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The map label for this gene is ppx [H]

Identifier: 115351238

GI number: 115351238

Start: 1297609

End: 1299123

Strand: Direct

Name: ppx [H]

Synonym: Bamb_1185

Alternate gene names: 115351238

Gene position: 1297609-1299123 (Clockwise)

Preceding gene: 115351236

Following gene: 115351240

Centisome position: 36.49

GC content: 67.26

Gene sequence:

>1515_bases
ATGGTTACATCCCCCCACTTGCTGGCTGCCGTCGATCTCGGCTCGAACAGCTTCCGGCTGATCGTCGGGCGCGTCGAGGA
AACCCCGGCGGGCAGCCAGATCTATCCCGTCGATGCGCTGCGCGAGCCCGTTCGACTGGCCGCGGGCCTGTCGAGCGACA
AGATGCTCGATCGCGCGTCGCAGGAGCGTGGCTGGGAGGCGCTCAAGCGGTTCGGCGAGCGCCTGCGCGATTTCCACCCC
GATCACGTGCGGGCGGTGGCGACCAACACGCTGCGCGTCGCGAAGAACGCGGCCGAATTCCTCGGCGAGGCCGAAGCGGC
GCTCGGTTTTCCGATCGAAGTGATCGCCGGCCGCGAAGAGGCGCGCCTGATCTACGCGGGTGCCGCGCATTCGGTGCCGG
CGAGCGCCGGCAAGCGGCTCGTCGTCGACATCGGCGGCGGCTCGACCGAATTCATCATCGGCTCGCACTACACGCCGATC
GTGATGGAGAGCCTCTACATCGGCTGCGTGAGCCACAGCCGTGCGTTCTTTCCAGCCGGCAACGTCGACGAATACACGAT
GCGGCAGGCCGAACTCGCGGCCAAGCGCGAGATCCAGATCATTTCCAGCGAGTACAAGAAGGCCGGCTGGGACCAGGCGA
TCGGTTCATCCGGCACCGCGCGTGCGCTCGCGGAGCTCGTCGAGGCGAACGGCTTCAACGACGCGGGCATCACGCACGGC
ATTTCGCGCGGCGGGCTCGAACGCCTGAAGCGTGCGCTGATCAAGTCCGAGAACGTGAACCGGCTGAAGCTGATCGCGCT
GAAGCCCGACCGCGTGCCGGTGCTCGCCGGCGGCCTCGCGATCATGCTCGCGGTATTCGAGGAACTCGGTGTCGACTATG
TCGATACCACCGACGGCGCGCTGCGTCTCGGCGTGCTGTACGACCTGCTCGGCCGGACCCAGCACGAGGACATGCGCGCG
GTGACCGTCGAGGGTTTCACGCGCCGCTACGGCGTCGATCGCGCGCAGGCCGAGCGCATTGGTGCGCTTGCGGTGCGGTT
CTACGACGAGCTCGATGAAGCCGACGACGAAGCGCGCGAGGAAGGCCGGATGTTCCTCGGCTGGGCCGCCGCGTTGCATG
AGATCGGGCTGTCGATCTCGCACAGTTCGTACCACAAGCATTCGGCCTATATCGCGAGCAACGCCGACATGCCGGGTTTC
TCGCGCACCGACCAGGCGCGGCTTGCCGCGCTCGTGCTCGGGCACGCGGGCAAGCTCGGCAAGCTGTCGCAGGCACGCGA
CGTCGAATGGCCGCTGCTGTTCTGCCTGCGGCTCGCGGCGCTGCTGTGCCGGCGCCGGACCGATGCCGGGCTGCCGGACA
TTTCCGTGTCGCAGATGAAGAAGGGCGGGTATGAAGTGCGCCTGCCGAGCGCGTGGGTCGAGCAGAACCCGCTGACCGAC
TACAGCCTCAGCCAGGAAGCGGCCGAGTGGGAGAAGGTCGGCATTCCGTATCGCGTGGTTTATACGGGCGCGTAA

Upstream 100 bases:

>100_bases
GCTACGGCAAGCGTTCCACGCTTAAAATATCGCCTTCGATTGATCGTCCAGCGTGGCCGCAGCGGCTGGCGCGGGCGAAC
GCGCACGGAGCCCCCTTCTG

Downstream 100 bases:

>100_bases
CGAGGCGGGCTTCCGGCGAGCGACACCGGCGCGGCGAGTTTGCGCTGCTTTCCTTGCGACGCGCTCAGTCCGAGCACACG
ATCGCGGTCAGGAACGGGAA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MVTSPHLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSSDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAAEFLGEAEAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGSHYTPI
VMESLYIGCVSHSRAFFPAGNVDEYTMRQAELAAKREIQIISSEYKKAGWDQAIGSSGTARALAELVEANGFNDAGITHG
ISRGGLERLKRALIKSENVNRLKLIALKPDRVPVLAGGLAIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRTQHEDMRA
VTVEGFTRRYGVDRAQAERIGALAVRFYDELDEADDEAREEGRMFLGWAAALHEIGLSISHSSYHKHSAYIASNADMPGF
SRTDQARLAALVLGHAGKLGKLSQARDVEWPLLFCLRLAALLCRRRTDAGLPDISVSQMKKGGYEVRLPSAWVEQNPLTD
YSLSQEAAEWEKVGIPYRVVYTGA

Sequences:

>Translated_504_residues
MVTSPHLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSSDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAAEFLGEAEAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGSHYTPI
VMESLYIGCVSHSRAFFPAGNVDEYTMRQAELAAKREIQIISSEYKKAGWDQAIGSSGTARALAELVEANGFNDAGITHG
ISRGGLERLKRALIKSENVNRLKLIALKPDRVPVLAGGLAIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRTQHEDMRA
VTVEGFTRRYGVDRAQAERIGALAVRFYDELDEADDEAREEGRMFLGWAAALHEIGLSISHSSYHKHSAYIASNADMPGF
SRTDQARLAALVLGHAGKLGKLSQARDVEWPLLFCLRLAALLCRRRTDAGLPDISVSQMKKGGYEVRLPSAWVEQNPLTD
YSLSQEAAEWEKVGIPYRVVYTGA
>Mature_504_residues
MVTSPHLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSSDKMLDRASQERGWEALKRFGERLRDFHP
DHVRAVATNTLRVAKNAAEFLGEAEAALGFPIEVIAGREEARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGSHYTPI
VMESLYIGCVSHSRAFFPAGNVDEYTMRQAELAAKREIQIISSEYKKAGWDQAIGSSGTARALAELVEANGFNDAGITHG
ISRGGLERLKRALIKSENVNRLKLIALKPDRVPVLAGGLAIMLAVFEELGVDYVDTTDGALRLGVLYDLLGRTQHEDMRA
VTVEGFTRRYGVDRAQAERIGALAVRFYDELDEADDEAREEGRMFLGWAAALHEIGLSISHSSYHKHSAYIASNADMPGF
SRTDQARLAALVLGHAGKLGKLSQARDVEWPLLFCLRLAALLCRRRTDAGLPDISVSQMKKGGYEVRLPSAWVEQNPLTD
YSLSQEAAEWEKVGIPYRVVYTGA

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=496, Percent_Identity=38.508064516129, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI48994966, Length=497, Percent_Identity=36.8209255533199, Blast_Score=303, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 54956; Mature: 54956

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSPHLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSSDKMLDRAS
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHH
QERGWEALKRFGERLRDFHPDHVRAVATNTLRVAKNAAEFLGEAEAALGFPIEVIAGREE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCC
ARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGSHYTPIVMESLYIGCVSHSRAFFPAG
CEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCC
NVDEYTMRQAELAAKREIQIISSEYKKAGWDQAIGSSGTARALAELVEANGFNDAGITHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCHHCC
ISRGGLERLKRALIKSENVNRLKLIALKPDRVPVLAGGLAIMLAVFEELGVDYVDTTDGA
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCEEECCCCH
LRLGVLYDLLGRTQHEDMRAVTVEGFTRRYGVDRAQAERIGALAVRFYDELDEADDEARE
HHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGRMFLGWAAALHEIGLSISHSSYHKHSAYIASNADMPGFSRTDQARLAALVLGHAGKLG
CCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KLSQARDVEWPLLFCLRLAALLCRRRTDAGLPDISVSQMKKGGYEVRLPSAWVEQNPLTD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEECCHHHHCCCCCCC
YSLSQEAAEWEKVGIPYRVVYTGA
CCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MVTSPHLLAAVDLGSNSFRLIVGRVEETPAGSQIYPVDALREPVRLAAGLSSDKMLDRAS
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHH
QERGWEALKRFGERLRDFHPDHVRAVATNTLRVAKNAAEFLGEAEAALGFPIEVIAGREE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEECCCCC
ARLIYAGAAHSVPASAGKRLVVDIGGGSTEFIIGSHYTPIVMESLYIGCVSHSRAFFPAG
CEEEEECCCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCC
NVDEYTMRQAELAAKREIQIISSEYKKAGWDQAIGSSGTARALAELVEANGFNDAGITHG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCCCHHCC
ISRGGLERLKRALIKSENVNRLKLIALKPDRVPVLAGGLAIMLAVFEELGVDYVDTTDGA
CCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCEEECCCCH
LRLGVLYDLLGRTQHEDMRAVTVEGFTRRYGVDRAQAERIGALAVRFYDELDEADDEARE
HHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGRMFLGWAAALHEIGLSISHSSYHKHSAYIASNADMPGFSRTDQARLAALVLGHAGKLG
CCCEEEHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
KLSQARDVEWPLLFCLRLAALLCRRRTDAGLPDISVSQMKKGGYEVRLPSAWVEQNPLTD
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEECCHHHHCCCCCCC
YSLSQEAAEWEKVGIPYRVVYTGA
CCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]