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The map label for this gene is ptxR [H]

Identifier: 115351366

GI number: 115351366

Start: 1440934

End: 1441869

Strand: Direct

Name: ptxR [H]

Synonym: Bamb_1313

Alternate gene names: 115351366

Gene position: 1440934-1441869 (Clockwise)

Preceding gene: 115351364

Following gene: 115351367

Centisome position: 40.51

GC content: 72.01

Gene sequence:

>936_bases
ATGAATCAGCAAAATGTCCAGGCGCTCTGGCCGCATATCCATTCGCTGACGGTGCTCGCCGCCGCTGGCAGTTTCACGGC
CGCCGCGCAGCGGCTCGGCATCAGCAAGGCCGCGATGAGCCAGCGCATCGCCGATCTCGAGAAGGCGGCCGGCGTGCCGC
TCGTGCGGCGCACCACCCGCAGCGTGCGGCTCACCGACGCGGGGCAGACGCTGGTCGACAGCACGCGCGACGCGTTCGAG
TCGATCGGCCAGCATTTCGCGCGCGTGAAGGATCTGGCCGGCGAACCGCGCGGGCTGCTGCGCGTGACGGCGCCCGTCGC
GCTCGGGCGCCAGCAGGTGGTGCCGCACCTGCCCGATTTCCTGCGGCAGCATCCGGGCGTGCACATCGAGCTCGACCTGT
CCGACCGGCTGCATTCGCTGACGCAGGAGGGTTTCGATCTCGCGATCCGCCATACGACGACCGCGCCGCAGACCCACGTC
GCGTGGAAGCTGTGCGACACGCGTTCGCTGCTGGTCGCGAGCCGCCACTACCTCGATGCGCGCGGCGCGCCGCGCCACCC
GAGCGAACTCGTCGATCACAGCTGCCTGTGCTACCTGCGCGACAACGAGCCGGCCGCCTGGAGCTTCGAGCCCGACGGCC
GGCGTCGCCAGCGCGTGAGCGTGCCGGTGCGCGGCAGCTTCGCGGCCAACAACAGCGAGGCGATGCGCGAGGCCGCGCTC
GGCGGGCTCGGCATCGCGCTGCTGCCGGATTTCAGCGCGCAGCGCGATCTCGACGCAGGCCGGCTCGTCGCGCTGCTCGA
CGGCTGGCGGCCGTCCGGCGCGTTCGGCGACCATATCTTCGCGATCCGGCCGTACAGTCCGGTCGTGCCGAGCGCGGTGC
GCGCGCTGGTGCGGCACCTGCGCGAGCGGCTCGCCGGCGGTTTTTCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CTGGGGATGGGGGCGAATGGAGCCTAGTCTAGGCAAAGCGGCGGGGCGGGAGAAGGCCGCGCAGCTTGATTCACTGTTCA
GAATTCTGAATAATCAGTGG

Downstream 100 bases:

>100_bases
GCGGCGCGCGCGGCCGTGCCTGCCTGCCCCATGGCCGTGCCTGGGCGGCGCGGGCAGGCACGGCCGCGCTGCGGTAAAAT
CGCCGCTTCCTCCCGCGCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRVTAPVALGRQQVVPHLPDFLRQHPGVHIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRHYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPDGRRRQRVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGA

Sequences:

>Translated_311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRVTAPVALGRQQVVPHLPDFLRQHPGVHIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRHYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPDGRRRQRVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGA
>Mature_311_residues
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTRSVRLTDAGQTLVDSTRDAFE
SIGQHFARVKDLAGEPRGLLRVTAPVALGRQQVVPHLPDFLRQHPGVHIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHV
AWKLCDTRSLLVASRHYLDARGAPRHPSELVDHSCLCYLRDNEPAAWSFEPDGRRRQRVSVPVRGSFAANNSEAMREAAL
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHLRERLAGGFSGA

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=248, Percent_Identity=31.8548387096774, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789440, Length=277, Percent_Identity=29.6028880866426, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=29.1525423728814, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI145693193, Length=264, Percent_Identity=30.3030303030303, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=27, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787589, Length=262, Percent_Identity=29.7709923664122, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790011, Length=311, Percent_Identity=27.0096463022508, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789639, Length=249, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789173, Length=258, Percent_Identity=29.0697674418605, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786448, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI157672245, Length=171, Percent_Identity=30.9941520467836, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33924; Mature: 33924

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCC
SVRLTDAGQTLVDSTRDAFESIGQHFARVKDLAGEPRGLLRVTAPVALGRQQVVPHLPDF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHH
LRQHPGVHIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHVAWKLCDTRSLLVASRHYLDA
HHHCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCHHEEEEECCCHHHHHHHHHHHCC
RGAPRHPSELVDHSCLCYLRDNEPAAWSFEPDGRRRQRVSVPVRGSFAANNSEAMREAAL
CCCCCCHHHHHCCCEEEEEECCCCCEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHH
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHL
CCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RERLAGGFSGA
HHHHCCCCCCC
>Mature Secondary Structure
MNQQNVQALWPHIHSLTVLAAAGSFTAAAQRLGISKAAMSQRIADLEKAAGVPLVRRTTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCC
SVRLTDAGQTLVDSTRDAFESIGQHFARVKDLAGEPRGLLRVTAPVALGRQQVVPHLPDF
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCHHHHHHHHHHH
LRQHPGVHIELDLSDRLHSLTQEGFDLAIRHTTTAPQTHVAWKLCDTRSLLVASRHYLDA
HHHCCCCEEEEEHHHHHHHHHHCCCEEEEEECCCCCCHHEEEEECCCHHHHHHHHHHHCC
RGAPRHPSELVDHSCLCYLRDNEPAAWSFEPDGRRRQRVSVPVRGSFAANNSEAMREAAL
CCCCCCHHHHHCCCEEEEEECCCCCEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHH
GGLGIALLPDFSAQRDLDAGRLVALLDGWRPSGAFGDHIFAIRPYSPVVPSAVRALVRHL
CCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
RERLAGGFSGA
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]