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The map label for this gene is pgl [H]

Identifier: 115352272

GI number: 115352272

Start: 2448379

End: 2449428

Strand: Direct

Name: pgl [H]

Synonym: Bamb_2221

Alternate gene names: 115352272

Gene position: 2448379-2449428 (Clockwise)

Preceding gene: 115352271

Following gene: 115352274

Centisome position: 68.84

GC content: 72.95

Gene sequence:

>1050_bases
ATGCCGAACACTGATCGCCTGACCGTCGTCGTCTCGAATGCCGTCGACGGCGACCTCGCCACGTTCTCGCTCACGTCCGA
CGGCGCGCTCGCGCCGCTCGCCCGCTACCCGGCCGGCGACGCCGCGATGCCCGTCGCCGTGCAGCCCGATCGCGCGCGGC
TGTACGTCGCGACGCGCGGCGAGCAGCCGACGATCGTCGCGTTCCGCGTCGCGACCGGCACCGGCGCGTTCGCCCGCATC
GGCGCGACCGCGATCGACGCGAGCCTTGCGTACCTGTCGCTCGACCGCAGCGGCCGCTGGCTGCTCGGCGCGTCGTACGG
CGGCAATTCGCTGAGCCTCTACGACGCCGCACACGTACGTGACGGCGACGGCGCGCCGCTGCAGGTCGTACACGGCATCG
CGAACGCGCATGCCGTCGTCGTGTCGCCGGACAACCGCTTCGCGTATGTGAGTTCGCTCGGCTCGGACCGGATCTTCACG
TTCGCGCTGGTCGAGGATGCCGGCGGCCTGCGTGCGCTCGAACACGGCGAAACGCGCGTGCCGGGCGGCTTCGGGCCGCG
TCACCTGCGCTTCGCGCGCGACGGCCGCGCGCTCGTCGCGGTCAGCGAATTCCAGGCCACGCTCGCGACCTTCGCACGCG
ACACCGACAGCGGCCGCCTCGGCGACGCGCAGGTCAGCGGGCGGCACGCGGCCGTCGCCGACCTCCCGCAAGGCCACGCG
CGCCCGCCCGCGCCGACCGTGCCCGCCGTGTGGGCCGCCGATCTGCACCTCACGCCCGACGAGCGCTTCGCGTATGTCAG
CGAACGCACGTCGAGCCAGTTGCTCTGCTATCGGCGCGCTGCGGACGGCAGCTTCGAACCGGTGCACGCGACGCTCACCG
AAACGCAGCCACGCGGCTTCGCGATCGACCCGTCGGGACGCTGGCTCGTCGCGTGCGGCGAACAGTCGGAATACGCGTCG
GTCTACGCGATCGCGCCGGACGACGGCACGCTGGCGTTGCATGCGCGCGTGCCGGGTGGGCGCGGCGCGAACTGGGTTGC
GATCGTCTGA

Upstream 100 bases:

>100_bases
GCGGCGGTCGCCGCGCTGTTCGCGCGCACGCACCGGCGCAGCGATCCGCCGCGCGGCCTGCCGGCCGACGAGTCCTTCAC
GAACACCGCGATGCTCCGCC

Downstream 100 bases:

>100_bases
TTCTGATTGTCGAATGACCGATGGATCGACGCCGTGCGCATGGCCGGCATCGGCCGACAGCGGCCCGCGCGCCGTCAGCG
CCGCTCGCTCGGCGCGACGC

Product: 3-carboxymuconate cyclase-like protein

Products: NA

Alternate protein names: 6-P-gluconolactonase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPNTDRLTVVVSNAVDGDLATFSLTSDGALAPLARYPAGDAAMPVAVQPDRARLYVATRGEQPTIVAFRVATGTGAFARI
GATAIDASLAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGAPLQVVHGIANAHAVVVSPDNRFAYVSSLGSDRIFT
FALVEDAGGLRALEHGETRVPGGFGPRHLRFARDGRALVAVSEFQATLATFARDTDSGRLGDAQVSGRHAAVADLPQGHA
RPPAPTVPAVWAADLHLTPDERFAYVSERTSSQLLCYRRAADGSFEPVHATLTETQPRGFAIDPSGRWLVACGEQSEYAS
VYAIAPDDGTLALHARVPGGRGANWVAIV

