Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 115350540

GI number: 115350540

Start: 549541

End: 550653

Strand: Direct

Name: obgE

Synonym: Bamb_0486

Alternate gene names: 115350540

Gene position: 549541-550653 (Clockwise)

Preceding gene: 115350539

Following gene: 115350541

Centisome position: 15.45

GC content: 67.03

Gene sequence:

>1113_bases
ATGAAGTTCATTGACGAAGCACGAATCGAAGTCATCGCCGGCGACGGAGGTGATGGGAGCGCGTCGATGCGCCGCGAAAA
GTTCGTTCCGTTCGGCGGGCCGGACGGCGGCGACGGCGGCCGGGGCGGCAACGTCTACGCGATTGCCGACCGCAACATCA
ACACGCTGATCGACTACCGTTACGCGAAGAAGCACCTGGCGCGCAACGGCGAAAACGGTCGCGGCTCGGATTGCTACGGC
AAGGGCGGTGACGACGTCACGCTGCGCATGCCGGTCGGCACGGTCGTGACCGACATGGATACCGGCGAGCTGATCGCCGA
CCTGACCGAGCACGGCCAGCAGGTGATGCTTGCGCAAGGCGGTGCCGGCGGCCTCGGCAACCTGCATTTCAAGTCGAGCA
CGAACCGTGCGCCGCGCCAGAAGACCGACGGCAAGCCGGGCGAACGGCGCATGCTGCGGCTCGAGCTGAAGGTGCTCGCC
GACGTCGGGCTGCTCGGCATGCCGAACGCAGGCAAGTCGACCTTCATCTCGTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGACTATCCGTTTACGACGCTCGCGCCGAACCTCGGCGTCGTGCGGGTCGGCCCGAGCAAGAGTTTTGTGATCGCCGACA
TCCCGGGGCTGATCGAGGGCGCCGCCGAAGGCGCGGGCCTCGGCCACCAGTTCCTGCGACATCTGCAGCGCACGGGCGTG
CTGCTGCATCTCGTCGATCTGGCCCCGTTCGACGAAAACGTCGACCCGGTCGCGGAAGCGAGGGCAATCGTCGGCGAACT
GCGCAAGTACGACGAGGCGCTCTACGAGAAGCCGCGCTGGCTCGTCCTCAACAAGCTCGACATGGTGCCGGAAGACGAGC
GTGAAGCGCGCGTCGCCGATTTCCTCGCCCGCTTCGAGTGGGACGGCCCGGTATTCGAGATTTCGGCGCTGACGGGCCAG
GGCTGCGAAGCGCTGTGCTACGCGATCTACGATTACCTCGCCGAGCATTCGGACGCGCATCGCGCGGCGGAAGAGGAAGA
TCTGGCCACGGACGTGCGGTTCCGCGACGCGCCGCCCGCCGATGGCGGGGCGACGCCCGGCGACGACGCCTGA

Upstream 100 bases:

>100_bases
CCGGCGGCTGTCGCGAAGCGGCGGGCAATCGGCCGAACGGCAGATTGTTCAAGCGTGCCGGCGCGCGGCACAATAGCGGA
AATACTGGTCGGAGTAACGA

Downstream 100 bases:

>100_bases
GCGGACCCGAAACGCACCGGGCATCGCGCCCGGTGCCGGAATTCAATCGCGCCCGGCCGGGCAGGCATCAGATACAGGAG
ACGGCGCACGATGCGTTCGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGNVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTVVTDMDTGELIADLTEHGQQVMLAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDENVDPVAEARAIVGELRKYDEALYEKPRWLVLNKLDMVPEDEREARVADFLARFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEEEDLATDVRFRDAPPADGGATPGDDA

Sequences:

>Translated_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGNVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTVVTDMDTGELIADLTEHGQQVMLAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDENVDPVAEARAIVGELRKYDEALYEKPRWLVLNKLDMVPEDEREARVADFLARFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEEEDLATDVRFRDAPPADGGATPGDDA
>Mature_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGNVYAIADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDVTLRMPVGTVVTDMDTGELIADLTEHGQQVMLAQGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDENVDPVAEARAIVGELRKYDEALYEKPRWLVLNKLDMVPEDEREARVADFLARFEWDGPVFEISALTGQ
GCEALCYAIYDYLAEHSDAHRAAEEEDLATDVRFRDAPPADGGATPGDDA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=39.2857142857143, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI111955139, Length=393, Percent_Identity=33.8422391857506, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI111955063, Length=227, Percent_Identity=34.8017621145374, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=31.6176470588235, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=354, Percent_Identity=57.0621468926554, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=339, Percent_Identity=37.4631268436578, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=30.2469135802469, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=197, Percent_Identity=38.5786802030457, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321773, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=41.2162162162162, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI20129375, Length=337, Percent_Identity=37.0919881305638, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39780; Mature: 39780

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGNVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDVTLRMPVGTVVTDMDTGELIADLTEHGQQVMLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDENVDPVAEARAIVGELRKYDEALYEKPRWLVLNKLDMVPEDEREARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
FLARFEWDGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEEEDLATDVRFRDAPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCC
DGGATPGDDA
CCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGNVYAIADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDVTLRMPVGTVVTDMDTGELIADLTEHGQQVMLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDENVDPVAEARAIVGELRKYDEALYEKPRWLVLNKLDMVPEDEREARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
FLARFEWDGPVFEISALTGQGCEALCYAIYDYLAEHSDAHRAAEEEDLATDVRFRDAPPA
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCC
DGGATPGDDA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA