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The map label for this gene is fabF [H]

Identifier: 115352869

GI number: 115352869

Start: 3109544

End: 3110767

Strand: Direct

Name: fabF [H]

Synonym: Bamb_2818

Alternate gene names: 115352869

Gene position: 3109544-3110767 (Clockwise)

Preceding gene: 115352868

Following gene: 115352870

Centisome position: 87.43

GC content: 71.24

Gene sequence:

>1224_bases
GTGAAACCTCTGCTGCTCTCGCACTTCACCGCCACCAGCTGCATCGGCCGCGGCCTCGACGCGACCCTCGACGCGCTGCG
CCACGCGCGCGGCGCTCTCACGCCGTGCGACTTCGAACGCGCCGAACTCGACACCTGGATCGGCTCGGTGGACGGCGTCG
ATGCGCAGCCCGTGCGCGCGGATCTCTCCGATTTCGACTGCCGCAACAACCGCCTCGCGCAGCTCGGCCTCGTGCAGGAC
GGCTTCGACGCGCGCGTCGCGGCGGCCGTGTCGCGCCACGGCGCCGCCCGCGTCGGCGTGTTCATCGGCACGAGCACGTC
CGGCATCCTCGAGACCGAACGCGCGTACGAGCAACGCGATCCGGCGAGCGGCGCACTGCCCGCCGGGTTCCGCTATGCGC
ATACCCACAACCCGTATTCGGCGGCTGCATTCGTGCGTGCGTATTTCTCGCTGCGCGGGCCGGCGACGGCGATCTCGTCC
GCGTGTTCGTCCGGCGCGAAGGTATTCGGCTCCGCGCGCCGGATGATCGAAGCGGGGCTGATCGATGCGGCCGTCGTCGG
CGGCGTCGATTCGCTGTGCCTGACGACGCTGTACGGCTTCAATTCGCTCGAACTGTTGTCGCGCAAGCCGTGCCGGCCGT
TCGACGTCGCGCGAGACGGCATCTCGATCGGCGAGGCCGCCGCGTTCGCGCTGCTCGAACGCGTGCCGGAAACACGCGCC
GCGCTCGATGGCGACGCGATCCTGCTGCTCGGCGTCGGCGAATCGAGCGATGCGCATCATATGTCGTCGCCGCATCCGGA
CGGGCTCGGCGCACGCGTCGCGATCGAACAGGCGCTCGCATCGGCCGGCCTCGACGCGAGCGACATCGACTACGTGAACC
TGCACGGCACCGCGACGCCCAGCAACGATGCCGCCGAAAGCCGCGCCGTGGGCGCACTGCTCGCACGCACGCCGTGCAGC
TCGACGAAGGGGGCGACCGGTCACACGCTCGGCGCCGCCGGCGCGCTCGAAGCGGTCGTCGCCGCGCTCGCGCTGCGCGA
GCAGTTCGTGCCGGCCGGCGTCAACACGACGCAACCCGATCCGGCGCTGGCCGCCGACTACGTGCTCGCGAGCCGCGACG
CGCACCTGCGTGCGGTCCTGTCCAATTCGTTCGGCTTCGGCGGCACGAATTGCAGCCTGATCCTCGGCCGCGCCGAGCAC
GCCCGCCGCCGGGAGCCGACATGA

Upstream 100 bases:

>100_bases
GCCGGGCATGCTGGCACCCCCGTTTGATAAAATCTGACCATGCGCGGCGCGCCCGCCAGCCCTGCTGCGGCGCCCGTTCC
GGCCACCGGATGCGACCCTC

Downstream 100 bases:

>100_bases
CCGTCACCGCCTTCATCGAAAGTGTCGGCCTCATCGGGCCGGGACTGAACGACTGGCCGCACGCGGCCGACGTGCTCGCC
GGACGCACGCCCTATGCGAG

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGALTPCDFERAELDTWIGSVDGVDAQPVRADLSDFDCRNNRLAQLGLVQD
GFDARVAAAVSRHGAARVGVFIGTSTSGILETERAYEQRDPASGALPAGFRYAHTHNPYSAAAFVRAYFSLRGPATAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRKPCRPFDVARDGISIGEAAAFALLERVPETRA
ALDGDAILLLGVGESSDAHHMSSPHPDGLGARVAIEQALASAGLDASDIDYVNLHGTATPSNDAAESRAVGALLARTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDAHLRAVLSNSFGFGGTNCSLILGRAEH
ARRREPT

