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The map label for this gene is puuP [H]

Identifier: 115351691

GI number: 115351691

Start: 1813303

End: 1814643

Strand: Direct

Name: puuP [H]

Synonym: Bamb_1639

Alternate gene names: 115351691

Gene position: 1813303-1814643 (Clockwise)

Preceding gene: 115351690

Following gene: 115351692

Centisome position: 50.98

GC content: 63.24

Gene sequence:

>1341_bases
ATGCAAGCGTCATCATCCAATGAACCCGCACGCCTGAAGCGGACACTCGGCCTGCCGTCCGTGCTGCTGTTCGGGCTCGC
CTACATGGCACCGCTGATCGTCTACGGTACTTACGGCGTGCTGGCCAAGGCCAGCGACGACACGGCCGCGCTGGCCTATC
TGCTCGCGCTTGTCGCCATCGCCTTCACCGCGCTCAGCTACGGCAAGCTCGCGCGGCTCCATCCGGCCGCGGGCTCGGCT
TATACGTACACGCGCAAGACGTTCAACCCGCATCTGGGTTTCATGATCGGCTGGGCAACGCTGCTCGATTACTTCTTTCT
GCCGATGGTGATCTGGCTGATCGGCGCGGCGTATCTGAACGCGGCATTTCCGCACGTGCCGACGTGGATCTGGATCGTGG
CGTTCATCGTGTTGACGAGCGGCCTGAACATCGTCGGCATCGATCTGGCCGCGCGGTTCAACATCGTGCTGATGGTCGTG
CAGCTGGCGGTCGTCGCGATGTTCGTCGTGCTGTGCGTGCACTATGCGTCGGCTGCGGCAGGCGCGGGCGGTATTGCCAT
GGCGCAGCCACTCTTCAAGCCGCACGTGCCGTTCGGCGCGACGATGGCAGGCGCCGCGATTGCCGCCTATTCGTACCTCG
GCTTCGACGCGGTCTCGACGCTGACCGAAGAGACGATCGATCCGAAAAAGAACATGCCGCGCGCGATCCTGCTGATCGCA
CTGATCGGTGGAGCGATCTTCGTGATCGCGGCGTACACGATGCAGCTCGCGCACCCGGGAGTCGAATTCAAGGATACGGA
TTCGGCCGCGTTCGAAGTGGCGAAGATGATCGGCGGCGATCTGTTCGTCCCGGTGTTCCTCGCGGGCCTGATCCTCGCTC
AGTTCGCGTCGGGCATCTCCGCGCAAGCGAGTGTCGGCCGGTTGCTCTATGCGATGGGCCGCGACGAAATCCTGCCGAAG
CGCATCTTCGGTTTCATCCATCCGCGTTTCAAGACGCCCGCGATCAACATCGTGCTGGCCGGCAGCGTCGGGTTGATCGC
GCTGAAGCTGGATGTCGCCACGTCCACGTCGTTCATCAACTTCGGCGCGTTTCTGGCCTTTACAGCCGTCAATCTGTGCG
TGATCCGCCTGTACCTCCGGGGGCAGTCAGGCGAACGCCGGATTGGCGTGATCGGCGGACTCGTGTTTCCCGCGATCGGC
GCGGTTTCCGATATCTGGCTGCTCGTGAGCCTCGAGAAGGCTGCGCTCGTGCTCGGCGTCGCGTGGTTCGTGCTCGGGCT
GGTGTATCTGTGCTGGATAACGCGCCTGTTCCGCCAGGCACCGCCGGAAGTTGCGATTTGA

Upstream 100 bases:

>100_bases
GGCAGGGCGCAATGCCCTGCACGTGCTCGCCCGTCCCATTGAAATGCCGGCCCGACGGCATACAGGCTTTCGTATCGGCC
GCCGAGGCCCAGGAGACAAC

Downstream 100 bases:

>100_bases
GCGGGTCGCGGAAGGATGGGCAGCGGGTATTCGAATTCGGCTGGGAACATCACAAACCTTCGGCGGTCGGTATCGGCGCG
GAATCAACAATCCGGCGTTC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MQASSSNEPARLKRTLGLPSVLLFGLAYMAPLIVYGTYGVLAKASDDTAALAYLLALVAIAFTALSYGKLARLHPAAGSA
YTYTRKTFNPHLGFMIGWATLLDYFFLPMVIWLIGAAYLNAAFPHVPTWIWIVAFIVLTSGLNIVGIDLAARFNIVLMVV
QLAVVAMFVVLCVHYASAAAGAGGIAMAQPLFKPHVPFGATMAGAAIAAYSYLGFDAVSTLTEETIDPKKNMPRAILLIA
LIGGAIFVIAAYTMQLAHPGVEFKDTDSAAFEVAKMIGGDLFVPVFLAGLILAQFASGISAQASVGRLLYAMGRDEILPK
RIFGFIHPRFKTPAINIVLAGSVGLIALKLDVATSTSFINFGAFLAFTAVNLCVIRLYLRGQSGERRIGVIGGLVFPAIG
AVSDIWLLVSLEKAALVLGVAWFVLGLVYLCWITRLFRQAPPEVAI

Sequences:

