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The map label for this gene is yfhR [C]

Identifier: 116326977

GI number: 116326977

Start: 167759

End: 168571

Strand: Reverse

Name: yfhR [C]

Synonym: LBL_0144

Alternate gene names: 116326977

Gene position: 168571-167759 (Counterclockwise)

Preceding gene: 116326978

Following gene: 116326972

Centisome position: 4.66

GC content: 39.61

Gene sequence:

>813_bases
ATGATTCCCATTTTTATATTCTTATTATCCGCTATTTTCCTGGTTTTGTTTCTCGTTTGGTGGAACCAAGACAGGCTGAT
TTTTTTTCCGGAAAAACTTCCCGAAAATTTCGTATTCCGGTTTCCGAACGAGTTTCAGGAAATCAAACTCAATACTCCCG
ACGGAGAAATAAGTTACGGACTTTATTTCCCATCCAAAAGTAACATTTCTAAGAAAACGGTTTTATTCTTTCATGGAAAT
GCGGGAAGCCTGAGAACTTGGGGAAGAATTTGTGAAGACTTTCTTCCCTTCGGATGGAATATTCTAATTACCGACTACCG
AGGATATGGAAAGAATTCGGGAAGTATTTCCGAAAAATCGCTGAATGAAGATGCCGAGTTGTGGCTGAATTACGTACTTC
AGGAAATTAAGGTTCCTAGAAACAAGATCGTAATCTACGGTCGTTCCATTGGCACAGGAGTTGCGGCGAACTTAGCTTTT
GAGAATCCGGACCTTGATTTATTTTTAGAGACCCCATTTACTGATTTGCCAACTCTGGCGCGAAATTACTATCCGTTCCT
ACAAACTTGGATGTTACGTTTTCAATTTCGGAACCTGAGCAAATTGGAAACCGTACGCTCTAAAATCAGGATTTTCCACG
GAACGGAAGATGAGATCATTCCATATTCAAATTCGGAAATCATATTCAAAAAATTGAAAGAACGAAATCAAGATGTGATT
CTTTTTACGATCCCAAACGGCTCGCATAACGACCTTGCTCTTTATCCGGAATATCGCCGGGCATTGAAAAAAAGTCTAGA
TGAGATCCGATAA

Upstream 100 bases:

>100_bases
AGGTCAAAGAAAACTTGTTCTACAGATTTTTGACGTATATGGAAAAGAGCTTTGGAAAAAAGAAATCCTTCCAACCCCTT
AATGTTCTATGAAACGATCT

Downstream 100 bases:

>100_bases
AAGATCGATTTAAAAGTATTCTGGGAAAAGAACTTTGAGTTTTTTTACGGTTTCCGGATTTCTTTTTTCAGGCGCCGTGA
TGATCGAATATCGGGTACTG

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIPIFIFLLSAIFLVLFLVWWNQDRLIFFPEKLPENFVFRFPNEFQEIKLNTPDGEISYGLYFPSKSNISKKTVLFFHGN
AGSLRTWGRICEDFLPFGWNILITDYRGYGKNSGSISEKSLNEDAELWLNYVLQEIKVPRNKIVIYGRSIGTGVAANLAF
ENPDLDLFLETPFTDLPTLARNYYPFLQTWMLRFQFRNLSKLETVRSKIRIFHGTEDEIIPYSNSEIIFKKLKERNQDVI
LFTIPNGSHNDLALYPEYRRALKKSLDEIR

Sequences:

>Translated_270_residues
MIPIFIFLLSAIFLVLFLVWWNQDRLIFFPEKLPENFVFRFPNEFQEIKLNTPDGEISYGLYFPSKSNISKKTVLFFHGN
AGSLRTWGRICEDFLPFGWNILITDYRGYGKNSGSISEKSLNEDAELWLNYVLQEIKVPRNKIVIYGRSIGTGVAANLAF
ENPDLDLFLETPFTDLPTLARNYYPFLQTWMLRFQFRNLSKLETVRSKIRIFHGTEDEIIPYSNSEIIFKKLKERNQDVI
LFTIPNGSHNDLALYPEYRRALKKSLDEIR
>Mature_270_residues
MIPIFIFLLSAIFLVLFLVWWNQDRLIFFPEKLPENFVFRFPNEFQEIKLNTPDGEISYGLYFPSKSNISKKTVLFFHGN
AGSLRTWGRICEDFLPFGWNILITDYRGYGKNSGSISEKSLNEDAELWLNYVLQEIKVPRNKIVIYGRSIGTGVAANLAF
ENPDLDLFLETPFTDLPTLARNYYPFLQTWMLRFQFRNLSKLETVRSKIRIFHGTEDEIIPYSNSEIIFKKLKERNQDVI
LFTIPNGSHNDLALYPEYRRALKKSLDEIR

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI71051602, Length=200, Percent_Identity=33, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI71051600, Length=200, Percent_Identity=33, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI151301175, Length=209, Percent_Identity=30.622009569378, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194306564, Length=199, Percent_Identity=29.6482412060301, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI194306562, Length=200, Percent_Identity=29.5, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI109689718, Length=175, Percent_Identity=27.4285714285714, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI24308097, Length=175, Percent_Identity=27.4285714285714, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI226510965, Length=260, Percent_Identity=23.8461538461538, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988362, Length=199, Percent_Identity=31.1557788944724, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17532877, Length=218, Percent_Identity=27.9816513761468, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17566318, Length=215, Percent_Identity=24.6511627906977, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71985392, Length=139, Percent_Identity=31.6546762589928, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=200, Percent_Identity=29, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362521, Length=220, Percent_Identity=30.9090909090909, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281362519, Length=220, Percent_Identity=30.9090909090909, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571878, Length=220, Percent_Identity=30.9090909090909, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137566, Length=284, Percent_Identity=24.2957746478873, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 31704; Mature: 31704

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIFIFLLSAIFLVLFLVWWNQDRLIFFPEKLPENFVFRFPNEFQEIKLNTPDGEISYG
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCEEEEEECCCCCEEEE
LYFPSKSNISKKTVLFFHGNAGSLRTWGRICEDFLPFGWNILITDYRGYGKNSGSISEKS
EECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHH
LNEDAELWLNYVLQEIKVPRNKIVIYGRSIGTGVAANLAFENPDLDLFLETPFTDLPTLA
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHH
RNYYPFLQTWMLRFQFRNLSKLETVRSKIRIFHGTEDEIIPYSNSEIIFKKLKERNQDVI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCEECCCCCHHHHHHHHHCCCCEE
LFTIPNGSHNDLALYPEYRRALKKSLDEIR
EEEECCCCCCCEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPIFIFLLSAIFLVLFLVWWNQDRLIFFPEKLPENFVFRFPNEFQEIKLNTPDGEISYG
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCCEEEEEECCCCCEEEE
LYFPSKSNISKKTVLFFHGNAGSLRTWGRICEDFLPFGWNILITDYRGYGKNSGSISEKS
EECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHH
LNEDAELWLNYVLQEIKVPRNKIVIYGRSIGTGVAANLAFENPDLDLFLETPFTDLPTLA
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCHHHHH
RNYYPFLQTWMLRFQFRNLSKLETVRSKIRIFHGTEDEIIPYSNSEIIFKKLKERNQDVI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCEECCCCCHHHHHHHHHCCCCEE
LFTIPNGSHNDLALYPEYRRALKKSLDEIR
EEEECCCCCCCEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]