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The map label for this gene is gpmA

Identifier: 115352963

GI number: 115352963

Start: 3209585

End: 3210331

Strand: Direct

Name: gpmA

Synonym: Bamb_2912

Alternate gene names: 115352963

Gene position: 3209585-3210331 (Clockwise)

Preceding gene: 115352957

Following gene: 115352964

Centisome position: 90.24

GC content: 66.67

Gene sequence:

>747_bases
ATGTACAAACTCGTTCTCATCCGCCACGGCGAATCGACGTGGAACAAGGAAAACCGCTTCACCGGCTGGGTCGACGTCGA
CCTGACCGAACAGGGTCGCAACGAGGCCTACCAGGCCGGCGAATTGCTCAAGGAGGCCGGCTACACGTTCGACATCGCGT
ACACGTCGGTGCTCAAGCGCGCGATCCGCACGCTGTGGCACGTGCAGGACCGGATGGACCTGATGTACCTGCCGGTCGTC
CACTCGTGGCGCCTGAACGAGCGCCACTACGGCGCGCTGTCGGGCCTGAACAAGGCGGAAACGGCCGCCAAGTTCGGCGA
CGACCAGGTGCTCGTGTGGCGCCGCAGCTACGACACGCCGCCGCCCGCACTCGAGCCGACCGACGAGCGCGCGCCGTTCA
ACGACCCGCGCTACGCGAAGGTGCCGCGCGAACAGCTGCCGCTCACCGAGTGCCTGAAGGACACGGTCGCGCGCGTGCTG
CCGCTGTGGAACGAATCGATCGCGCCGGCCGTCCGCTCGGGCAAGCAGGTGCTGATCGCCGCGCACGGCAACTCGCTGCG
CGCGCTGATCAAGTACCTCGACGGCATTTCGGACAGCGACATCGTCGGCCTGAACATCCCGAACGGCGTGCCGCTCGTGT
ATGAACTCGACGAAGACCTGAAGCCGATCCAGCACTACTACCTCGGCGACCAGGACGCGATCGCGAAGGCGCAGGCCGCC
GTCGCGAAGCAGGGCAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
AATCCGGCCATTATAAAATAACCGTCTTGCGCGATGGCGGACCCGGGCCGGGTACCGCGCGACGCGCCCCGCTTCCCTAT
CACTACCGACCGCAAGATCC

Downstream 100 bases:

>100_bases
CACCCGTCACGCCGGGCGGGCCGCGTCGCGCGGCCTGTTCGGGGCCCGCCCGCGCGCGCGGCGGCGCGAACCTTCGCGGC
CCCTGTGCTGTCGAATCCGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVV
HSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVRSGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPIQHYYLGDQDAIAKAQAA
VAKQGKAG

Sequences:

>Translated_248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVV
HSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVRSGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPIQHYYLGDQDAIAKAQAA
VAKQGKAG
>Mature_248_residues
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVV
HSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVL
PLWNESIAPAVRSGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPIQHYYLGDQDAIAKAQAA
VAKQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=252, Percent_Identity=57.1428571428571, Blast_Score=309, Evalue=2e-84,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=60.6425702811245, Blast_Score=300, Evalue=8e-82,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=59.0361445783133, Blast_Score=287, Evalue=5e-78,
Organism=Homo sapiens, GI4502445, Length=254, Percent_Identity=50.7874015748031, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI40353764, Length=254, Percent_Identity=50.7874015748031, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=62.962962962963, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1786970, Length=245, Percent_Identity=65.7142857142857, Blast_Score=330, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6322697, Length=249, Percent_Identity=54.2168674698795, Blast_Score=248, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6324516, Length=286, Percent_Identity=32.8671328671329, Blast_Score=150, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320183, Length=291, Percent_Identity=32.6460481099656, Blast_Score=142, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=52.8, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=52.8, Blast_Score=263, Evalue=8e-71,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=40.6374501992032, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=40.6374501992032, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=40.6374501992032, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27956; Mature: 27956

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH
AIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEECCEECCCCHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
PPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVRSGKQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEE
AHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPIQHYYLGDQDAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHH
VAKQGKAG
HHHCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLKEAGYTFDIAYTSVLKR
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH
AIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTP
HHHHHHHHHHCCCEEEECEECCEECCCCHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
PPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVRSGKQVLIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEE
AHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPIQHYYLGDQDAIAKAQAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHH
VAKQGKAG
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA