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The map label for this gene is moeB [H]

Identifier: 115352965

GI number: 115352965

Start: 3212252

End: 3213004

Strand: Direct

Name: moeB [H]

Synonym: Bamb_2914

Alternate gene names: 115352965

Gene position: 3212252-3213004 (Clockwise)

Preceding gene: 115352964

Following gene: 115352973

Centisome position: 90.32

GC content: 69.85

Gene sequence:

>753_bases
ATGAACGACGATCAACTCCTTCGCTACTCCCGCCACATCCTCGTCGACGAAATCGGCATCGAGGCGCAGCAGCGCTTCCT
CGACGCGCATGCGCTCGTCGTCGGCGCGGGCGGGCTCGGCTCGCCGGCCGCGATGTATCTGGCGGCCTCCGGCGTCGGCA
CGATCACGCTGGTCGACGCCGACACGGTCGATCTCACGAACCTGCAGCGGCAGATCCTGCACGCGACGGCCTCCGTCGGG
CGCAGCAAGGTCGAATCGGGGCGCGACACGCTCGCGCGGCTGAACCCGGAAGTGACCGTGCATGCGGTCGCGGCGCGCGT
CGACGATGCGTGGCTCGACGAACACGTGCCGCGGGCGGGCGTCGTGCTCGACTGCACCGACAACTTCGCGACACGCCATG
CGATCAACCGCGCGTGCGTCGCGCACGGCGTGCCGCTCGTGTCGGGCGCCGCGCTGCGCTTCGACGGCCAGATCAGCACG
TTCGACTTCCGCGACCCGGCCGCGCCCTGCTACGCGTGCGTGTTTCCGGAAGACCAGCCGTTCGAGGAAGTCGCGTGCGC
GACGATGGGCGTGTTCGCGCCGACGGTCGGGATCATCGGCGCGATGCAGGCCGCCGAAGCGCTGCGCGTGATCGGCGCGA
TCGGCACGACGCTCAACGGCCGGCTGATGATGCTCGATTCGCTGCGGATGGAATGGACGACGATGAAGATCGCGCGCCAG
GCCGACTGCCCCGTGTGCCAGGGCCGGCACTGA

Upstream 100 bases:

>100_bases
CCGGCCGGCATCCGACGGGCCATCGCGGGAAGACCGCGATGGCCCGTTTTTCATGCGCGCCTAAAATAACGCTACGTCCG
CCGCCTCGCTCACGACTCCC

Downstream 100 bases:

>100_bases
CGCGCGCGATGCATGCGCCGAACGGGCCGCATGCATGACCGTGACGTTTCGCTACTTTCGCGGCGGTTTCACGGCGCGGC
CCCGCGTCGCCTAGGCGGCC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHALVVGAGGLGSPAAMYLAASGVGTITLVDADTVDLTNLQRQILHATASVG
RSKVESGRDTLARLNPEVTVHAVAARVDDAWLDEHVPRAGVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGAIGTTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCQGRH

Sequences:

>Translated_250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHALVVGAGGLGSPAAMYLAASGVGTITLVDADTVDLTNLQRQILHATASVG
RSKVESGRDTLARLNPEVTVHAVAARVDDAWLDEHVPRAGVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGAIGTTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCQGRH
>Mature_250_residues
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHALVVGAGGLGSPAAMYLAASGVGTITLVDADTVDLTNLQRQILHATASVG
RSKVESGRDTLARLNPEVTVHAVAARVDDAWLDEHVPRAGVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIST
FDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGAIGTTLNGRLMMLDSLRMEWTTMKIARQ
ADCPVCQGRH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=251, Percent_Identity=41.4342629482072, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI4885649, Length=173, Percent_Identity=30.0578034682081, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1787048, Length=249, Percent_Identity=43.7751004016064, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI87082356, Length=254, Percent_Identity=43.3070866141732, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1789177, Length=162, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=257, Percent_Identity=39.6887159533074, Blast_Score=196, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI193203301, Length=164, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=249, Percent_Identity=36.5461847389558, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320598, Length=169, Percent_Identity=26.6272189349112, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582879, Length=254, Percent_Identity=40.9448818897638, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24660640, Length=158, Percent_Identity=32.2784810126582, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573937, Length=159, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26737; Mature: 26737

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHALVVGAGGLGSPAAMYLAASGVGTITLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCCCHHHHEEEECCCCEEEEEEC
DTVDLTNLQRQILHATASVGRSKVESGRDTLARLNPEVTVHAVAARVDDAWLDEHVPRAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCCC
VVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQISTFDFRDPAAPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACATMGVFAPTVGIIGAMQAAEALRVIGAIGTTLNGRLMMLDSLRMEWTTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
ADCPVCQGRH
CCCCCCCCCC
>Mature Secondary Structure
MNDDQLLRYSRHILVDEIGIEAQQRFLDAHALVVGAGGLGSPAAMYLAASGVGTITLVDA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEEECCCCCCHHHHEEEECCCCEEEEEEC
DTVDLTNLQRQILHATASVGRSKVESGRDTLARLNPEVTVHAVAARVDDAWLDEHVPRAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHCCCCCC
VVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQISTFDFRDPAAPCYACVFPEDQP
EEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEEEECCCCCCCCEEEEECCCCCC
FEEVACATMGVFAPTVGIIGAMQAAEALRVIGAIGTTLNGRLMMLDSLRMEWTTMKIARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
ADCPVCQGRH
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]