Sequences:

>Translated_349_residues
MPNTDRLTVVVSNAVDGDLATFSLTSDGALAPLARYPAGDAAMPVAVQPDRARLYVATRGEQPTIVAFRVATGTGAFARI
GATAIDASLAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGAPLQVVHGIANAHAVVVSPDNRFAYVSSLGSDRIFT
FALVEDAGGLRALEHGETRVPGGFGPRHLRFARDGRALVAVSEFQATLATFARDTDSGRLGDAQVSGRHAAVADLPQGHA
RPPAPTVPAVWAADLHLTPDERFAYVSERTSSQLLCYRRAADGSFEPVHATLTETQPRGFAIDPSGRWLVACGEQSEYAS
VYAIAPDDGTLALHARVPGGRGANWVAIV
>Mature_348_residues
PNTDRLTVVVSNAVDGDLATFSLTSDGALAPLARYPAGDAAMPVAVQPDRARLYVATRGEQPTIVAFRVATGTGAFARIG
ATAIDASLAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGAPLQVVHGIANAHAVVVSPDNRFAYVSSLGSDRIFTF
ALVEDAGGLRALEHGETRVPGGFGPRHLRFARDGRALVAVSEFQATLATFARDTDSGRLGDAQVSGRHAAVADLPQGHAR
PPAPTVPAVWAADLHLTPDERFAYVSERTSSQLLCYRRAADGSFEPVHATLTETQPRGFAIDPSGRWLVACGEQSEYASV
YAIAPDDGTLALHARVPGGRGANWVAIV

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate [H]

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786983, Length=352, Percent_Identity=30.6818181818182, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR011045
- InterPro:   IPR015943 [H]

Pfam domain/function: PF10282 DUF2394 [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 36683; Mature: 36552

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTDRLTVVVSNAVDGDLATFSLTSDGALAPLARYPAGDAAMPVAVQPDRARLYVATRG
CCCCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECC
EQPTIVAFRVATGTGAFARIGATAIDASLAYLSLDRSGRWLLGASYGGNSLSLYDAAHVR
CCCEEEEEEEECCCCCHHHHCCHHHCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGAPLQVVHGIANAHAVVVSPDNRFAYVSSLGSDRIFTFALVEDAGGLRALEHGETRV
CCCCCCCCEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCC
PGGFGPRHLRFARDGRALVAVSEFQATLATFARDTDSGRLGDAQVSGRHAAVADLPQGHA
CCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEECCCCCCC
RPPAPTVPAVWAADLHLTPDERFAYVSERTSSQLLCYRRAADGSFEPVHATLTETQPRGF
CCCCCCCCEEEEEEEEECCHHHEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCCCCCE
AIDPSGRWLVACGEQSEYASVYAIAPDDGTLALHARVPGGRGANWVAIV
EECCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEC
>Mature Secondary Structure 
PNTDRLTVVVSNAVDGDLATFSLTSDGALAPLARYPAGDAAMPVAVQPDRARLYVATRG
CCCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECC
EQPTIVAFRVATGTGAFARIGATAIDASLAYLSLDRSGRWLLGASYGGNSLSLYDAAHVR
CCCEEEEEEEECCCCCHHHHCCHHHCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGAPLQVVHGIANAHAVVVSPDNRFAYVSSLGSDRIFTFALVEDAGGLRALEHGETRV
CCCCCCCCEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCC
PGGFGPRHLRFARDGRALVAVSEFQATLATFARDTDSGRLGDAQVSGRHAAVADLPQGHA
CCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEECCCCCCC
RPPAPTVPAVWAADLHLTPDERFAYVSERTSSQLLCYRRAADGSFEPVHATLTETQPRGF
CCCCCCCCEEEEEEEEECCHHHEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCCCCCE
AIDPSGRWLVACGEQSEYASVYAIAPDDGTLALHARVPGGRGANWVAIV
EECCCCCEEEEECCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA