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The map label for this gene is nadB1 [H]

Identifier: 115352602

GI number: 115352602

Start: 2806179

End: 2807765

Strand: Direct

Name: nadB1 [H]

Synonym: Bamb_2551

Alternate gene names: 115352602

Gene position: 2806179-2807765 (Clockwise)

Preceding gene: 115352601

Following gene: 115352609

Centisome position: 78.9

GC content: 67.93

Gene sequence:

>1587_bases
ATGAAATTCGACGTGGCGATCGTCGGCAGCGGCCTGGCAGGGCTGTCGGTCGCACTCAACCTGGCCAGCACGCGACGTGT
CGCGCTGATCGCGAAACGTTCGATGATGGAGGGGGCGAGCGATAACGCGCAAGGCGGCATCGCGGCCGTCCTCGACTCGG
CGGACAGCATCCAGAACCACGTCGACGACACGCTGGTCGCCGGCGGCGGGCTGTGCGACGAAGGCGCGACGCGCTACATC
GTCGAGCACGGCCGCGAAGCGATTGAATGGCTGATCTCGCAAGGCGTGCCGTTCACGAAGGACGATGCGGCCGAACTCGG
CTTCCATCTGACGCGCGAAGGCGGCCACAGCCACCGCCGGATCATCCACGCGGCCGACGCGACCGGCCACGCGGTGCTCG
CGACGCTGTCCGACCGCGCGCGCCAGCATCCGAACATCACGTTCTTCGAAAACCACCATGCGATCGACCTGATCACGTCG
GACCGGCTCGGCCTGCCCGGCCGCCGCTGTCACGGGCTGTATGCGCTCGACGTCGACAACGACCGCACGATCACGATCGA
GGCGCCGCACACGGTGCTTGCGACCGGCGGCGCCGGCAAGGTCTACCTGTACACCACGAACCCCGACACCGCGACCGGCG
ACGGCATCGCGATGGCGTGGCGCGCGGGCTGCCGCGTGTCGAACATGGAATTCATCCAGTTCCACCCGACCTGCCTGTTC
CATCCGTATGCGAAATCGTTCCTGATCTCGGAAGCCGTGCGCGGCGAAGGCGGCTTGCTGAAGCTGCCGGACGGCACGCG
CTTCATGCCCGCGCACGATCCGCGCGCGGAACTCGCGCCGCGCGACATCGTCGCGCGCGCGATCGACTTCGAGATCAAGA
AGCGCGGGATCGACTGCGTGTATCTCGACATCAGCCATCAGCCGGAAGCGTTCCTGCGCGAACACTTCCCGACGATCCAC
GCGCGCTGCCTCGAATTCGGCATCGACATTGCCCGGCAGCCCATTCCGGTCGTGCCGGCCGCGCACTACACGTGCGGCGG
TGTCGTCACCGACCTCGCGGGGCGCACCGATCTCGCGGGCCTGTATGCGGTCGGCGAAACGTCGTACACGGGGCTGCACG
GCGCGAACCGGCTCGCGAGCAACTCGCTGCTCGAATGCCTCGTGATCGGCCGCGCGGCGGCGGAGGCGATCGAGGCGGCC
GGCTTCGACGCCCAAACGCCGGCCACGCTGCCCGCATGGGACGAAAGCCGCGTGTCGGATGCGGATGAGGAAGTCGTCGT
GGCGCACAACTGGGACGAGCTGCGCCGGCTGATGTGGAACTACGTCGGCATCGTGCGTACCGACAAGCGTCTGGAACGCG
CGAAGCACCGCTTGTCGCTGCTGCGCGACGAGATCCACGAGTACTACGCGAATTTCCGCGTGACGCGCGACCTGCTCGAA
CTGCGCAATCTGGTCGACGTCGCGACGCTGATCGTGAAGAGCGCCTACTCGCGCCGCGAAAGCCGCGGCCTGCACTACAG
CCGCGACTGGCCGCACACGCTGCCGAAGGCGCTGCCGAGCGTGCTCACGCCGCGCTCGCGCCGCTGA

Upstream 100 bases:

>100_bases
TTGCGCATACGCGCGCGGGCCCGACGCGGTATGCTCTCCCCTTTCCGCGGCCACAGCCGACGGAACGCACAAGTCTAAAG
CGTAACGATGGAGATGCAGC

Downstream 100 bases:

>100_bases
CCGGCACGCCCTTCCCGGGGCGGCCACCATACAGAAAAAGGCCGTTGGCGCTTGCACGCCAACGGCCTTTTTCGTCAGAC
GACATCCCGCGAGGTCAGTC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIQNHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSDRARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIARQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDAQTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAYSRRESRGLHYSRDWPHTLPKALPSVLTPRSRR

Sequences:

>Translated_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIQNHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSDRARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIARQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDAQTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAYSRRESRGLHYSRDWPHTLPKALPSVLTPRSRR
>Mature_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIQNHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSDRARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPTIH
ARCLEFGIDIARQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDAQTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAYSRRESRGLHYSRDWPHTLPKALPSVLTPRSRR

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=506, Percent_Identity=34.1897233201581, Blast_Score=239, Evalue=5e-63,
Organism=Escherichia coli, GI1788928, Length=524, Percent_Identity=59.7328244274809, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1790597, Length=524, Percent_Identity=36.0687022900763, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1786942, Length=551, Percent_Identity=33.2123411978221, Blast_Score=217, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17550100, Length=528, Percent_Identity=33.5227272727273, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17505833, Length=529, Percent_Identity=32.5141776937618, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71986328, Length=467, Percent_Identity=27.6231263383298, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322701, Length=526, Percent_Identity=32.6996197718631, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6322416, Length=514, Percent_Identity=33.0739299610895, Blast_Score=223, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6322511, Length=474, Percent_Identity=27.6371308016878, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6320788, Length=482, Percent_Identity=28.2157676348548, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137288, Length=533, Percent_Identity=33.3958724202627, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24655642, Length=533, Percent_Identity=33.3958724202627, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24655647, Length=533, Percent_Identity=33.3958724202627, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24663005, Length=550, Percent_Identity=32.3636363636364, Blast_Score=224, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57968; Mature: 57968

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIQNH
CEEEEEEECCCCCHHHHHEEHHCCHHHHHHHHHHHHCCCCCCCCCCHHEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSDRARQHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVDN
EEEECCCCCCEEEEEHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCHHCEEEEEECCC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPTIHARCLEFGIDIARQPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAAGFDAQTPATLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAYSRRESRGLHYSRDWPHTLPKALPSVLTPRSRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIQNH
CEEEEEEECCCCCHHHHHEEHHCCHHHHHHHHHHHHCCCCCCCCCCHHEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSDRARQHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVDN
EEEECCCCCCEEEEEHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCHHCEEEEEECCC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPAHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPTIHARCLEFGIDIARQPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAAGFDAQTPATLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAYSRRESRGLHYSRDWPHTLPKALPSVLTPRSRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]