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The map label for this gene is pcaR [H]

Identifier: 115350749

GI number: 115350749

Start: 771537

End: 772328

Strand: Direct

Name: pcaR [H]

Synonym: Bamb_0695

Alternate gene names: 115350749

Gene position: 771537-772328 (Clockwise)

Preceding gene: 115350747

Following gene: 115350750

Centisome position: 21.69

GC content: 69.32

Gene sequence:

>792_bases
ATGACACTTTCAACCATCGACGAAACCACGATCGACGAACGCAAGTTCGTCGTTGCGCTCGCGCGCGGGCTCGACCTGCT
GCGCGCGTTCCGGCCCGGCGAGACGATGCTCGGCAATCGCGACTTCGCGGAGCGCACCGGGCTGCCGAAGGCGACGGTGA
ACCGGCTCGCGTACACGCTGACCGTGCTCGGCTACCTGCGCTATGACGAAACGCTCGGAAAGTATGCGCTCGACGCCGGC
GTGCTGTCGCTCGGCTACGCGCTGCTGTCCGGCTCGGGGACGATCGATCTCGCGCGGCCGCACATGCAGGCGCTCGCGCG
TGAAATCGGCGCGGCCGTGTCGCTCGGCTGCCGCGACGGGCTCGACATGATCTACCTGGAGACGATCCGCAGCGAAACCG
CGCTGACGCTCGGGCTTGCGCCCGGCTCGCGACTGTCGATGCTGACGAGCTCGATGGGCCGCGCGTACCTCGCCGTGCAG
CCGGAGGACGTGCGCCGCGCGCTTTATGCGGAGCTGCACCGGGCGGCCGGCGGCGCGGCCGACGCGGATGCGCTCGTCGC
GGCCGCGCAGCTTGCGGTGGCCGAGTTCTCCGAGGGCGGATGCTGCTATTCGTTTCGCGCGTGGCACATGGACGTGAACG
CGGCGGCCGTGCCGTTTCGCGAGCCGCGCGAGGGGCGCTGGCTGATTTTGAGTTGCAGCGGGCCCGCATCGTCGATGGAC
GAGCACGTGTTCCGTACGCAGGTCGGCCCAAAGCTTAAGGCGCTCGCGCAGCGGCTCGGGCAAACGGTCTGA

Upstream 100 bases:

>100_bases
GGTTGGCGCTTCGACGCCTTGCCCGATGTCTAAAGTTCGCTTGACTATAGTTCCGCTGTGCGGAACAATGTTTTGCAAAA
CGAACCCAGTGTAGCATCAG

Downstream 100 bases:

>100_bases
GTGGGGTGCCGCGAGCCCGCGCGTCACCCGGGTTCTGCGGAACGGGGAAGCGCGCAGCCGCCGGTTGCACCGCGTGCGAA
CCGCGCTCATCATCGTTCGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRAAGGAADADALVAAAQLAVAEFSEGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
EHVFRTQVGPKLKALAQRLGQTV

Sequences:

>Translated_263_residues
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRAAGGAADADALVAAAQLAVAEFSEGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
EHVFRTQVGPKLKALAQRLGQTV
>Mature_262_residues
TLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAGV
LSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQP
EDVRRALYAELHRAAGGAADADALVAAAQLAVAEFSEGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMDE
HVFRTQVGPKLKALAQRLGQTV

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=230, Percent_Identity=26.5217391304348, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28315; Mature: 28184

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRAAGGAA
CHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQLAVAEFSEGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEECCCCCCCCCCEEEEECCCCCCHHH
EHVFRTQVGPKLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLSTIDETTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRAAGGAA
CHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQLAVAEFSEGGCCYSFRAWHMDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEECCCCCCCCCCEEEEECCCCCCHHH
EHVFRTQVGPKLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]