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The map label for this gene is emrA [H]

Identifier: 115351687

GI number: 115351687

Start: 1807937

End: 1809298

Strand: Direct

Name: emrA [H]

Synonym: Bamb_1634

Alternate gene names: 115351687

Gene position: 1807937-1809298 (Clockwise)

Preceding gene: 115351686

Following gene: 115351688

Centisome position: 50.83

GC content: 69.31

Gene sequence:

>1362_bases
ATGAGCAGCGACAACACCCTGCAGACTCCTCCTCGGCCCGCGGCCGCCGATCCTGCCAGCGCGCGCCAGCATCCCGTCGG
CGATCACCCGGGCGGATCGCGCTCGCCGGCCGACACCGCTCCCCGCGCGCAACCGGGAGCGGGCGGAACGGTACCCGCGG
CACCGCCCGCGCGACGCAAGCATCTGGTGCGTGCGCTCGTCGCCGTGTTCGCGTTCGGTATTGCCGGGTGGGGCGCCTGG
TATGCGCTCGTCGGCCGATGGTACGAAACGACCGACAACGCATACGCGCAAGGCAACGTCGTCGAGCTGACGCCGCAGGT
GACGGGCACCGTCGTGTCGATCGACGCGGACGACGGCGACCTCGTGCATGCAGGCACGCCGCTCGTGCGCCTCGACCCGA
GCGACGCGCAGGTCACGCTCGCGGCCGCACAGGCCGATCTCGCGGCAACCGTGCGGAAGGTGCGCGGCCTGTACAGCAAC
GAGCGCGGGCTCGCGAACAGCATTGACGGCGCGCGCGCCGAACTCGCCGCGCGCCGCACCGCGCTCGACAAGGCGAAGGC
CGACTACCGGCGCCGCGAGGATCTCGGCCGCTCCGGCGCGATTTCGCACGAGGAGCTCGCTCATGCACGCGATACATTGA
CGTCCGCGCAAAGCGCGTATGCGGCCGCGCAAAGTGCGCTCGCCACGTTGAGCGAACAGCATCAGACGAGCAAGGCACTG
GTCGACGACACCGCCGTCGCCTCTCATCCCGACGTTCAGGCCGCGGCGTCACGCCTGCGTGCCGCCTACCTGGCGCGCAC
TCGCACCGATATCGTCGCCCCCGTTACCGGCTATGTCGCGAAGCGCACGGTACAGGTCGGCCAGCGCGTGTCGCCGGGTG
TGCCGCTGCTCGCGGTCGTGCCGTTGCGCGAGTTGTGGGTCGATGCCAACTTCACCGAGAAGCAGCTCGACCACATGCGG
ATCGGCCAGCCTGTGGAACTGACGGCCGACCTGTACGGCAGCAATGTACGTTACAGCGGCCGCGTGCAGAGCCTCGGGGT
CGGCACCGGCAGCGCATTCTCGCTGCTGCCCGCCCAGAATGCGACCGGCAACTGGATCAAGATCGTGCAGCGGCTACCGG
TTCGTATCGAATTGACGGACCCGGCACAGCTCGACGCGCATCCGCTGCGCATCGGCCTGTCGATGCACGCAAGAGTCGAT
CAGCACGATCGCAGCGGCACAATGCTGTCGCAACGCGTGCAGCGAGATCCCGTGTTCCGCACCGACGTGTACCGTGAGGA
GCTCGCGCGCGCCGACGGGCTGATCGCCGATGTCCTGCATGCAAACCTGCCCGCGACGGCGCGCGCGGAGCGTGTGCGAT
GA

Upstream 100 bases:

>100_bases
ATCGCTGCAGCTCGTCGCGGCACTGGGCGGCGGCTTCCGCGCCGAACCCGACGACGTCGCGCTCGCCGCCACGCCTTCCC
ACCGTCCCTGAGATCGAACC

Downstream 100 bases:

>100_bases
GCGGGCCGATGCCGGCCGCCGATGGCGGCTTTCGCCCACCGAGCGTCGCGCTGACGACGTTCGGTCTCGCGCTCGCTGTC
TTCATGCAGGTGCTCGACGG

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSSDNTLQTPPRPAAADPASARQHPVGDHPGGSRSPADTAPRAQPGAGGTVPAAPPARRKHLVRALVAVFAFGIAGWGAW
YALVGRWYETTDNAYAQGNVVELTPQVTGTVVSIDADDGDLVHAGTPLVRLDPSDAQVTLAAAQADLAATVRKVRGLYSN
ERGLANSIDGARAELAARRTALDKAKADYRRREDLGRSGAISHEELAHARDTLTSAQSAYAAAQSALATLSEQHQTSKAL
VDDTAVASHPDVQAAASRLRAAYLARTRTDIVAPVTGYVAKRTVQVGQRVSPGVPLLAVVPLRELWVDANFTEKQLDHMR
IGQPVELTADLYGSNVRYSGRVQSLGVGTGSAFSLLPAQNATGNWIKIVQRLPVRIELTDPAQLDAHPLRIGLSMHARVD
QHDRSGTMLSQRVQRDPVFRTDVYREELARADGLIADVLHANLPATARAERVR

Sequences:

>Translated_453_residues
MSSDNTLQTPPRPAAADPASARQHPVGDHPGGSRSPADTAPRAQPGAGGTVPAAPPARRKHLVRALVAVFAFGIAGWGAW
YALVGRWYETTDNAYAQGNVVELTPQVTGTVVSIDADDGDLVHAGTPLVRLDPSDAQVTLAAAQADLAATVRKVRGLYSN
ERGLANSIDGARAELAARRTALDKAKADYRRREDLGRSGAISHEELAHARDTLTSAQSAYAAAQSALATLSEQHQTSKAL
VDDTAVASHPDVQAAASRLRAAYLARTRTDIVAPVTGYVAKRTVQVGQRVSPGVPLLAVVPLRELWVDANFTEKQLDHMR
IGQPVELTADLYGSNVRYSGRVQSLGVGTGSAFSLLPAQNATGNWIKIVQRLPVRIELTDPAQLDAHPLRIGLSMHARVD
QHDRSGTMLSQRVQRDPVFRTDVYREELARADGLIADVLHANLPATARAERVR
>Mature_452_residues
SSDNTLQTPPRPAAADPASARQHPVGDHPGGSRSPADTAPRAQPGAGGTVPAAPPARRKHLVRALVAVFAFGIAGWGAWY
ALVGRWYETTDNAYAQGNVVELTPQVTGTVVSIDADDGDLVHAGTPLVRLDPSDAQVTLAAAQADLAATVRKVRGLYSNE
RGLANSIDGARAELAARRTALDKAKADYRRREDLGRSGAISHEELAHARDTLTSAQSAYAAAQSALATLSEQHQTSKALV
DDTAVASHPDVQAAASRLRAAYLARTRTDIVAPVTGYVAKRTVQVGQRVSPGVPLLAVVPLRELWVDANFTEKQLDHMRI
GQPVELTADLYGSNVRYSGRVQSLGVGTGSAFSLLPAQNATGNWIKIVQRLPVRIELTDPAQLDAHPLRIGLSMHARVDQ
HDRSGTMLSQRVQRDPVFRTDVYREELARADGLIADVLHANLPATARAERVR

Specific function: The emr locus confers resistance to substances of high hydrophobicity. EmrA probably participate in a transport system to extrude toxins and drugs from the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789041, Length=391, Percent_Identity=44.7570332480818, Blast_Score=325, Evalue=5e-90,
Organism=Escherichia coli, GI1788711, Length=348, Percent_Identity=45.4022988505747, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1790519, Length=320, Percent_Identity=29.0625, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081951, Length=325, Percent_Identity=28.3076923076923, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48391; Mature: 48260

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDNTLQTPPRPAAADPASARQHPVGDHPGGSRSPADTAPRAQPGAGGTVPAAPPARRK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
HLVRALVAVFAFGIAGWGAWYALVGRWYETTDNAYAQGNVVELTPQVTGTVVSIDADDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCC
LVHAGTPLVRLDPSDAQVTLAAAQADLAATVRKVRGLYSNERGLANSIDGARAELAARRT
EEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ALDKAKADYRRREDLGRSGAISHEELAHARDTLTSAQSAYAAAQSALATLSEQHQTSKAL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDDTAVASHPDVQAAASRLRAAYLARTRTDIVAPVTGYVAKRTVQVGQRVSPGVPLLAVV
HCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PLRELWVDANFTEKQLDHMRIGQPVELTADLYGSNVRYSGRVQSLGVGTGSAFSLLPAQN
CHHHHHCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCEECCCEEEEECCCCCCEEEECCCC
ATGNWIKIVQRLPVRIELTDPAQLDAHPLRIGLSMHARVDQHDRSGTMLSQRVQRDPVFR
CCCHHHHHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHH
TDVYREELARADGLIADVLHANLPATARAERVR
HHHHHHHHHHHCCHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure 
SSDNTLQTPPRPAAADPASARQHPVGDHPGGSRSPADTAPRAQPGAGGTVPAAPPARRK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
HLVRALVAVFAFGIAGWGAWYALVGRWYETTDNAYAQGNVVELTPQVTGTVVSIDADDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCC
LVHAGTPLVRLDPSDAQVTLAAAQADLAATVRKVRGLYSNERGLANSIDGARAELAARRT
EEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
ALDKAKADYRRREDLGRSGAISHEELAHARDTLTSAQSAYAAAQSALATLSEQHQTSKAL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDDTAVASHPDVQAAASRLRAAYLARTRTDIVAPVTGYVAKRTVQVGQRVSPGVPLLAVV
HCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PLRELWVDANFTEKQLDHMRIGQPVELTADLYGSNVRYSGRVQSLGVGTGSAFSLLPAQN
CHHHHHCCCCCCHHHHHHHHCCCCCEEEHHHCCCCCEECCCEEEEECCCCCCEEEECCCC
ATGNWIKIVQRLPVRIELTDPAQLDAHPLRIGLSMHARVDQHDRSGTMLSQRVQRDPVFR
CCCHHHHHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHH
TDVYREELARADGLIADVLHANLPATARAERVR
HHHHHHHHHHHCCHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1409590; 9205837; 9278503; 8203018 [H]