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The map label for this gene is murA [H]

Identifier: 115350396

GI number: 115350396

Start: 385165

End: 386514

Strand: Direct

Name: murA [H]

Synonym: Bamb_0341

Alternate gene names: 115350396

Gene position: 385165-386514 (Clockwise)

Preceding gene: 115350395

Following gene: 115350397

Centisome position: 10.83

GC content: 68.89

Gene sequence:

>1350_bases
GTGCAAGTCACCGTCAACGAGCGCGACGCCGTCCAGAGCGTCGCCACGGCACACCCGGCCGCCAACGGGGAATCGCAGGG
ACACGGGATGGACAAGCTGGTGGTCGAGGGCGGTCGCCGGCTTTCGGGCGAGATCGTCGTGTCGGGCGCGAAGAATGCCG
CGCTGCCGATCCTGTGCGCGGGGCTGCTCAGCGCCGAGCCGGTCGAGCTCGACAACGTGCCGAACCTGAAGGACGTGCGC
ACCACGCTGAAGGTACTGAACCAGATGGGCGTGAAGAGCGAAACGGACGGCTGCCGCGTGCAGCTCGACGCGTCGCGCGT
CGACAACCTCGTCGCGCCGTACGAGCTCGTCAAGACGATGCGCGCGTCGATTCTCGTGCTCGGGCCGCTGCTCGCGCGCT
TCGGCGAGGCGAAGGTGTCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGTCCGGTCGACCAGCACATCAAGGGCCTGCAG
GCGATGGGCGCCGAGATCAGCATCGAGCACGGCTTCATCGAAGCGCGCGCGAAGCGCCTGAAGGGCGCGCGCATCGTGAC
CGACATGATCACGGTGACGGGGACGGAAAACCTGCTGATGGCCGCGACGCTGGCCGACGGCGAGACGGTGATCGAGAACG
CGGCGCGCGAGCCGGAAGTGAGCGATCTCGCACACTTGCTGGTCGCGATGGGCGCGAAAATCTCGGGCATCGGCACCGAT
CGCCTGGTGATCCAGGGCGTCGAGCGGCTGCACGGCGCACGCCATTCGGTGATTCCCGACCGCATCGAGGCCGGCACGTT
CCTGTGCGCGGTCGCGGCGGCCGGCGGCGACGTGCTGCTGACGGGCGTGCGCCCGCACATCCTCGACGCGGTGATCGACA
AGCTGCGCGAGGCCGGCGTGTCGATCGAGGAAGGCGACAGCTGGCTGCGCGTGCGGATGGACCGCCGCCCGTCGGCGGTG
ACGATCCGCACGTCGGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATGGCCCTCAATTCGGTCGCGACGGG
CACCGCGCAGATCGTCGAGACCATCTTCGAGAACCGCTTCATGCACGTGCAGGAGCTGAACCGGCTCGGCGCGAACATCA
CGATCGACGGCAACACCGCGCTCGTGACGGGCGTCGACAAGCTGTCCGGCGCGAACGTGATGGCGACCGACCTGCGCGCA
TCGGCGAGCCTCGTGATCGCCGGGCTGCGCGCCGAAGGCGAAACGCTCGTCGACCGCATCTATCACCTGGACCGCGGCTA
CGACCGCATGGAAACCAAACTGACCGCCGTCGGCGCGAACGTGCGCCGCCTCTCCGGGAGCCAAGCATGA

Upstream 100 bases:

>100_bases
TATGCGGCGCTCGGCGATCGCATGAAACAGGAAATCCACGCGCTCAGCATGAAGACGCTGACGCCCGCCGAATGGCAGAA
CGCATAACCGGAACCACTGA

Downstream 100 bases:

>100_bases
CCGCGCCGCTGACCCTCGCCCTGTCGAAGGGCCGGATTTTCGAGGAAACCCTGCCGCTGCTCGCCGCCGCCGGCGTGCAG
GTGGCCGAGGATCCGGAAAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQVTVNERDAVQSVATAHPAANGESQGHGMDKLVVEGGRRLSGEIVVSGAKNAALPILCAGLLSAEPVELDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKISGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVLLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVRMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQIVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETLVDRIYHLDRGYDRMETKLTAVGANVRRLSGSQA

Sequences:

>Translated_449_residues
MQVTVNERDAVQSVATAHPAANGESQGHGMDKLVVEGGRRLSGEIVVSGAKNAALPILCAGLLSAEPVELDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKISGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVLLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVRMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQIVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETLVDRIYHLDRGYDRMETKLTAVGANVRRLSGSQA
>Mature_449_residues
MQVTVNERDAVQSVATAHPAANGESQGHGMDKLVVEGGRRLSGEIVVSGAKNAALPILCAGLLSAEPVELDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKISGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVLLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVRMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQIVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETLVDRIYHLDRGYDRMETKLTAVGANVRRLSGSQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=60.1431980906921, Blast_Score=505, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47677; Mature: 47677

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTVNERDAVQSVATAHPAANGESQGHGMDKLVVEGGRRLSGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCEECCEEEEECCCCCCHHHHHH
GLLSAEPVELDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKISGIGTD
CCCEEEEHEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCH
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVLLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCC
SIEEGDSWLRVRMDRRPSAVTIRTSEYPAFPTDMQAQFMALNSVATGTAQIVETIFENRF
CEECCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETLVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEHHHHCCCEEEEEECCCCCHHHHHHH
YHLDRGYDRMETKLTAVGANVRRLSGSQA
HHHCCCHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MQVTVNERDAVQSVATAHPAANGESQGHGMDKLVVEGGRRLSGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCEECCEEEEECCCCCCHHHHHH
GLLSAEPVELDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKISGIGTD
CCCEEEEHEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCH
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVLLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCC
SIEEGDSWLRVRMDRRPSAVTIRTSEYPAFPTDMQAQFMALNSVATGTAQIVETIFENRF
CEECCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETLVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEHHHHCCCEEEEEECCCCCHHHHHHH
YHLDRGYDRMETKLTAVGANVRRLSGSQA
HHHCCCHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA