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The map label for this gene is lysN [H]

Identifier: 115352438

GI number: 115352438

Start: 2632458

End: 2633639

Strand: Direct

Name: lysN [H]

Synonym: Bamb_2387

Alternate gene names: 115352438

Gene position: 2632458-2633639 (Clockwise)

Preceding gene: 115352437

Following gene: 115352439

Centisome position: 74.02

GC content: 68.53

Gene sequence:

>1182_bases
ATGAATCCGACCGACCTGCATCCGCCGCATTGGCAGCTTTCCGAACGCGCCCGCAAGCTGACGAGCTCTGCGATCCGCGA
GATCCTGAAGGTCACGGAACGCCCCGAGGTCATCTCGTTCGCAGGCGGCCTGCCGGCTCCGGCGACGTTCCCGGCCGAAC
GCATGCGCGCCGCGGCCGACCGCGTGCTGCGCGACGCGCCCGCCGCCGCACTCCAGTACAGCGCGACCGAAGGCTACCTG
CCGCTGCGCGAATGGATCGCCGAGCGCTACAGCGTGCGCGTGTCGCAGGTGCTGATCACGACCGGCTCGCAGCAGGCACT
CGACCTGCTCGGCAAGGCGCTGATCGATCCGAACAGCCCGATCCTCGTCGAAACCCCGACTTACCTCGGCGCGCTGCAAT
CGTTCTCGCTGTACGAGCCGCGCTACGTGCAGGTGCCGACCGACGAGCAGGGCCTGTTGCCCGAAGGCCTCACGCCCGAG
CTGACCCAAGGCGCGCGCCTGCTGTACGCGCAGCCGAACTTCCAGAACCCGACCGGCCGCCGCCTGCCCGTCGAGCGCCG
CCGCGCGCTCGCCGCGTTCGCGCAGTCGAGCCCGTTCCCGGTGCTGGAAGACGACCCGTACGGCGCGCTGAACTACCAGG
GCGAGCCGCTGCCGACGATGCTGTCGATGGCGCCCGACCACATCGTGCACCTCGGCACGTTCTCGAAGGTGCTCGCGCCG
GGCCTGCGGATCGGCTACATCATTGCCCCCGAAGAACTCCACTTCAAGCTCGTGCAGGCCAAGCAGGCCACCGACCTGCA
CACGCCGACGCTCACGCAGCGCATCGCGCACGAAGTGATCAAGGACGGCTTCCTCGACGAGCACATCCCGACGATCCGCC
AGTTGTACGGCGCGCAGTGCGAAGCGATGCTCGCGTCGCTCGCGCGGCACATGCCGGAAGGCGTCACGTGGAACCGTCCG
GAAGGCGGGATGTTCATCTGGGTGAACCTGCCCGCGCAGATCGACAGCATGAAGCTGCTCGCCACGGCCGTGGACAACCA
CGTCGCCTTCGTGCCGGGCGCGCCGTTCTTCGCGGACGATGCTCAACAGAACACGCTGCGCCTGTCGTTCGTGACGGTGC
CGCCCGAGAAGATCGAGGAAGGCGTGGCGCGGCTCGGCAAGCTGCTGCGCGAGCGCCTCTAA

Upstream 100 bases:

>100_bases
GCGACGGCCCGATCGCGCTCCCGCAAGCCTACCCGGCCGCGTCGACGCAATCTGCCTGATCGACCTTTCTTGACTGACCC
GATATCCGAACGAGGAGACT

Downstream 100 bases:

>100_bases
TCCCCCGCTTTTTCCTGTCACGACTCTCTACGAGGAATCGAACGCATGGCTAACGTCTACGACAAACTGAAGTCGCTCGG
CATCGAGCTCCCGACCGCCG

Product: class I/II aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNPTDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLASLARHMPEGVTWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADDAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Sequences:

>Translated_393_residues
MNPTDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLASLARHMPEGVTWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADDAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
>Mature_393_residues
MNPTDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSPILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPE
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQSSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLASLARHMPEGVTWNRP
EGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADDAQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=410, Percent_Identity=29.5121951219512, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI33469970, Length=410, Percent_Identity=29.5121951219512, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=27.8215223097113, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1790797, Length=336, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI48994949, Length=227, Percent_Identity=27.3127753303965, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=485, Percent_Identity=23.7113402061856, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=264, Percent_Identity=27.6515151515151, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=341, Percent_Identity=23.4604105571848, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21356535, Length=395, Percent_Identity=27.5949367088608, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43521; Mature: 43521

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQSSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAMLASLARHMPEGVTWNRPEGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADD
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPTDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYSVRVSQVLITTGSQQALDLLGKALIDPNSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQVPTDEQGLLPEGLTPELTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQSSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAMLASLARHMPEGVTWNRPEGGMFIWVNLPAQIDSMKLLATAVDNHVAFVPGAPFFADD
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA