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The map label for this gene is murC

Identifier: 115350518

GI number: 115350518

Start: 526537

End: 527934

Strand: Direct

Name: murC

Synonym: Bamb_0464

Alternate gene names: 115350518

Gene position: 526537-527934 (Clockwise)

Preceding gene: 115350517

Following gene: 115350519

Centisome position: 14.8

GC content: 68.88

Gene sequence:

>1398_bases
ATGAAACACATCGTCAAACAGATTCATTTCGTCGGGATCGGCGGCGCGGGCATGAGCGGCATCGCCGAAGTGCTCGTCAA
CCTCGGCTACGAGGTCAGCGGCTCGGACCTGTCGCGCAACGCGGTGACCGATCGTCTTGAGGCGCTCGGCGCGCGGATCG
CGATCGGCCACGACGCGGCGAACATCGCGGGCGCGAACGCGGTCGTCGTGTCGACGGCCGTGCGCTCGGACAATCCCGAA
GTCCTGGCCGCACGGCACCAGGGCGTGCCGATCGTGCAGCGCGCGGTGATGCTCGCGGAGCTGATGCGCCTGAAGCAGGG
GATCGCGATTGCCGGCACGCACGGCAAGACCACGACGACGAGCCTCGTCGCGAGCGTGCTCGCGGCGGGCGGCCTCGATC
CGACCTTCGTGATCGGCGGCCGGCTGATCAGCGCCGGCGCGAACGCGCGGCTCGGCACGGGCGACTTCATCGTCGCCGAG
GCCGACGAGTCGGACGCGTCGTTCCTGAACCTGTATCCGGTGATCGAAGTCATCACGAACATCGACGCCGACCACATGGA
CACCTACGGCCACGATTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACGCAGCGCCTGCCGTTCTACGGCAGCGCGG
TCGTGTGCGTCGACGATCCGAACGTGCGGCAGATCATCCCGTTCATCTCGAAGCCGGTCGTGCGCTACGGCCTGTCGCCG
GATGCGCAGGTGCGCGCCGAAGACATCGACGCGCGCGACGGCCGCATGCACTTCACGGTGATCCGCGAAGGTCGTGCGCC
GCTCGCGGTGGTGCTGAACCTGCCGGGCCTGCACAACGTACAGAACGCGCTCGCGGCGATCGCGATCGCGACCGATCTCG
GCGTGTCGGACGACGCGATCCAGCAGGCGCTGGCGGAATTCAACGGCGTCGGCCGGCGCTTCCAGCGCTACGGCGAGGTG
CCGAGCGCGGACGGCGGCCAGTACACGCTGATCGACGACTACGGCCACCACCCGGTCGAGATGGCCGCGACGGTCGCGGC
CGCGCGCGGCGCGTTTCCGGGCCGCCGCCTCGTGCTGGCGTTCCAGCCGCACCGCTACACGCGCACGCGCGACTGTTTCG
ACGACTTCGTCAACGTGCTGTCGACGGTCGACGCGCTGGTGCTGACGGAAGTCTATGCCGCCGGCGAAGCGGCGATCACG
ACGGCCAACGGCGACGCGCTGTCGCGTGCGCTGCGTGCGGTGGGGAGGGTCGACCCGGTGTTCGTCGCGTCGGTCGACGA
CGTGCCGGACGCCCTGGCGGGAGTCGCCCGGAACGGCGACGTGGTGATCACGATGGGCGCGGGTTCGATCGGCGGCGTGC
CGGCGAAGATCGTGCAACACATTCAACAGAAGGCATGA

Upstream 100 bases:

>100_bases
ACATGGCGGAGCGTTCGCGCTCGCTGGCCAAGCCCGAGGCCACCGACGAAGTCGCGCGCATCTGCGCGACGGTGGCCGGC
GCGAACCTGGAAGAAATCAA

Downstream 100 bases:

>100_bases
CATGAGCGGAATCGATCCGAAACGTTTCGGCAAGGTGGCAGTGTTGTTCGGCGGCGAATCCGCCGAGCGCGAGGTGTCGC
TCACCTCGGGCCGCCTCGTG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKHIVKQIHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTDRLEALGARIAIGHDAANIAGANAVVVSTAVRSDNPE
VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGEV
PSADGGQYTLIDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIT
TANGDALSRALRAVGRVDPVFVASVDDVPDALAGVARNGDVVITMGAGSIGGVPAKIVQHIQQKA

Sequences:

>Translated_465_residues
MKHIVKQIHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTDRLEALGARIAIGHDAANIAGANAVVVSTAVRSDNPE
VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGEV
PSADGGQYTLIDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIT
TANGDALSRALRAVGRVDPVFVASVDDVPDALAGVARNGDVVITMGAGSIGGVPAKIVQHIQQKA
>Mature_465_residues
MKHIVKQIHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTDRLEALGARIAIGHDAANIAGANAVVVSTAVRSDNPE
VLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAE
ADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGEV
PSADGGQYTLIDDYGHHPVEMAATVAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIT
TANGDALSRALRAVGRVDPVFVASVDDVPDALAGVARNGDVVITMGAGSIGGVPAKIVQHIQQKA

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=453, Percent_Identity=53.4216335540839, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1790680, Length=481, Percent_Identity=29.1060291060291, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 48979; Mature: 48979

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKQIHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTDRLEALGARIAIGHDAA
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCEEEECCCCH
NIAGANAVVVSTAVRSDNPEVLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT
HCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAI
CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHH
QQALAEFNGVGRRFQRYGEVPSADGGQYTLIDDYGHHPVEMAATVAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAITTANGDALSRALRAVGRVDPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCE
FVASVDDVPDALAGVARNGDVVITMGAGSIGGVPAKIVQHIQQKA
EEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKHIVKQIHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTDRLEALGARIAIGHDAA
CCHHHHHHHEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCEEEECCCCH
NIAGANAVVVSTAVRSDNPEVLAARHQGVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTT
HCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSP
CCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCHHHHHCCCC
DAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAI
CCCEECCCCCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHH
QQALAEFNGVGRRFQRYGEVPSADGGQYTLIDDYGHHPVEMAATVAAARGAFPGRRLVLA
HHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEE
FQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAITTANGDALSRALRAVGRVDPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCE
FVASVDDVPDALAGVARNGDVVITMGAGSIGGVPAKIVQHIQQKA
EEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA