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The map label for this gene is galE [H]

Identifier: 115350814

GI number: 115350814

Start: 844540

End: 845457

Strand: Direct

Name: galE [H]

Synonym: Bamb_0760

Alternate gene names: 115350814

Gene position: 844540-845457 (Clockwise)

Preceding gene: 115350813

Following gene: 115350815

Centisome position: 23.75

GC content: 63.29

Gene sequence:

>918_bases
ATGAGCGCGGCTTCTCGTTCTGATGTCCCGCGCGCGCTGGTAACGGGCCTCGGCGGCTTTACCGGCGACTATCTCGCGGA
GTCGCTGCGGGCGGCCGGGTATCGCGTGTTCGGCACGACACACGCGGCCGACACGATCGAACCCGATACGTATCGGGTCG
ATCTGTGCGACCGGCCGACGCTCGCGGACGTCGTCGCGGAAGTGCAGCCCGACATCGTCGCGCATCTTGCGGCGGTGTCG
TTCGTCGCCCACGGCGACGCGGACGCGATCTATCGTACCAACGTGGTCGGTACACGGAACCTGTTGGAAGCGCTCGCGAA
TCTGGAGAATCGTCCACGCGCGGTTTTGCTGGCGAGCAGTGCGAACATCTATGGCAACGCGGCGGTCGAGATCATCGACG
AATCGATCGAGCCGAATCCCGCCAACGATTACGCCGTCAGCAAGCTGGCGATGGAATACATGGCGCGCCTGTGGCGCGAT
AAGCTGCCGATTGTCATCGCGCGGCCGTTCAACTACACGGGCGTCGGGCAGTCGCCGCAGTTTTTGCTGCCGAAGATCGT
CGGTCACTTCCAGCGGGGCGAGCGTGTGATCGAACTTGGCAATATCGACGTCGAGCGAGATTTTTCCGACGTACGTCGCG
TGGCGGACGCCTATCGGCGACTACTGGAGTTGTCGCCGGCCGGCGGTGTGTTCAACGTCTGTTCGGGGCGCGCGGTGTCG
CTGAAAGCGGTGATCTCGATGATGGAACGGATTGCCGGCTATGCGATCGAGGTACGCGTCAATCCCGCATTCGTACGCGC
GAACGACGTGCGTCGACTGCAGGGCAACGATGCGCGGTTGCAGGCTGCCATCGGGCCGCTTGAGGACATTCCGCTGGAGA
ACACATTGCGCTGGATGTTCGAAGAGGGGCGTGGGTGA

Upstream 100 bases:

>100_bases
ATCGGGAATCCCGAGAAGGCGAAGCAGAAGCTGGGCTGGGAGCCGAAGACGACGCTCGAGGAGCTGTGTGCGATGATGGT
TGAAGCGGACTTGCGACGAA

Downstream 100 bases:

>100_bases
CAGTCAGTCTCGGTCCGGGGGCATTGGCACCGCGCAGTGCGTCAGTTTCGCCGGGGCAGTGTTTGCGGTTTGTCGAACAT
GCAGGGCACGGCGAGGTGTC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSAASRSDVPRALVTGLGGFTGDYLAESLRAAGYRVFGTTHAADTIEPDTYRVDLCDRPTLADVVAEVQPDIVAHLAAVS
FVAHGDADAIYRTNVVGTRNLLEALANLENRPRAVLLASSANIYGNAAVEIIDESIEPNPANDYAVSKLAMEYMARLWRD
KLPIVIARPFNYTGVGQSPQFLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVADAYRRLLELSPAGGVFNVCSGRAVS
LKAVISMMERIAGYAIEVRVNPAFVRANDVRRLQGNDARLQAAIGPLEDIPLENTLRWMFEEGRG

Sequences:

>Translated_305_residues
MSAASRSDVPRALVTGLGGFTGDYLAESLRAAGYRVFGTTHAADTIEPDTYRVDLCDRPTLADVVAEVQPDIVAHLAAVS
FVAHGDADAIYRTNVVGTRNLLEALANLENRPRAVLLASSANIYGNAAVEIIDESIEPNPANDYAVSKLAMEYMARLWRD
KLPIVIARPFNYTGVGQSPQFLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVADAYRRLLELSPAGGVFNVCSGRAVS
LKAVISMMERIAGYAIEVRVNPAFVRANDVRRLQGNDARLQAAIGPLEDIPLENTLRWMFEEGRG
>Mature_304_residues
SAASRSDVPRALVTGLGGFTGDYLAESLRAAGYRVFGTTHAADTIEPDTYRVDLCDRPTLADVVAEVQPDIVAHLAAVSF
VAHGDADAIYRTNVVGTRNLLEALANLENRPRAVLLASSANIYGNAAVEIIDESIEPNPANDYAVSKLAMEYMARLWRDK
LPIVIARPFNYTGVGQSPQFLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVADAYRRLLELSPAGGVFNVCSGRAVSL
KAVISMMERIAGYAIEVRVNPAFVRANDVRRLQGNDARLQAAIGPLEDIPLENTLRWMFEEGRG

Specific function: Biosynthesis of the slime polysaccharide colanic acid. First of the three steps in the biosynthesis of GDP-fucose from GDP-mannose. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=249, Percent_Identity=27.710843373494, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788366, Length=349, Percent_Identity=27.2206303724928, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994969, Length=255, Percent_Identity=28.6274509803922, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788353, Length=259, Percent_Identity=27.7992277992278, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133901786, Length=323, Percent_Identity=26.9349845201238, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133901788, Length=323, Percent_Identity=26.9349845201238, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539424, Length=323, Percent_Identity=26.9349845201238, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539422, Length=323, Percent_Identity=26.9349845201238, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133901790, Length=323, Percent_Identity=26.9349845201238, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=324, Percent_Identity=24.6913580246914, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=187, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33353; Mature: 33222

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASRSDVPRALVTGLGGFTGDYLAESLRAAGYRVFGTTHAADTIEPDTYRVDLCDRPT
CCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCCCCH
LADVVAEVQPDIVAHLAAVSFVAHGDADAIYRTNVVGTRNLLEALANLENRPRAVLLASS
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEEEC
ANIYGNAAVEIIDESIEPNPANDYAVSKLAMEYMARLWRDKLPIVIARPFNYTGVGQSPQ
CCCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCH
FLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVADAYRRLLELSPAGGVFNVCSGRAVS
HHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHH
LKAVISMMERIAGYAIEVRVNPAFVRANDVRRLQGNDARLQAAIGPLEDIPLENTLRWMF
HHHHHHHHHHHCCEEEEEEECCEEEECCCHHHHCCCCCEEEEECCCHHCCCHHHHHHHHH
EEGRG
HCCCC
>Mature Secondary Structure 
SAASRSDVPRALVTGLGGFTGDYLAESLRAAGYRVFGTTHAADTIEPDTYRVDLCDRPT
CCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEECCCCCH
LADVVAEVQPDIVAHLAAVSFVAHGDADAIYRTNVVGTRNLLEALANLENRPRAVLLASS
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCEEEEEEC
ANIYGNAAVEIIDESIEPNPANDYAVSKLAMEYMARLWRDKLPIVIARPFNYTGVGQSPQ
CCCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCH
FLLPKIVGHFQRGERVIELGNIDVERDFSDVRRVADAYRRLLELSPAGGVFNVCSGRAVS
HHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHH
LKAVISMMERIAGYAIEVRVNPAFVRANDVRRLQGNDARLQAAIGPLEDIPLENTLRWMF
HHHHHHHHHHHCCEEEEEEECCEEEECCCHHHHCCCCCEEEEECCCHHCCCHHHHHHHHH
EEGRG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]