIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPVLL
DYSVMVKNQSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKANLIYDFIDSSSLYTCPVQKRSRSKMNVVFLLRD
KNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLAGVQKLVSFMKEFESKT

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=44.3213296398892, Blast_Score=314, Evalue=9e-86,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=39.6067415730337, Blast_Score=262, Evalue=3e-70,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=44.4134078212291, Blast_Score=306, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=39.7222222222222, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6324758, Length=393, Percent_Identity=39.9491094147583, Blast_Score=269, Evalue=7e-73,
Organism=Drosophila melanogaster, GI21356589, Length=358, Percent_Identity=40.2234636871508, Blast_Score=267, Evalue=1e-71,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 41948; Mature: 41948

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPNLPFVTLSLMYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREP
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
LFEDVIKKAEILLRELLDLEDDYSVAFFSGGATLHFSALPLNLLKEGESFDIAHTGIWTK
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCHHHHCCCCCCEEEECCCCCH
KAWEEGLKFNEVNIIHDATENHFTDTPVLTDANLSGKGKYLHITSNNTIYGSQYPELPKI
HHHHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCEEECCCCCCCCCC
KRVPLVADMTSELLSRKINVKDFGIIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPVLL
CCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEE
DYSVMVKNQSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKANLIYDFIDSSSLY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCEE
TCPVQKRSRSKMNVVFLLRDKNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLAG
ECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHH
VQKLVSFMKEFESKT
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MIPNLPFVTLSLMYLFQERIYNFGAGPAMLPNEVMEIAAAEFLNYKGSGMSVMEVSHREP
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
LFEDVIKKAEILLRELLDLEDDYSVAFFSGGATLHFSALPLNLLKEGESFDIAHTGIWTK
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCHHHHCCCCCCEEEECCCCCH
KAWEEGLKFNEVNIIHDATENHFTDTPVLTDANLSGKGKYLHITSNNTIYGSQYPELPKI
HHHHHCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCEEECCCCCCCCCC
KRVPLVADMTSELLSRKINVKDFGIIFAGAQKNIGPSGLSLAIIRNDLLGISGRKIPVLL
CCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEE
DYSVMVKNQSLYNTPSTYSIYIAKLVFEWLLKLGGIEAIEKVNEQKANLIYDFIDSSSLY
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCEE
TCPVQKRSRSKMNVVFLLRDKNLDSKFLDEAEKNGLHGLGGHRLVGGFRASIYNSMPLAG
ECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHH
VQKLVSFMKEFESKT
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA