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The map label for this gene is phoR [H]

Identifier: 115351236

GI number: 115351236

Start: 1293823

End: 1295142

Strand: Direct

Name: phoR [H]

Synonym: Bamb_1183

Alternate gene names: 115351236

Gene position: 1293823-1295142 (Clockwise)

Preceding gene: 115351235

Following gene: 115351238

Centisome position: 36.38

GC content: 65.61

Gene sequence:

>1320_bases
ATGAACATCATCTGGGCGCGCTTTCTCGTGTCGCTCGTGCTGCTCGTGCTGATCAGCGTATTGGTCGGCGTGTTCGCCGG
CCCGACCGCGGCCTGCGGGTTCGCGGCCGTGATGCTGGTCGCGCAGGGCTTCTTCAGTACCTTCCATACGCAACGCCTGT
GGCGTCTGCTCGATGCGCCCGTCTACGGCGAGGTGCCGAGCGCACCGGGCATCTGGGGTGAAATCTATTACCGGCTGCAC
AAGCTCGCGAAGCAGTGGCATGCGCAGGTGCGGCAGGTCGAGCAGCAGCATTCGCGCTTCATCCAGGCGATCCAGGCGTC
GCCGAACGGCGTCGCGATGCTCGACGACCACGACCAGATCGAGTGGTGCAACGCGATCGCCGAGGTGCATTTCGGCCTCG
ATGCGAAACGCGACCTGCGCCAGCACATCACGAACCTCGTGCGTCATCCGGAATTCGTCCGCTACCTGAACGCGCAGCAC
TACGACGAAACGCTCGTGATGCGCGGGATGGGCGACTCGCGGCAGAACGTGCTGGAGGTGCAGGTGTTTCCGTACGGCGA
GAACCGCAAGCTGCTGCTCACGCAGGACATCACCGAGCTCGAGCGGACCGACGCGATGCGCCGCGACTTCGTCGCGAACG
TGTCGCACGAACTGAAGACGCCGCTCACCGTGCTGTCGGGTTTTCTCGAGACGATGCGTGAGCTGCCGCTGAACGAGGAA
GATCGCGCGCGCTATCTCGAGATGATGGAGCAGCAGGCGTCGCGGATGCGGCACATCGTCACCGACCTGCTGGTGCTCGC
GAAGCTCGAGGGCGAAAGCCGGCCGCCGGTCGATCACGCGATCGACATGCGCGCCGTGTTCGACCATCTGAAGGAGGATG
CGCAGACGCTGTCGAACGGGCATCACGAGATCGCGTTCGCGATCGACGAGACGCTCGGCGTCACGGGCGCGCAGACCGAA
GTGTTCAGCGCGTTCGCGAATCTCGTCACCAACGCGATCCGCTATACGCCGGACGGCGGCAAGATATTCGTGTCGTGGCG
GCGCGAGGGCGCGCAGGGCGTGTTCTCCGTCACCGACAGTGGCTTCGGCATTCCGGCCGCCGACCTGCCGCGGTTGACGG
AGCGCTTCTATCGCGTCGACCGCAGCCGTTCGCGCGATACGGGCGGCACGGGCCTCGGCCTCGCGATCGTCAAGCACGTG
CTGCAGCGGCACGACTCGCACCTGTATGTGCAGAGCGAGGAAGGACGCGGCAGCACGTTCACCGCGCGCTTCCCGGCGTC
GCGGATCATCGCGATCCGGCCGGCAGCGTTCGAAGCTTGA

Upstream 100 bases:

>100_bases
GACCGTGCGCGGCAGCGGCTACCGGCTCGCCAAGCACGCGTAACGTATCCGCGCATGCCGTGTGCCACGGCATGCCGTTC
ATTCTTTCGGGCGCTGAATC

Downstream 100 bases:

>100_bases
GCGCGTGATCGTGTGACACGGTTCGTGCGCATCGCATCCGCGCACGACCGAAACGAAAAAGGCACAGCCCGCGTGGGCTG
TGCCTTTTTCGTTTGCTGCG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNIIWARFLVSLVLLVLISVLVGVFAGPTAACGFAAVMLVAQGFFSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAEVHFGLDAKRDLRQHITNLVRHPEFVRYLNAQH
YDETLVMRGMGDSRQNVLEVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLNEE
DRARYLEMMEQQASRMRHIVTDLLVLAKLEGESRPPVDHAIDMRAVFDHLKEDAQTLSNGHHEIAFAIDETLGVTGAQTE
VFSAFANLVTNAIRYTPDGGKIFVSWRREGAQGVFSVTDSGFGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDSHLYVQSEEGRGSTFTARFPASRIIAIRPAAFEA

Sequences:

>Translated_439_residues
MNIIWARFLVSLVLLVLISVLVGVFAGPTAACGFAAVMLVAQGFFSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAEVHFGLDAKRDLRQHITNLVRHPEFVRYLNAQH
YDETLVMRGMGDSRQNVLEVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLNEE
DRARYLEMMEQQASRMRHIVTDLLVLAKLEGESRPPVDHAIDMRAVFDHLKEDAQTLSNGHHEIAFAIDETLGVTGAQTE
VFSAFANLVTNAIRYTPDGGKIFVSWRREGAQGVFSVTDSGFGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDSHLYVQSEEGRGSTFTARFPASRIIAIRPAAFEA
>Mature_439_residues
MNIIWARFLVSLVLLVLISVLVGVFAGPTAACGFAAVMLVAQGFFSTFHTQRLWRLLDAPVYGEVPSAPGIWGEIYYRLH
KLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQIEWCNAIAEVHFGLDAKRDLRQHITNLVRHPEFVRYLNAQH
YDETLVMRGMGDSRQNVLEVQVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLNEE
DRARYLEMMEQQASRMRHIVTDLLVLAKLEGESRPPVDHAIDMRAVFDHLKEDAQTLSNGHHEIAFAIDETLGVTGAQTE
VFSAFANLVTNAIRYTPDGGKIFVSWRREGAQGVFSVTDSGFGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHV
LQRHDSHLYVQSEEGRGSTFTARFPASRIIAIRPAAFEA

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=427, Percent_Identity=36.768149882904, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI145693157, Length=344, Percent_Identity=27.6162790697674, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=28.4046692607004, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=375, Percent_Identity=26.4, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786783, Length=259, Percent_Identity=32.046332046332, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=31.7391304347826, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=31.4814814814815, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.004329004329, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=26, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=391, Percent_Identity=23.0179028132992, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=24.901185770751, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=254, Percent_Identity=28.3464566929134, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789403, Length=225, Percent_Identity=27.1111111111111, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=31.6742081447964, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49570; Mature: 49570

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIWARFLVSLVLLVLISVLVGVFAGPTAACGFAAVMLVAQGFFSTFHTQRLWRLLDAP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAEVHFGLDAKRDLRQHITNLVRHPEFVRYLNAQHYDETLVMRGMGDSRQNVLEV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEE
QVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLNEE
EEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
DRARYLEMMEQQASRMRHIVTDLLVLAKLEGESRPPVDHAIDMRAVFDHLKEDAQTLSNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HHEIAFAIDETLGVTGAQTEVFSAFANLVTNAIRYTPDGGKIFVSWRREGAQGVFSVTDS
CCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCEEEECCC
GFGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDSHLYVQSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
TARFPASRIIAIRPAAFEA
EEECCCCCEEEECCHHCCC
>Mature Secondary Structure
MNIIWARFLVSLVLLVLISVLVGVFAGPTAACGFAAVMLVAQGFFSTFHTQRLWRLLDAP
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VYGEVPSAPGIWGEIYYRLHKLAKQWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
EWCNAIAEVHFGLDAKRDLRQHITNLVRHPEFVRYLNAQHYDETLVMRGMGDSRQNVLEV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEE
QVFPYGENRKLLLTQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLNEE
EEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
DRARYLEMMEQQASRMRHIVTDLLVLAKLEGESRPPVDHAIDMRAVFDHLKEDAQTLSNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HHEIAFAIDETLGVTGAQTEVFSAFANLVTNAIRYTPDGGKIFVSWRREGAQGVFSVTDS
CCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCEEEECCC
GFGIPAADLPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDSHLYVQSEEGRGSTF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
TARFPASRIIAIRPAAFEA
EEECCCCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]