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The map label for this gene is plsB [H]

Identifier: 116326945

GI number: 116326945

Start: 123345

End: 125768

Strand: Direct

Name: plsB [H]

Synonym: LBL_0111

Alternate gene names: 116326945

Gene position: 123345-125768 (Clockwise)

Preceding gene: 116326943

Following gene: 116326948

Centisome position: 3.41

GC content: 40.06

Gene sequence:

>2424_bases
ATGGAAAAAATAAAATCATCTGCAATTATATCTGCTAATATCGCAGTTTTGGGAGGCGGGCCGATGGGGATCTATCTCTC
CACGTATCTTTCTCCTAAGGCAAAAGAAATTTTTCTTTGGTACGATGATCGGAAAAAAGCCGCAAAAATCGAAAAAGAAA
GAATAGCCTCGGTTCTCGAAGATTCAATCGCGCTTCCTGAGAATGTTCACGTCAAAAGCGAATTTGACTTTTTAAAAAGC
GGTTCTTGGATCCTTGTGATAGCGGTGCCTTCGAGATTGATGGAAGGAATTTTGGATGAATTGATCAAAATTCTGGATAA
AAATTCCTCCCATTATGTCTTTGCGTTTACGAAAGGACTTTTATCTATCTCCACAAGGAGAAAAACAAATTGCATTACAT
ATTCTGAATATATATATAAACTTTCCGTTACGGGAGAATTAAAAAATATCGAATACACCGCGGTTAACGGCCCGAATATT
CTGGGAGAATTAAAACGGGGTCATCATAGTTTTTATTGTTTGGCTTCTTCCGGAACTCAATCGGTCGAAATTTTTGAAAC
GTTATTCGGCGATTCTCGTAGTCATACCAAAACATACGAAGATCTCATGGGCTTAGAAGTGTTCGGGGTGATGAAAAATC
CGATCGCAATCGCTTGCGGAATCGCTTCGGGAATTCCCGAATGCGGAAGTAATTTTGAAGGAGAGCTCATCAGCCTCGGT
TATTCGGAAATTATTACTCTTTTGGAAGCGCTCGGAATTCCTACCAGACCTGTACAGGAATACGGCCTTGCGGATTTGAT
TGCTTCTTGCACTTCCCGTTATAGTCGAAACAAAGCATACGGTCATAGATTTGTACATAAATTGATTTCCGGGGAAGACC
GGCCTAATCTGATTGAAAGAATCGAATTGTTTTTTAATCCTGCCGAGTTTATTCAAAAAGAAGTCAGTCAGAGCGAAAGC
CACGTAGAGGGAGCTTTTGCGCTTGCTTCGATTATTTCTTTGGCGGAGGAAAAGGATGTCGATATTCCACTCTATAGTAT
TCTTTTTCAAATACTTACTAGGAAGGTTTCTCCGACAGAATTGATTCGTTTCGTTTCCAAGTCTACTTCCGACGAGGTTC
GTCACATTTCTAAAACCACCACAAAACGCTCCGGCTTGGGAACGGCTTCCGGTAAAAAGTTTCAGGAAGCATTGAGTAAA
AATGTATTAAGACATATCAACAGTCAACCGGGAATGACGGAGCGTATCGTTAAACAATCCTCGCTTCTTGTGAAATCGTT
GGAAAAAAGGTATAAAGAAGCGGAAGAATCCAAAGATATTACGGATCTTCTGCAAATCCCAAAAGAGATACAGCTTTGGA
ACGAGGTGGAAAAGAAGTTTCAGGAAAAGGGAAATAAGGATCTAACAAGAATATTAGATTTTTATGTTTCTGAAATTGCA
GATGATTACAAGCCGTTCTTGCGCGATACACTCATAAATCTGATCATCCCAATTCGTTACATTTTAAACGGCTTTAAATC
GGGAACTGGATTGCCTAAGATTGGCGGTTGTGTCAAGGAAGTGAAAGCTCTTGCTTCGAGATACGATATTCTTTATACAC
CGACTCACAGATCGCATTTGGATTCGATAGAAGTCGCTTTCGGTTTAAAATGGCTTGGACTTCCAGTGCCACGATATGCC
GCCGATAAAAAGGTAATGGCTACCCCTGGACTTGCTAACGTATTGAAGTCCCTCGGCGCTTACATGGTGGATAGAAAAAG
AAATCGGAATATTCTATATTTGGAATGTTTGACACAGTATTCTACGATGATGTTGGAGGCCGGAATTCCGACCTTGGTGT
ATCCGGAAGGAACTCGTTCTCGAACGGGAGGTATTCTTCCGATTAAAACCGGAATTTTATCCACTTCCGTAGATGCCTAT
AAACATACCGGCTCCGAAGTTATCATAGTTCCGATTGTGTTATCTTATGAAAACGTTCCGGAGGATGAGGAGTTTTGCGG
AAAAGGTAAGAAGTCCGGCTTTAGGGATTTCTTCTATAAGAGAAAAGAAGTATATATGGATCTTTGCGAACCGATTCCAG
TTTCAAGATATATACATGAAGAAGATCCGGTGGGAGTGATCGGATTTGAAATTACACAAGGTTGGAGAAAATACAGGAGA
ATTTTACCAAATCAACTTGTAGCGCGTTTGATCGTGGAAACGGGAACGGAAGTAAAGATGGACGAGTTGAGGAATTTAAT
TAAGGAAACGATTCTGACTAAAAAAGGAAATTATCTCATTCGAGATTCCGACGAAATTTTAAAACGAGGGCTTAAGATTT
TAAAACAAAGAAAGATAGTCTTTTTGGAGAATGAGAACGTAAAGGTATTGGATCATGATCTGATCCAATATTATGCAAAT
ATGTGTGTGGACGAAATGTCTTAG

Upstream 100 bases:

>100_bases
ACTCTCTTGTGATTTGTCGGTTAGGCAACCCGGAAAAAGAAAGCGAAAGATCCGTTTTCTGATTGTTTCCCGAATTCTTA
GCGTCTCAATAGCAATCAGA

Downstream 100 bases:

>100_bases
AGCCGTCTCAAAACCTTAGGAATGTAGGAGCTATTACAATCTTAAACGACAGGAAAAACCTTCAATACGACGGTTTCTGT
GGGAACTTCCACATTCAGAG

Product: bifunctional glycerol-3-phosphate dehydrogenase/glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MEKIKSSAIISANIAVLGGGPMGIYLSTYLSPKAKEIFLWYDDRKKAAKIEKERIASVLEDSIALPENVHVKSEFDFLKS
GSWILVIAVPSRLMEGILDELIKILDKNSSHYVFAFTKGLLSISTRRKTNCITYSEYIYKLSVTGELKNIEYTAVNGPNI
LGELKRGHHSFYCLASSGTQSVEIFETLFGDSRSHTKTYEDLMGLEVFGVMKNPIAIACGIASGIPECGSNFEGELISLG
YSEIITLLEALGIPTRPVQEYGLADLIASCTSRYSRNKAYGHRFVHKLISGEDRPNLIERIELFFNPAEFIQKEVSQSES
HVEGAFALASIISLAEEKDVDIPLYSILFQILTRKVSPTELIRFVSKSTSDEVRHISKTTTKRSGLGTASGKKFQEALSK
NVLRHINSQPGMTERIVKQSSLLVKSLEKRYKEAEESKDITDLLQIPKEIQLWNEVEKKFQEKGNKDLTRILDFYVSEIA
DDYKPFLRDTLINLIIPIRYILNGFKSGTGLPKIGGCVKEVKALASRYDILYTPTHRSHLDSIEVAFGLKWLGLPVPRYA
ADKKVMATPGLANVLKSLGAYMVDRKRNRNILYLECLTQYSTMMLEAGIPTLVYPEGTRSRTGGILPIKTGILSTSVDAY
KHTGSEVIIVPIVLSYENVPEDEEFCGKGKKSGFRDFFYKRKEVYMDLCEPIPVSRYIHEEDPVGVIGFEITQGWRKYRR
ILPNQLVARLIVETGTEVKMDELRNLIKETILTKKGNYLIRDSDEILKRGLKILKQRKIVFLENENVKVLDHDLIQYYAN
MCVDEMS

Sequences:

