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The map label for this gene is btuE-1 [H]

Identifier: 116326940

GI number: 116326940

Start: 119763

End: 120248

Strand: Direct

Name: btuE-1 [H]

Synonym: LBL_0106

Alternate gene names: 116326940

Gene position: 119763-120248 (Clockwise)

Preceding gene: 116326937

Following gene: 116326941

Centisome position: 3.31

GC content: 37.04

Gene sequence:

>486_bases
ATGACCCAAACATTATACGATTTAACGGCTACTTTGAATAGTGGTAAAGAGCAGAGATTGGAAGATTATAGGGGAAAGGT
TCTCTTAATCGTAAATACTGCGAGTGAATGTGCTTTTACTCCTCAATATGCGGGCCTGCAAAGTTTATACGGTAAATACA
AAACGGAAGGGTTAGAAATTCTCGGATTTCCTTGCGATCAGTTCAAACATCAGGAACCGGGTTCGGATGAGACGATTAAG
AATTTTTGCCAAAAAAACTATGGAGTTGAATTTCCGATTTTTAAAAAAATCAATGTGAATGGAGATAGCGCCCATCCGGT
GTTTCGGTTTTTGAGAAAGAAAGCTTCCGGATTTTTCGGAAACTCGATCAAATGGAATTTTACGAAGTTCTTGGTAGATA
AACAAGGAAATGTAATTAAACGTTATTCTCCCATTACCACGCCGGAAAAGATCGAAAAAGTTATCCAAGACCTTTTAAAA
AAATAA

Upstream 100 bases:

>100_bases
TAGAATTAAGTTTCTATAATGAAATGAACCTCGAAAATTTTTCTTGACTAAAAAATGTATCTTTTAAAATTAAATTGTGC
ACAATCTAAATAGAGGTTAA

Downstream 100 bases:

>100_bases
AAACCGACTTCATATCATAAAATGAAACAGGTTTTTTATGAGTACAAAAGATCTTTTTTTAGAAAATCAGATTTGTTTCC
CTCTTTATGCTTGTTCTAGG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTQTLYDLTATLNSGKEQRLEDYRGKVLLIVNTASECAFTPQYAGLQSLYGKYKTEGLEILGFPCDQFKHQEPGSDETIK
NFCQKNYGVEFPIFKKINVNGDSAHPVFRFLRKKASGFFGNSIKWNFTKFLVDKQGNVIKRYSPITTPEKIEKVIQDLLK
K

Sequences:

>Translated_161_residues
MTQTLYDLTATLNSGKEQRLEDYRGKVLLIVNTASECAFTPQYAGLQSLYGKYKTEGLEILGFPCDQFKHQEPGSDETIK
NFCQKNYGVEFPIFKKINVNGDSAHPVFRFLRKKASGFFGNSIKWNFTKFLVDKQGNVIKRYSPITTPEKIEKVIQDLLK
K
>Mature_160_residues
TQTLYDLTATLNSGKEQRLEDYRGKVLLIVNTASECAFTPQYAGLQSLYGKYKTEGLEILGFPCDQFKHQEPGSDETIKN
FCQKNYGVEFPIFKKINVNGDSAHPVFRFLRKKASGFFGNSIKWNFTKFLVDKQGNVIKRYSPITTPEKIEKVIQDLLKK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=45.8064516129032, Blast_Score=140, Evalue=6e-34,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=45.8064516129032, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=41.25, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=37.1069182389937, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=43.9393939393939, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI41406084, Length=185, Percent_Identity=36.2162162162162, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=34.6368715083799, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=31.3513513513514, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI33186887, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI6006001, Length=182, Percent_Identity=32.4175824175824, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788003, Length=155, Percent_Identity=45.1612903225806, Blast_Score=140, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=45.2229299363057, Blast_Score=149, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=43.0379746835443, Blast_Score=142, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=165, Percent_Identity=40.6060606060606, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=39.4904458598726, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=33.5365853658537, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=32.9268292682927, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71999642, Length=79, Percent_Identity=40.5063291139241, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=34.7368421052632, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507603, Length=100, Percent_Identity=36, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=158, Percent_Identity=54.4303797468354, Blast_Score=181, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6319721, Length=162, Percent_Identity=52.4691358024691, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=47.2049689440994, Blast_Score=150, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=43.6708860759494, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=43.125, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=43.125, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI85726443, Length=161, Percent_Identity=38.5093167701863, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18429; Mature: 18298

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLYDLTATLNSGKEQRLEDYRGKVLLIVNTASECAFTPQYAGLQSLYGKYKTEGLEI
CCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCEEE
LGFPCDQFKHQEPGSDETIKNFCQKNYGVEFPIFKKINVNGDSAHPVFRFLRKKASGFFG
ECCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC
NSIKWNFTKFLVDKQGNVIKRYSPITTPEKIEKVIQDLLKK
CCCCCCHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTLYDLTATLNSGKEQRLEDYRGKVLLIVNTASECAFTPQYAGLQSLYGKYKTEGLEI
CCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCEEE
LGFPCDQFKHQEPGSDETIKNFCQKNYGVEFPIFKKINVNGDSAHPVFRFLRKKASGFFG
ECCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC
NSIKWNFTKFLVDKQGNVIKRYSPITTPEKIEKVIQDLLKK
CCCCCCHHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]