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The map label for this gene is rmlA1 [C]

Identifier: 115352816

GI number: 115352816

Start: 3047428

End: 3048147

Strand: Direct

Name: rmlA1 [C]

Synonym: Bamb_2765

Alternate gene names: 115352816

Gene position: 3047428-3048147 (Clockwise)

Preceding gene: 115352815

Following gene: 115352818

Centisome position: 85.69

GC content: 71.39

Gene sequence:

>720_bases
ATGAGCACTACCCTCACCACGGCGATGATCTTCGCCGCCGGGCGCGGCGAGCGGATGCGTCCGCTGACCGACGCCCGCCC
GAAGCCGCTGCTCGAAGCCGGCGGCAAGCCGCTGATCGTCTGGCAGATCGAAGCACTCGCCCGCGCGGGCATCGAGACCA
TCGTGATCAACCACGCGTGGCTCGGCGAACAGTTCGAGGCGACGCTCGGCGACGGCTCGCGTTGGGGCGTGCGCCTCGCG
TATTCGGCCGAAGGCGACGCGCTGGAAACCGCCGGCGGCATCGCGCAGGCGCTGCCGCTGCTCGAGCGCGACGGCCGGCC
CACGGTGTTCGCGGGCGTCGCGGGCGACGTGTACTGCACATTCGACTACGGGACGCTCGCCGCCCCCGCCGCCCGAATGG
CCACGCTGGATGTGCCCACGATGCATCTCGTGATGGTGCCGAACCCGCCGTTCCATCCGGACGGCGATTTCGTGCTCCGC
GACGACGGCTTGCTCGCGCTCGCCGGCGCCCCGCGCGTCACGTTCGGCAGCATCGGCGTGTACGACACGCGGATGTTCCA
CGACATCGTGCCGGGCACGCACCGCGCGCTGTCGCCCTACTTCAGGGCGACCATCGAGGCCGGCCGCGCGACCGGCGAAT
TGTATGAAGGTATCTGGGAGAACGTCGGCACGCCCGCGCAGCTCGGCGAGCTCGACGCGCGGCTGCGCGCCGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGTTCGCGAAGCTGCTCGACGAGCTCGAGGGCAAGGGCGCGGCCGACGTCGGCTATACATTCTGACCGTTCTGACCGCT
CTCACATTCAGACGAACAAC

Downstream 100 bases:

>100_bases
TCGTTTCGCGGCCGCCGCCGGGCCATCCGGCGGTGACCGCGCAACGCCGGCCGATTCCGGACGGCCGCCAAACCATCCGC
CCGCGCCGCGCGCGGGCCGC

Product: nucleotidyl transferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Nucleotidyltransferase Family Protein; Nucleotidyl Transferase Family Protein; Sugar-Phosphate Nucleotidyl Transferase; Mannose-1-Phosphate Guanyltransferase; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; Mannose-1-Phosphate Guanylyltransferase; Nucleotidyltransferase; Nucleotidyl Transferase Superfamily; Mannose-1-Phosphate Guanyltransferase-Related Protein; Nucleotidyl Transferase Protein; Nucleotidyltransferase Protein; Transaldolase AB; ADP-Glucose Pyrophosphorylase; Mannose-1-Phosphate Guanyltransferase Protein; SMC Domain-Containing Protein; D-Alpha-D-Mannose-1-Phosphate Guanylyltransferase ManB; Nucleotidyl Transferase Family; Phosphoglucomutase; Nucleotidyl Transferase Superfamily Protein; Sugar Phosphate Nucleotidyltransferase; Nucleotidyl Transferase Domain Protein; Glucose-1-Phosphate Nucleotidyltransferase

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSTTLTTAMIFAAGRGERMRPLTDARPKPLLEAGGKPLIVWQIEALARAGIETIVINHAWLGEQFEATLGDGSRWGVRLA
YSAEGDALETAGGIAQALPLLERDGRPTVFAGVAGDVYCTFDYGTLAAPAARMATLDVPTMHLVMVPNPPFHPDGDFVLR
DDGLLALAGAPRVTFGSIGVYDTRMFHDIVPGTHRALSPYFRATIEAGRATGELYEGIWENVGTPAQLGELDARLRAAG

Sequences:

>Translated_239_residues
MSTTLTTAMIFAAGRGERMRPLTDARPKPLLEAGGKPLIVWQIEALARAGIETIVINHAWLGEQFEATLGDGSRWGVRLA
YSAEGDALETAGGIAQALPLLERDGRPTVFAGVAGDVYCTFDYGTLAAPAARMATLDVPTMHLVMVPNPPFHPDGDFVLR
DDGLLALAGAPRVTFGSIGVYDTRMFHDIVPGTHRALSPYFRATIEAGRATGELYEGIWENVGTPAQLGELDARLRAAG
>Mature_238_residues
STTLTTAMIFAAGRGERMRPLTDARPKPLLEAGGKPLIVWQIEALARAGIETIVINHAWLGEQFEATLGDGSRWGVRLAY
SAEGDALETAGGIAQALPLLERDGRPTVFAGVAGDVYCTFDYGTLAAPAARMATLDVPTMHLVMVPNPPFHPDGDFVLRD
DGLLALAGAPRVTFGSIGVYDTRMFHDIVPGTHRALSPYFRATIEAGRATGELYEGIWENVGTPAQLGELDARLRAAG

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI11761621, Length=122, Percent_Identity=34.4262295081967, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI11761619, Length=122, Percent_Identity=34.4262295081967, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=121, Percent_Identity=38.8429752066116, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=120, Percent_Identity=39.1666666666667, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21355443, Length=123, Percent_Identity=37.3983739837398, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24644084, Length=123, Percent_Identity=37.3983739837398, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 25501; Mature: 25370

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTLTTAMIFAAGRGERMRPLTDARPKPLLEAGGKPLIVWQIEALARAGIETIVINHAW
CCCHHEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEHHHHHCCCEEEEEECCC
LGEQFEATLGDGSRWGVRLAYSAEGDALETAGGIAQALPLLERDGRPTVFAGVAGDVYCT
CCCHHEEECCCCCCCCEEEEEECCCCCHHHHCHHHHHHHHHHCCCCCEEEEECCCCEEEE
FDYGTLAAPAARMATLDVPTMHLVMVPNPPFHPDGDFVLRDDGLLALAGAPRVTFGSIGV
ECCCCHHCCHHHEEEECCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEECCCCC
YDTRMFHDIVPGTHRALSPYFRATIEAGRATGELYEGIWENVGTPAQLGELDARLRAAG
CHHHHHHHHCCCCCHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTLTTAMIFAAGRGERMRPLTDARPKPLLEAGGKPLIVWQIEALARAGIETIVINHAW
CCHHEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEHHHHHCCCEEEEEECCC
LGEQFEATLGDGSRWGVRLAYSAEGDALETAGGIAQALPLLERDGRPTVFAGVAGDVYCT
CCCHHEEECCCCCCCCEEEEEECCCCCHHHHCHHHHHHHHHHCCCCCEEEEECCCCEEEE
FDYGTLAAPAARMATLDVPTMHLVMVPNPPFHPDGDFVLRDDGLLALAGAPRVTFGSIGV
ECCCCHHCCHHHEEEECCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCEEECCCCC
YDTRMFHDIVPGTHRALSPYFRATIEAGRATGELYEGIWENVGTPAQLGELDARLRAAG
CHHHHHHHHCCCCCHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA