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The map label for this gene is argM [C]

Identifier: 115353093

GI number: 115353093

Start: 3358731

End: 3360164

Strand: Direct

Name: argM [C]

Synonym: Bamb_3042

Alternate gene names: 115353093

Gene position: 3358731-3360164 (Clockwise)

Preceding gene: 115353092

Following gene: 115353094

Centisome position: 94.44

GC content: 66.25

Gene sequence:

>1434_bases
ATGACGTACCGCAACGAATCAGCGTGGATCCAGCCGGCCGCACCGGCCGTCGCACCGCGCACGACGCAGGCCCGCTCGAC
CGCCGAATACCGCGCGCTCGACGCCGCACACCACATTCACCCGTTCTCGGACATGGGCGCGCTCAATCGCGCGGGCAGCC
GCGTGATCGTGAAGGCCGACGGCGTCTACCTGTGGGACTCCGACGGCAACAAGGTGATCGACGGGATGGCCGGCCTCTGG
TGCGTGAACGTCGGCTACGGCCGCAAGGAACTCGCCGACGCCGCGTATCGCCAGCTGCAGGAACTGCCGTTCTACAACAC
GTTCTTCAAGACCACGCACCCGCCGATCATCGAACTGTCGGCGCTGCTCGCCGAAGTCACGCCCGCAGGCTTCAATCACT
TCTTCTATTGCAACAGCGGCTCGGAAGGCAACGACACCGTGCTGCGCGTCGTGCACCAGTACTGGCGCGTGCAGGGCCAG
CCGCAGAAGAAATACGTGATCTCGCGCAAGAACGGTTACCACGGCTCGACGATCGCGGGCGGCACGCTCGGCGGGATGGG
CTACATGCACGAGCAGATGCCGTCGAAGGTCGAGCACATCGTGCACATCGACCAGCCGTATTTCTTCGGCGAAGCGCAAG
CCGGCGAGACGCCCGAAGCGTTCGGCCTCGCCCGTGCGCAGCAGCTCGAGGCGAAGATCCTCGAACTCGGCGCGGAGAAC
GTCGCGGCGTTCATCGGCGAGCCGTTCCAGGGCGCCGGCGGCGTGATCTTCCCGCCGTCGACGTACTGGCCGGAAATCCA
GCGGATCTGCCGCAAGTACGACATCCTGCTCGTCGCCGACGAAGTGATCGGCGGCTTCGGCCGCACCGGCGAATGGTTCG
CGCACCAGCACTTCGGCTTCGAGCCGGACCTGATCACGATGGCCAAGGGCCTGACGTCGGGTTACGTGCCGATGGGTGCG
GTCGGGATTCACGAGCGCGTCGCGCGGCCGATCATCGACAACGGCGAATTCAATCACGGCCTGACCTACTCGGGGCATCC
GGTGGCGGCAGCCGTCGCGGTTGCGAACCTGAAGCTGCTGCGCGACGAAGGAATCGTCGAGCGCGTGAAGAACGACACGG
GCCCGTACTTCCAGGCGCTGATGCGCGAGACCTTCGCGCGTCACCCGATCGTCGGCGAGGTGCACGGCCACGGCCTCGTC
GCGAGCCTGCAGCTCGCCGAAGCGCCGGCCGAGCGTCGGCGCTTCGCGAACGGCGGCGACGTCGGCACGATCTGCCGCGA
CTTCTGCTTCAACGGCAACCTGATCATGCGCGCGACCGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGATCTCGCGTC
AGGAAATCGATGAACTCGTATCGAAGGCGAAGAAGGCCGTCGATGCGACCGCCCAGCAACTGGGCCTTTCGTAA

Upstream 100 bases:

>100_bases
TACGAAGCGTTCTTCCGCGTGATCAGCTCGTGGGAACGCCGTCATCTGCTGCTGCACGTGTAAGCGCGCGCACGAACGTA
CCAACGAATACGGAGGAAAC

Downstream 100 bases:

>100_bases
CGACCTTGCCTCCGGGCGTGCGGCGGGCGCCGCACGCCACCATCATCCAGGGGAATTCCACCATGCGTTCCAGCTTTCTT
CGCCAAGCCTGTTCCGTTGC

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTYRNESAWIQPAAPAVAPRTTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLW
CVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPIIELSALLAEVTPAGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGQ
PQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAEN
VAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGA
VGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLV
ASLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKKAVDATAQQLGLS

Sequences:

>Translated_477_residues
MTYRNESAWIQPAAPAVAPRTTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLW
CVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPIIELSALLAEVTPAGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGQ
PQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAEN
VAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGA
VGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLV
ASLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKKAVDATAQQLGLS
>Mature_476_residues
TYRNESAWIQPAAPAVAPRTTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLWC
VNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPIIELSALLAEVTPAGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGQP
QKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENV
AAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAV
GIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLVA
SLQLAEAPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKKAVDATAQQLGLS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=458, Percent_Identity=25.9825327510917, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24119277, Length=362, Percent_Identity=29.5580110497238, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI37574042, Length=379, Percent_Identity=28.2321899736148, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442705, Length=376, Percent_Identity=28.4574468085106, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=26.463700234192, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI226442709, Length=332, Percent_Identity=28.0120481927711, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=30.8695652173913, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=22.7166276346604, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=22.7166276346604, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=22.7166276346604, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788044, Length=403, Percent_Identity=28.287841191067, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786991, Length=453, Percent_Identity=28.9183222958057, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=25.8536585365854, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=26.5060240963855, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789016, Length=359, Percent_Identity=25.9052924791086, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787560, Length=360, Percent_Identity=28.8888888888889, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=24.773413897281, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=427, Percent_Identity=26.463700234192, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=29.0249433106576, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=371, Percent_Identity=26.4150943396226, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=497, Percent_Identity=22.7364185110664, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323470, Length=456, Percent_Identity=27.4122807017544, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6324432, Length=430, Percent_Identity=24.8837209302326, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324386, Length=366, Percent_Identity=30.0546448087432, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21357415, Length=442, Percent_Identity=26.4705882352941, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=29.1954022988506, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=28.7410926365796, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=25.5172413793103, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281366494, Length=350, Percent_Identity=24.5714285714286, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667139, Length=350, Percent_Identity=24.5714285714286, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667143, Length=350, Percent_Identity=24.5714285714286, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52265; Mature: 52134

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRNESAWIQPAAPAVAPRTTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKAD
CCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEC
GVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPIIELS
CEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHH
ALLAEVTPAGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGQPQKKYVISRKNGYHGSTIAG
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
GTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAEN
CCCCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHH
VAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGF
HHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCC
EPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLL
CCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAEAPAERRRFANGGD
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCHHHHHCCCCCC
VGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKKAVDATAQQLGLS
HHHHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRNESAWIQPAAPAVAPRTTQARSTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKAD
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEC
GVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQLQELPFYNTFFKTTHPPIIELS
CEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHH
ALLAEVTPAGFNHFFYCNSGSEGNDTVLRVVHQYWRVQGQPQKKYVISRKNGYHGSTIAG
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
GTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAEN
CCCCCHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHH
VAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGF
HHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCC
EPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLL
CCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAEAPAERRRFANGGD
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCHHHHHCCCCCC
VGTICRDFCFNGNLIMRATGDRMLLSPPLVISRQEIDELVSKAKKAVDATAQQLGLS
HHHHHHHHHCCCCEEEEECCCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]