>Translated_807_residues
MEKIKSSAIISANIAVLGGGPMGIYLSTYLSPKAKEIFLWYDDRKKAAKIEKERIASVLEDSIALPENVHVKSEFDFLKS
GSWILVIAVPSRLMEGILDELIKILDKNSSHYVFAFTKGLLSISTRRKTNCITYSEYIYKLSVTGELKNIEYTAVNGPNI
LGELKRGHHSFYCLASSGTQSVEIFETLFGDSRSHTKTYEDLMGLEVFGVMKNPIAIACGIASGIPECGSNFEGELISLG
YSEIITLLEALGIPTRPVQEYGLADLIASCTSRYSRNKAYGHRFVHKLISGEDRPNLIERIELFFNPAEFIQKEVSQSES
HVEGAFALASIISLAEEKDVDIPLYSILFQILTRKVSPTELIRFVSKSTSDEVRHISKTTTKRSGLGTASGKKFQEALSK
NVLRHINSQPGMTERIVKQSSLLVKSLEKRYKEAEESKDITDLLQIPKEIQLWNEVEKKFQEKGNKDLTRILDFYVSEIA
DDYKPFLRDTLINLIIPIRYILNGFKSGTGLPKIGGCVKEVKALASRYDILYTPTHRSHLDSIEVAFGLKWLGLPVPRYA
ADKKVMATPGLANVLKSLGAYMVDRKRNRNILYLECLTQYSTMMLEAGIPTLVYPEGTRSRTGGILPIKTGILSTSVDAY
KHTGSEVIIVPIVLSYENVPEDEEFCGKGKKSGFRDFFYKRKEVYMDLCEPIPVSRYIHEEDPVGVIGFEITQGWRKYRR
ILPNQLVARLIVETGTEVKMDELRNLIKETILTKKGNYLIRDSDEILKRGLKILKQRKIVFLENENVKVLDHDLIQYYAN
MCVDEMS
>Mature_807_residues
MEKIKSSAIISANIAVLGGGPMGIYLSTYLSPKAKEIFLWYDDRKKAAKIEKERIASVLEDSIALPENVHVKSEFDFLKS
GSWILVIAVPSRLMEGILDELIKILDKNSSHYVFAFTKGLLSISTRRKTNCITYSEYIYKLSVTGELKNIEYTAVNGPNI
LGELKRGHHSFYCLASSGTQSVEIFETLFGDSRSHTKTYEDLMGLEVFGVMKNPIAIACGIASGIPECGSNFEGELISLG
YSEIITLLEALGIPTRPVQEYGLADLIASCTSRYSRNKAYGHRFVHKLISGEDRPNLIERIELFFNPAEFIQKEVSQSES
HVEGAFALASIISLAEEKDVDIPLYSILFQILTRKVSPTELIRFVSKSTSDEVRHISKTTTKRSGLGTASGKKFQEALSK
NVLRHINSQPGMTERIVKQSSLLVKSLEKRYKEAEESKDITDLLQIPKEIQLWNEVEKKFQEKGNKDLTRILDFYVSEIA
DDYKPFLRDTLINLIIPIRYILNGFKSGTGLPKIGGCVKEVKALASRYDILYTPTHRSHLDSIEVAFGLKWLGLPVPRYA
ADKKVMATPGLANVLKSLGAYMVDRKRNRNILYLECLTQYSTMMLEAGIPTLVYPEGTRSRTGGILPIKTGILSTSVDAY
KHTGSEVIIVPIVLSYENVPEDEEFCGKGKKSGFRDFFYKRKEVYMDLCEPIPVSRYIHEEDPVGVIGFEITQGWRKYRR
ILPNQLVARLIVETGTEVKMDELRNLIKETILTKKGNYLIRDSDEILKRGLKILKQRKIVFLENENVKVLDHDLIQYYAN
MCVDEMS

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=147, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1790037, Length=344, Percent_Identity=26.1627906976744, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87082362, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988723, Length=139, Percent_Identity=31.6546762589928, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988728, Length=139, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357731, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864692, Length=184, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650754, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650752, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 91060; Mature: 91060

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIKSSAIISANIAVLGGGPMGIYLSTYLSPKAKEIFLWYDDRKKAAKIEKERIASVLE
CCCHHCCEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
DSIALPENVHVKSEFDFLKSGSWILVIAVPSRLMEGILDELIKILDKNSSHYVFAFTKGL
HHCCCCCCCEECCHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
LSISTRRKTNCITYSEYIYKLSVTGELKNIEYTAVNGPNILGELKRGHHSFYCLASSGTQ
HHHHCCCCCCCEEEEHEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCC
SVEIFETLFGDSRSHTKTYEDLMGLEVFGVMKNPIAIACGIASGIPECGSNFEGELISLG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCHHHCCCCCCCCEECC
YSEIITLLEALGIPTRPVQEYGLADLIASCTSRYSRNKAYGHRFVHKLISGEDRPNLIER
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHH
IELFFNPAEFIQKEVSQSESHVEGAFALASIISLAEEKDVDIPLYSILFQILTRKVSPTE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
LIRFVSKSTSDEVRHISKTTTKRSGLGTASGKKFQEALSKNVLRHINSQPGMTERIVKQS
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLLVKSLEKRYKEAEESKDITDLLQIPKEIQLWNEVEKKFQEKGNKDLTRILDFYVSEIA
HHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DDYKPFLRDTLINLIIPIRYILNGFKSGTGLPKIGGCVKEVKALASRYDILYTPTHRSHL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHC
DSIEVAFGLKWLGLPVPRYAADKKVMATPGLANVLKSLGAYMVDRKRNRNILYLECLTQY
CHHHHHHCCHHHCCCCCCHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
STMMLEAGIPTLVYPEGTRSRTGGILPIKTGILSTSVDAYKHTGSEVIIVPIVLSYENVP
HHHHHHCCCCEEECCCCCCCCCCCEEEEECCHHHHCHHHHHCCCCCEEEEEEEEECCCCC
EDEEFCGKGKKSGFRDFFYKRKEVYMDLCEPIPVSRYIHEEDPVGVIGFEITQGWRKYRR
CCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEHHHHHHHHHHHH
ILPNQLVARLIVETGTEVKMDELRNLIKETILTKKGNYLIRDSDEILKRGLKILKQRKIV
HCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCEE
FLENENVKVLDHDLIQYYANMCVDEMS
EEECCCCEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKIKSSAIISANIAVLGGGPMGIYLSTYLSPKAKEIFLWYDDRKKAAKIEKERIASVLE
CCCHHCCEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
DSIALPENVHVKSEFDFLKSGSWILVIAVPSRLMEGILDELIKILDKNSSHYVFAFTKGL
HHCCCCCCCEECCHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
LSISTRRKTNCITYSEYIYKLSVTGELKNIEYTAVNGPNILGELKRGHHSFYCLASSGTQ
HHHHCCCCCCCEEEEHEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCC
SVEIFETLFGDSRSHTKTYEDLMGLEVFGVMKNPIAIACGIASGIPECGSNFEGELISLG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCHHHCCCCCCCCEECC
YSEIITLLEALGIPTRPVQEYGLADLIASCTSRYSRNKAYGHRFVHKLISGEDRPNLIER
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHH
IELFFNPAEFIQKEVSQSESHVEGAFALASIISLAEEKDVDIPLYSILFQILTRKVSPTE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
LIRFVSKSTSDEVRHISKTTTKRSGLGTASGKKFQEALSKNVLRHINSQPGMTERIVKQS
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SLLVKSLEKRYKEAEESKDITDLLQIPKEIQLWNEVEKKFQEKGNKDLTRILDFYVSEIA
HHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DDYKPFLRDTLINLIIPIRYILNGFKSGTGLPKIGGCVKEVKALASRYDILYTPTHRSHL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHC
DSIEVAFGLKWLGLPVPRYAADKKVMATPGLANVLKSLGAYMVDRKRNRNILYLECLTQY
CHHHHHHCCHHHCCCCCCHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
STMMLEAGIPTLVYPEGTRSRTGGILPIKTGILSTSVDAYKHTGSEVIIVPIVLSYENVP
HHHHHHCCCCEEECCCCCCCCCCCEEEEECCHHHHCHHHHHCCCCCEEEEEEEEECCCCC
EDEEFCGKGKKSGFRDFFYKRKEVYMDLCEPIPVSRYIHEEDPVGVIGFEITQGWRKYRR
CCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEHHHHHHHHHHHH
ILPNQLVARLIVETGTEVKMDELRNLIKETILTKKGNYLIRDSDEILKRGLKILKQRKIV
HCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCEE
FLENENVKVLDHDLIQYYANMCVDEMS
EEECCCCEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]