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The map label for this gene is dapA [H]

Identifier: 115353044

GI number: 115353044

Start: 3309738

End: 3310631

Strand: Direct

Name: dapA [H]

Synonym: Bamb_2993

Alternate gene names: 115353044

Gene position: 3309738-3310631 (Clockwise)

Preceding gene: 115353041

Following gene: 115353046

Centisome position: 93.06

GC content: 72.15

Gene sequence:

>894_bases
ATGCACACACGTTTCGAAGGTATCTGGCTGCCAATCATCACGCCGTTCCATGACGGCGAGGTCGACCACGGCGCGCTCGC
GCGACTCGCGCGTCACTATGCGGCGGCGGGTATCGCGGGGTTCGTCGCAGGCGCGACGACCGGTGAAGGCGTGCTGCTCG
ACGCGCGCGAACAGGACGCCGTGTTCGCGACGTTGCGCGATGCGGTGCCCGGCCTGCCGGTCGTCGTCGGGCTCACCGCG
AGCGCGACGCACTTCGCGGCCGCCCGCGCACGCGAGCTCGCCGCGCTGCGGCCCGACGGGCTGCTCGTCACGCCGCCCGT
CTACGTTCGGCCGACGCAGGACGGCATCCGCCGCCACGTGGAAGCGATCGTCGACGCGGCCGACCTGCCGGTCCTCGTCT
ACAACATCCCGTACCGCACCGGCGTGAACGTCGAACTGGAGACGCTGCAGGCGCTCGCGCGCGACCCGCGCGTCGCGGGC
ATCAAGGAATGCGGCGGCACGCTCGACCGAATGAGCCGGCTCGTGCACGACACCCCGCTCGCGATCCTTTCCGGCGACGA
CAACCAGAACTTCGCTGCGCTGTGTGCCGGCGCGCATGGCGCAATCGCGAGCAGCGCGCATGTGCTGCCCGAGTGGCACG
TGCGCATCCATGCGCTGCTGCGCGACGGCCGGCTCGCCGACGCGCGCGAGCTGTCGGTCGCGCTGCAGCCGCTGGTCGCG
GCGCTGTTCGCGGAGCCGAATCCGGCCCCGGTGAAGGCGGTGCTGGCCGCGCAGGGGTGGTGCGAGGACGGGTTGCGGCT
GCCGTTCGTGCCGGCGAGCGACGGCTTGCGGGGCAGGCTGGCCGAAATTCTGGCCACGCTCGGAGCAATCGCGCCGGACA
GCGCCGCCGCATAG

Upstream 100 bases:

>100_bases
ATGCCCGCAGGTCGTTTCTTTTCCTCGCTCGCACGCCTCGCTCCGGCACATCGCCGGCGGAACGGTTCCTTCCCACTCCG
TTTCCACCATGAGGCTTTGC

Downstream 100 bases:

>100_bases
GCCGCGACGCGACGCGCGGCTCGGACAATGGGCGCTGCTGACGAAGCGCTCATCCGCACGCCTGATCGCTCCATTCGGCC
GATCGGCAGAGGCGTGCCGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MHTRFEGIWLPIITPFHDGEVDHGALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPGLPVVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGTLDRMSRLVHDTPLAILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARELSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRGRLAEILATLGAIAPDSAAA

Sequences:

>Translated_297_residues
MHTRFEGIWLPIITPFHDGEVDHGALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPGLPVVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGTLDRMSRLVHDTPLAILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARELSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRGRLAEILATLGAIAPDSAAA
>Mature_297_residues
MHTRFEGIWLPIITPFHDGEVDHGALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDAVFATLRDAVPGLPVVVGLTA
SATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHVEAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAG
IKECGGTLDRMSRLVHDTPLAILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARELSVALQPLVA
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRGRLAEILATLGAIAPDSAAA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=233, Percent_Identity=26.6094420600858, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1788823, Length=279, Percent_Identity=36.2007168458781, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789620, Length=262, Percent_Identity=27.4809160305344, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082415, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786463, Length=232, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31224; Mature: 31224

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRFEGIWLPIITPFHDGEVDHGALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAVPGLPVVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAGIKECGGTLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCE
AILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARELSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHEEEHHHCCCCCCHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRGRLAEILATLGAIAPDSAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHTRFEGIWLPIITPFHDGEVDHGALARLARHYAAAGIAGFVAGATTGEGVLLDAREQDA
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
VFATLRDAVPGLPVVVGLTASATHFAAARARELAALRPDGLLVTPPVYVRPTQDGIRRHV
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHH
EAIVDAADLPVLVYNIPYRTGVNVELETLQALARDPRVAGIKECGGTLDRMSRLVHDTPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCE
AILSGDDNQNFAALCAGAHGAIASSAHVLPEWHVRIHALLRDGRLADARELSVALQPLVA
EEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHEEEHHHCCCCCCHHHHHHHHHHHHH
ALFAEPNPAPVKAVLAAQGWCEDGLRLPFVPASDGLRGRLAEILATLGAIAPDSAAA
HHHCCCCCCCHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]