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The map label for this gene is cobC [H]

Identifier: 115352548

GI number: 115352548

Start: 2755887

End: 2756906

Strand: Direct

Name: cobC [H]

Synonym: Bamb_2497

Alternate gene names: 115352548

Gene position: 2755887-2756906 (Clockwise)

Preceding gene: 115352547

Following gene: 115352549

Centisome position: 77.49

GC content: 72.16

Gene sequence:

>1020_bases
ATGTCTGACGCACGCATCCCGCACGGCGGCAACCTGCACGAAGCCGCGCGCCGCCACGGCATTCCGCACGACGACTGGCT
CGACCTGTCGACCGGCATCAATCCGATCGGGTATCCGGTGCCGCCGGTCCCGGCCGACGCCTGGCGCCGGCTGCCCGACG
ACGGCGATGCGCTCGCCGCGTGCGCGGCCGGCTACTATCACGCACCCGATGCCGCGCACGTGCTGCCGGTCGCCGGCAGC
CAGGCCGCGATCCGCGCGTTGCCCGCGCTGCTGCCAATCGGCGACGCCGGCGTCGCGGCGCTCGCGTATGGCGAATACGC
GCCGGCCTTCGCCCGCCACGGCCATCGCGTCGTGCCGCTCGACATCGACGCGAACGTGTTGCCTGCAACGGTGCGTCACG
TCATCGTCGGGAATCCGAATAATCCGACCGCCGAATGCGTGCCGGTCGAGCGGCTGCTCGGCTGGCATGCGCAGCTGTCG
GCACGCGGCGGCACGCTGATCGTCGACGAGGCCTTCGCGGATACGGGCGCTACGCCCTCGCTCGCGCAGTACACCGATCG
CCAGGGTCTCGTCGTGCTGCGCTCGGTCGGCAAGTTCTTCGGGCTCGCCGGCATTCGCGCGGGCTTCGTGCTCGCGCATC
CCGACCTGATCGCCGCGCTGCGCGACGTGCTCGGCGCATGGACCGTCAGCGGCCCTGCGCGTCATGCAGTGACCGCCGCG
TTCGCCGATCGCGCATGGCAGGCGGCCGCGCGCGAACGGCTCGCGACCGACGGCGAACGACTCGCCACGCTGTTGCGCAT
GCACGGCTTCGCGGTGCACGCGACACCGCTCTTCAGCTGGACCGACGACCCGCGCGCCAGCCCGTTGCATGCGGCGCTCG
CCGCGCGCGGAATCTGGACGCGGTACTTCGCGCAACCGTCGAGCGTGCGCGTCGGCCTGCCGGGCTGCGAAGCCGAATGG
CGGCGGCTCGCCGGTGCGCTCGCGGAGTGCGTCCCGATGCTGCAACAGGTATCCGCATGA

Upstream 100 bases:

>100_bases
GCCGTGCACGTGGTCGCCGCGCTGTCGCTCGTCACGCGCACGCTCGCGCTGTGGCTCGCGCTGCTCGTCGCGAGCGGCGC
ACTCATCCTCGCTACCCATC

Downstream 100 bases:

>100_bases
ACGCTCGCTTGTCGCGCCTGTTGCGACCGCTGCCGCCGCTCGCGATGCTGGTCGCGCTCGCGCTCGCGCACGCGCCCGTC
GCTCACGCCGACGTCACGGC

Product: putative threonine-phosphate decarboxylase

Products: NA

Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSDARIPHGGNLHEAARRHGIPHDDWLDLSTGINPIGYPVPPVPADAWRRLPDDGDALAACAAGYYHAPDAAHVLPVAGS
QAAIRALPALLPIGDAGVAALAYGEYAPAFARHGHRVVPLDIDANVLPATVRHVIVGNPNNPTAECVPVERLLGWHAQLS
ARGGTLIVDEAFADTGATPSLAQYTDRQGLVVLRSVGKFFGLAGIRAGFVLAHPDLIAALRDVLGAWTVSGPARHAVTAA
FADRAWQAAARERLATDGERLATLLRMHGFAVHATPLFSWTDDPRASPLHAALAARGIWTRYFAQPSSVRVGLPGCEAEW
RRLAGALAECVPMLQQVSA