Sequences:

>Translated_407_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGALTPCDFERAELDTWIGSVDGVDAQPVRADLSDFDCRNNRLAQLGLVQD
GFDARVAAAVSRHGAARVGVFIGTSTSGILETERAYEQRDPASGALPAGFRYAHTHNPYSAAAFVRAYFSLRGPATAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRKPCRPFDVARDGISIGEAAAFALLERVPETRA
ALDGDAILLLGVGESSDAHHMSSPHPDGLGARVAIEQALASAGLDASDIDYVNLHGTATPSNDAAESRAVGALLARTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDAHLRAVLSNSFGFGGTNCSLILGRAEH
ARRREPT
>Mature_407_residues
MKPLLLSHFTATSCIGRGLDATLDALRHARGALTPCDFERAELDTWIGSVDGVDAQPVRADLSDFDCRNNRLAQLGLVQD
GFDARVAAAVSRHGAARVGVFIGTSTSGILETERAYEQRDPASGALPAGFRYAHTHNPYSAAAFVRAYFSLRGPATAISS
ACSSGAKVFGSARRMIEAGLIDAAVVGGVDSLCLTTLYGFNSLELLSRKPCRPFDVARDGISIGEAAAFALLERVPETRA
ALDGDAILLLGVGESSDAHHMSSPHPDGLGARVAIEQALASAGLDASDIDYVNLHGTATPSNDAAESRAVGALLARTPCS
STKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPDPALAADYVLASRDAHLRAVLSNSFGFGGTNCSLILGRAEH
ARRREPT

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=273, Percent_Identity=39.9267399267399, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI223972627, Length=160, Percent_Identity=40.625, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=29.7124600638978, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787337, Length=262, Percent_Identity=41.2213740458015, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI1788663, Length=257, Percent_Identity=34.2412451361868, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71983541, Length=269, Percent_Identity=34.5724907063197, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=35, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI212642053, Length=356, Percent_Identity=26.685393258427, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=308, Percent_Identity=24.025974025974, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320904, Length=290, Percent_Identity=36.551724137931, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24644341, Length=319, Percent_Identity=38.2445141065831, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24581345, Length=330, Percent_Identity=28.1818181818182, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI221330659, Length=316, Percent_Identity=27.8481012658228, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19920632, Length=316, Percent_Identity=27.8481012658228, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42232; Mature: 42232

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLLLSHFTATSCIGRGLDATLDALRHARGALTPCDFERAELDTWIGSVDGVDAQPVRA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
DLSDFDCRNNRLAQLGLVQDGFDARVAAAVSRHGAARVGVFIGTSTSGILETERAYEQRD
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
PASGALPAGFRYAHTHNPYSAAAFVRAYFSLRGPATAISSACSSGAKVFGSARRMIEAGL
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAAVVGGVDSLCLTTLYGFNSLELLSRKPCRPFDVARDGISIGEAAAFALLERVPETRA
HHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHH
ALDGDAILLLGVGESSDAHHMSSPHPDGLGARVAIEQALASAGLDASDIDYVNLHGTATP
HCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
SNDAAESRAVGALLARTPCSSTKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPD
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PALAADYVLASRDAHLRAVLSNSFGFGGTNCSLILGRAEHARRREPT
CHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECHHHHHCCCCC
>Mature Secondary Structure
MKPLLLSHFTATSCIGRGLDATLDALRHARGALTPCDFERAELDTWIGSVDGVDAQPVRA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
DLSDFDCRNNRLAQLGLVQDGFDARVAAAVSRHGAARVGVFIGTSTSGILETERAYEQRD
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
PASGALPAGFRYAHTHNPYSAAAFVRAYFSLRGPATAISSACSSGAKVFGSARRMIEAGL
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAAVVGGVDSLCLTTLYGFNSLELLSRKPCRPFDVARDGISIGEAAAFALLERVPETRA
HHHHHHCCHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHH
ALDGDAILLLGVGESSDAHHMSSPHPDGLGARVAIEQALASAGLDASDIDYVNLHGTATP
HCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
SNDAAESRAVGALLARTPCSSTKGATGHTLGAAGALEAVVAALALREQFVPAGVNTTQPD
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PALAADYVLASRDAHLRAVLSNSFGFGGTNCSLILGRAEHARRREPT
CHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]