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The map label for this gene is degU [H]

Identifier: 115352308

GI number: 115352308

Start: 2495076

End: 2495906

Strand: Direct

Name: degU [H]

Synonym: Bamb_2257

Alternate gene names: 115352308

Gene position: 2495076-2495906 (Clockwise)

Preceding gene: 115352307

Following gene: 115352309

Centisome position: 70.15

GC content: 67.15

Gene sequence:

>831_bases
ATGCGGTTCCTGGTGTTGAACTCAGACGCCGAACGGCGTGACGGACTGAAGGCCCTGCTGCGGCAGATCGACCGTCACGC
CAGCATCAACGATGCGCCCGACGGTTTCCAGGCGCGTCGATTGCTGCGCGCCCAGCGTTTCGACCTCGTCGCAATCAACT
GGCCGGACGTCGGCCGGCTCAGCGAACTGCAGGCACTCTGCAGCGCCTGCTCGCCGACGCCCGCCGCGGTATTGATCGAC
GAATCCACGCCGGAAGCCATCCAGCGCTTTTACAACTATGGCGTCGCGGGCGTGATCCCGCACTCCATGCGGCCGCACCT
GATCGTGCGGGCTCTCGAAATGGTGCTGCTGGGCGGCCACTACATTCCGCCCATTGCGCTGAGCCTGCTGCCCTCCGCCG
CCGCGGCCCGCCACGACGCCCATTTCCAGACGCTCGCCGGATCGCTGCCGCGCCGCCCGGCAAGCCGCCTCCTGTCGCCG
AGACAGGCGCAAATCATGCGCTTCGTCCACATGGGCAACACCAACAAGATGATCGCCCGCACGCTAGGCATCAGCGAAGG
CACCGTAAAGATCCACCTCGCCAGCATCTTCCAGCAGCTTGGCGCGGCAAACCGGGCCGCGGCCGTCGCGATCTACAACG
GCTGGCTGTCGCCGCATCTCGAGGTGCTGCTGGCAAACCGTGAGCGTGCAGACAAGCCGACCATCGGCGAACGCGGCCCG
GTTCCGCTGCGCAGGCAACGGAAGAACCGTCCGTATCCGCTGCCGGACGCAAACACCGCGGACCTGCCGCTCGCGGCCGA
ACCGCCGGCACGGTTTCGGCGCGAACGCTAG

Upstream 100 bases:

>100_bases
CTTTCAGCCAAGCAGACATCGTGTAAGGTCTTTGTCATGATCGGATCCACGCCAAGACATGCCGACGGCAAATCAATGAC
TCACCTTACGGAGGTTGAAT

Downstream 100 bases:

>100_bases
TCGGACAGTATCGATATTGCGACGGTCAGCAAGTGCGGATTCCCACCTTTGATGCTCAACGAGTAATATGGACGCATGGG
TTTTCTTTTCACACCGCTTC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRLSELQALCSACSPTPAAVLID
ESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGHYIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSP
RQAQIMRFVHMGNTNKMIARTLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERADKPTIGERGP
VPLRRQRKNRPYPLPDANTADLPLAAEPPARFRRER

Sequences:

>Translated_276_residues
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRLSELQALCSACSPTPAAVLID
ESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGHYIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSP
RQAQIMRFVHMGNTNKMIARTLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERADKPTIGERGP
VPLRRQRKNRPYPLPDANTADLPLAAEPPARFRRER
>Mature_276_residues
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRLSELQALCSACSPTPAAVLID
ESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGHYIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSP
RQAQIMRFVHMGNTNKMIARTLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERADKPTIGERGP
VPLRRQRKNRPYPLPDANTADLPLAAEPPARFRRER

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30569; Mature: 30569

Theoretical pI: Translated: 11.39; Mature: 11.39

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRL
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCHH
SELQALCSACSPTPAAVLIDESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGH
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSPRQAQIMRFVHMGNTNKMIAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCHHHHH
TLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERADKPTIGERGP
HHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
VPLRRQRKNRPYPLPDANTADLPLAAEPPARFRRER
CCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRL
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCHH
SELQALCSACSPTPAAVLIDESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGH
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSPRQAQIMRFVHMGNTNKMIAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCHHHHH
TLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERADKPTIGERGP
HHCCCCCEEEEHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
VPLRRQRKNRPYPLPDANTADLPLAAEPPARFRRER
CCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]