>Translated_446_residues
MQASSSNEPARLKRTLGLPSVLLFGLAYMAPLIVYGTYGVLAKASDDTAALAYLLALVAIAFTALSYGKLARLHPAAGSA
YTYTRKTFNPHLGFMIGWATLLDYFFLPMVIWLIGAAYLNAAFPHVPTWIWIVAFIVLTSGLNIVGIDLAARFNIVLMVV
QLAVVAMFVVLCVHYASAAAGAGGIAMAQPLFKPHVPFGATMAGAAIAAYSYLGFDAVSTLTEETIDPKKNMPRAILLIA
LIGGAIFVIAAYTMQLAHPGVEFKDTDSAAFEVAKMIGGDLFVPVFLAGLILAQFASGISAQASVGRLLYAMGRDEILPK
RIFGFIHPRFKTPAINIVLAGSVGLIALKLDVATSTSFINFGAFLAFTAVNLCVIRLYLRGQSGERRIGVIGGLVFPAIG
AVSDIWLLVSLEKAALVLGVAWFVLGLVYLCWITRLFRQAPPEVAI
>Mature_446_residues
MQASSSNEPARLKRTLGLPSVLLFGLAYMAPLIVYGTYGVLAKASDDTAALAYLLALVAIAFTALSYGKLARLHPAAGSA
YTYTRKTFNPHLGFMIGWATLLDYFFLPMVIWLIGAAYLNAAFPHVPTWIWIVAFIVLTSGLNIVGIDLAARFNIVLMVV
QLAVVAMFVVLCVHYASAAAGAGGIAMAQPLFKPHVPFGATMAGAAIAAYSYLGFDAVSTLTEETIDPKKNMPRAILLIA
LIGGAIFVIAAYTMQLAHPGVEFKDTDSAAFEVAKMIGGDLFVPVFLAGLILAQFASGISAQASVGRLLYAMGRDEILPK
RIFGFIHPRFKTPAINIVLAGSVGLIALKLDVATSTSFINFGAFLAFTAVNLCVIRLYLRGQSGERRIGVIGGLVFPAIG
AVSDIWLLVSLEKAALVLGVAWFVLGLVYLCWITRLFRQAPPEVAI

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=26.302729528536, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI181337167, Length=371, Percent_Identity=24.2587601078167, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI258614003, Length=434, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI258614005, Length=434, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081869, Length=434, Percent_Identity=43.0875576036866, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI87082023, Length=444, Percent_Identity=39.6396396396396, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI87081708, Length=414, Percent_Identity=24.8792270531401, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082250, Length=388, Percent_Identity=23.1958762886598, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788480, Length=298, Percent_Identity=24.1610738255034, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786789, Length=288, Percent_Identity=22.5694444444444, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=402, Percent_Identity=24.3781094527363, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=397, Percent_Identity=25.1889168765743, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=24.7524752475248, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667468, Length=396, Percent_Identity=26.5151515151515, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668806, Length=479, Percent_Identity=24.6346555323591, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21356285, Length=479, Percent_Identity=24.6346555323591, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24668802, Length=479, Percent_Identity=24.6346555323591, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI221512776, Length=421, Percent_Identity=26.603325415677, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666159, Length=421, Percent_Identity=26.603325415677, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=23.9024390243902, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=23.9024390243902, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47556; Mature: 47556

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASSSNEPARLKRTLGLPSVLLFGLAYMAPLIVYGTYGVLAKASDDTAALAYLLALVAI
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHEEECCCCHHHHHHHHHHHHH
AFTALSYGKLARLHPAAGSAYTYTRKTFNPHLGFMIGWATLLDYFFLPMVIWLIGAAYLN
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFPHVPTWIWIVAFIVLTSGLNIVGIDLAARFNIVLMVVQLAVVAMFVVLCVHYASAAA
HCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGGIAMAQPLFKPHVPFGATMAGAAIAAYSYLGFDAVSTLTEETIDPKKNMPRAILLIA
CCCCHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LIGGAIFVIAAYTMQLAHPGVEFKDTDSAAFEVAKMIGGDLFVPVFLAGLILAQFASGIS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
AQASVGRLLYAMGRDEILPKRIFGFIHPRFKTPAINIVLAGSVGLIALKLDVATSTSFIN
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHCCCCHHH
FGAFLAFTAVNLCVIRLYLRGQSGERRIGVIGGLVFPAIGAVSDIWLLVSLEKAALVLGV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWFVLGLVYLCWITRLFRQAPPEVAI
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQASSSNEPARLKRTLGLPSVLLFGLAYMAPLIVYGTYGVLAKASDDTAALAYLLALVAI
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHEEECCCCHHHHHHHHHHHHH
AFTALSYGKLARLHPAAGSAYTYTRKTFNPHLGFMIGWATLLDYFFLPMVIWLIGAAYLN
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFPHVPTWIWIVAFIVLTSGLNIVGIDLAARFNIVLMVVQLAVVAMFVVLCVHYASAAA
HCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGGIAMAQPLFKPHVPFGATMAGAAIAAYSYLGFDAVSTLTEETIDPKKNMPRAILLIA
CCCCHHHHCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LIGGAIFVIAAYTMQLAHPGVEFKDTDSAAFEVAKMIGGDLFVPVFLAGLILAQFASGIS
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
AQASVGRLLYAMGRDEILPKRIFGFIHPRFKTPAINIVLAGSVGLIALKLDVATSTSFIN
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEHHCCCCHHH
FGAFLAFTAVNLCVIRLYLRGQSGERRIGVIGGLVFPAIGAVSDIWLLVSLEKAALVLGV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWFVLGLVYLCWITRLFRQAPPEVAI
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]