Sequences:

>Translated_339_residues
MSDARIPHGGNLHEAARRHGIPHDDWLDLSTGINPIGYPVPPVPADAWRRLPDDGDALAACAAGYYHAPDAAHVLPVAGS
QAAIRALPALLPIGDAGVAALAYGEYAPAFARHGHRVVPLDIDANVLPATVRHVIVGNPNNPTAECVPVERLLGWHAQLS
ARGGTLIVDEAFADTGATPSLAQYTDRQGLVVLRSVGKFFGLAGIRAGFVLAHPDLIAALRDVLGAWTVSGPARHAVTAA
FADRAWQAAARERLATDGERLATLLRMHGFAVHATPLFSWTDDPRASPLHAALAARGIWTRYFAQPSSVRVGLPGCEAEW
RRLAGALAECVPMLQQVSA
>Mature_338_residues
SDARIPHGGNLHEAARRHGIPHDDWLDLSTGINPIGYPVPPVPADAWRRLPDDGDALAACAAGYYHAPDAAHVLPVAGSQ
AAIRALPALLPIGDAGVAALAYGEYAPAFARHGHRVVPLDIDANVLPATVRHVIVGNPNNPTAECVPVERLLGWHAQLSA
RGGTLIVDEAFADTGATPSLAQYTDRQGLVVLRSVGKFFGLAGIRAGFVLAHPDLIAALRDVLGAWTVSGPARHAVTAAF
ADRAWQAAARERLATDGERLATLLRMHGFAVHATPLFSWTDDPRASPLHAALAARGIWTRYFAQPSSVRVGLPGCEAEWR
RLAGALAECVPMLQQVSA

Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005860
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.1.1.81 [H]

Molecular weight: Translated: 35840; Mature: 35709

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDARIPHGGNLHEAARRHGIPHDDWLDLSTGINPIGYPVPPVPADAWRRLPDDGDALAA
CCCCCCCCCCCHHHHHHHCCCCCCCCEEHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHH
CAAGYYHAPDAAHVLPVAGSQAAIRALPALLPIGDAGVAALAYGEYAPAFARHGHRVVPL
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHCCCEEEEE
DIDANVLPATVRHVIVGNPNNPTAECVPVERLLGWHAQLSARGGTLIVDEAFADTGATPS
ECCCCHHHHHEEEEEECCCCCCCCCEEEHHHHHCHHHHEECCCCEEEEECCCCCCCCCCH
LAQYTDRQGLVVLRSVGKFFGLAGIRAGFVLAHPDLIAALRDVLGAWTVSGPARHAVTAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
FADRAWQAAARERLATDGERLATLLRMHGFAVHATPLFSWTDDPRASPLHAALAARGIWT
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
RYFAQPSSVRVGLPGCEAEWRRLAGALAECVPMLQQVSA
HHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDARIPHGGNLHEAARRHGIPHDDWLDLSTGINPIGYPVPPVPADAWRRLPDDGDALAA
CCCCCCCCCCHHHHHHHCCCCCCCCEEHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHH
CAAGYYHAPDAAHVLPVAGSQAAIRALPALLPIGDAGVAALAYGEYAPAFARHGHRVVPL
HHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHCCCEEEEE
DIDANVLPATVRHVIVGNPNNPTAECVPVERLLGWHAQLSARGGTLIVDEAFADTGATPS
ECCCCHHHHHEEEEEECCCCCCCCCEEEHHHHHCHHHHEECCCCEEEEECCCCCCCCCCH
LAQYTDRQGLVVLRSVGKFFGLAGIRAGFVLAHPDLIAALRDVLGAWTVSGPARHAVTAA
HHHHCCCCCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHH
FADRAWQAAARERLATDGERLATLLRMHGFAVHATPLFSWTDDPRASPLHAALAARGIWT
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
RYFAQPSSVRVGLPGCEAEWRRLAGALAECVPMLQQVSA
HHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]