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The map label for this gene is 116249341

Identifier: 116249341

GI number: 116249341

Start: 728541

End: 729863

Strand: Direct

Name: 116249341

Synonym: pRL120678

Alternate gene names: NA

Gene position: 728541-729863 (Clockwise)

Preceding gene: 116249339

Following gene: 116249342

Centisome position: 83.74

GC content: 62.21

Gene sequence:

>1323_bases
GTGACGAGTTCGGAACGCCAGCCGGAAAATCCGGCATCGGGAGGGGCGGAGAAACACGCCTGGTTCAGCCAGGATCGCCT
GGGCATGTTCATCCATTGGGGCCTCTATGCCTTGGGAGCCCGGCACGAGTGGTTGAAGAACCGCGAAGAGCTGACCGACG
AGCATTACCAGCGCTATTTCGACAATTTCGATCCCGATCTCTACGATCCCAAGGAATGGGCCCGCCGGGCGCGCCTTGCC
GGCATGAAATATGTCGTGGTGACGACCAAGCATCATGAAGGCTTCTGCCTGTGGGACAGCAAGGTGACGGACTACAAGGC
GCCGAACACGCCCTGTGGCAAAGATCTGCTCGCGCCGCTTGTCGAAGCCTTCCGCGCCGAAGGGCTCAAGATCGGCTTCT
ACTATTCGCTGCTTGACTGGCACCATCCCGATTTCCCGATCGACGTTCACCATCCGCTGCGCAACCATCCCGACGCCAAG
GCCCTGAATGCCGGCCGTAACATCGCCAACTACGCGGCCTATATGCGCGAACAGGTGCGCGAGCTTCTGACCGGCTTCGG
CCGCATCGACATCATCTGGTTCGATTTCAGCTATCCCGGGCGCGAATATCGCGGCCTGCCCGGCAAGGGGCGCGCCGATT
GGGAGAGCGAGCGGCTGGTCGAGCTGGTGCGCGACCTGCAGCCCGGCATCATCGTTAACAACCGCCTCGATCTGCCGCCC
GGCAGCCTGCCCGACGTAACGACGCCGGAGCAATATACGCCGCGCGTGGCCCCCGCCATCACCAGCCAGGGGGTACTCTG
GGAAGCCTGCCATACCTTCAGCGGCTCCTGGGGTTATCACCGCGACGAAGATACCTGGAAAAGCCCGGAACAGATCATCC
AGCTGTTGATCGATTCCGTCGCACTCGGCGGCAACCTGCTGATGAATGTCGGCCCGACCGGCCGGGGCACGCTCGATGCG
CGCGCCATCAGCGCGCTCGAGGTCTATCAGAACTGGATGGCCGTCAACGGACGTTCCATCTATGGGGCAGGGCCATCCCG
CTATCCGGTGCCGGCCGGCTGCCGCTATACCCAGCGCGGCAACCGCCTTTATCTGCATGTCTACAATTGGCCTTACCGCC
ACATCCACATCGAAGGTCTCGCCGACAGGATCTCTTATGCGCAATTCCTGCACGACGCCAGCGAGGTGCACTGGCTGAGC
CATGCCAAAGATGTGGATTCCAATATCGGCGTGACGGTGCCGGAAGGCATGATCACGCTCGAACTGCCGGTCCGGCGCCC
GGACGTTACCGTGCCGGTGATCGAGATCGTCCTGAAGGCGTGA

Upstream 100 bases:

>100_bases
ATCACGAATTTCGACTTGACAGACATCGGATCAGGCGAGATGATCATTCACCGAACCGGTTCGATATGATGTTGAGCCGG
AAAACAGGGAGGAGAAACCT

Downstream 100 bases:

>100_bases
GCTCGATCGCACTCGCGTGTCCTTTGCGTTCATGGAGGGAGGAGAAACCCATGAAGGTTCTGAAGAAAACGCTTTTGCTT
GCCGCTATAGGCAGCAGTCT

Product: putative alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Alpha-L-Fucosidase Protein; Exported Alpha-L-Fucosidase Protein; Alpha-1 3/4-Fucosidase; Glycoside Hydrolase Family Alpha-L-Fucosidase; Lipoprotein; Exporte Hydrolase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase-Like Protein; Ig Domain-Containing; Twin-Arginine Translocation Pathway Signal; Alpha-L-Fucosidase Superfamily; Fucosidase; Tat Pathway Signal Sequence Domain Protein; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; Coagulation Factor 5/8 Type Domain-Containing Protein; DS Domain-Containing Protein; Glycoside Hydrolase

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTSSERQPENPASGGAEKHAWFSQDRLGMFIHWGLYALGARHEWLKNREELTDEHYQRYFDNFDPDLYDPKEWARRARLA
GMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLAPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPDAK
ALNAGRNIANYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLVELVRDLQPGIIVNNRLDLPP
GSLPDVTTPEQYTPRVAPAITSQGVLWEACHTFSGSWGYHRDEDTWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTLDA
RAISALEVYQNWMAVNGRSIYGAGPSRYPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRISYAQFLHDASEVHWLS
HAKDVDSNIGVTVPEGMITLELPVRRPDVTVPVIEIVLKA

Sequences:

>Translated_440_residues
MTSSERQPENPASGGAEKHAWFSQDRLGMFIHWGLYALGARHEWLKNREELTDEHYQRYFDNFDPDLYDPKEWARRARLA
GMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLAPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPDAK
ALNAGRNIANYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLVELVRDLQPGIIVNNRLDLPP
GSLPDVTTPEQYTPRVAPAITSQGVLWEACHTFSGSWGYHRDEDTWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTLDA
RAISALEVYQNWMAVNGRSIYGAGPSRYPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRISYAQFLHDASEVHWLS
HAKDVDSNIGVTVPEGMITLELPVRRPDVTVPVIEIVLKA
>Mature_439_residues
TSSERQPENPASGGAEKHAWFSQDRLGMFIHWGLYALGARHEWLKNREELTDEHYQRYFDNFDPDLYDPKEWARRARLAG
MKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLAPLVEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPDAKA
LNAGRNIANYAAYMREQVRELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLVELVRDLQPGIIVNNRLDLPPG
SLPDVTTPEQYTPRVAPAITSQGVLWEACHTFSGSWGYHRDEDTWKSPEQIIQLLIDSVALGGNLLMNVGPTGRGTLDAR
AISALEVYQNWMAVNGRSIYGAGPSRYPVPAGCRYTQRGNRLYLHVYNWPYRHIHIEGLADRISYAQFLHDASEVHWLSH
AKDVDSNIGVTVPEGMITLELPVRRPDVTVPVIEIVLKA

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI119360348, Length=439, Percent_Identity=26.1958997722096, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI40068512, Length=440, Percent_Identity=26.5909090909091, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71997700, Length=350, Percent_Identity=24, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24662717, Length=388, Percent_Identity=26.0309278350515, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78706642, Length=388, Percent_Identity=26.0309278350515, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 50181; Mature: 50050

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSERQPENPASGGAEKHAWFSQDRLGMFIHWGLYALGARHEWLKNREELTDEHYQRYF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DNFDPDLYDPKEWARRARLAGMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLAPL
HCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHH
VEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPDAKALNAGRNIANYAAYMREQVR
HHHHHHCCEEEEEEEEEHHCCCCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHH
ELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLVELVRDLQPGIIVNNRLDLPP
HHHHCCCCEEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCC
GSLPDVTTPEQYTPRVAPAITSQGVLWEACHTFSGSWGYHRDEDTWKSPEQIIQLLIDSV
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ALGGNLLMNVGPTGRGTLDARAISALEVYQNWMAVNGRSIYGAGPSRYPVPAGCRYTQRG
HCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCC
NRLYLHVYNWPYRHIHIEGLADRISYAQFLHDASEVHWLSHAKDVDSNIGVTVPEGMITL
CEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
ELPVRRPDVTVPVIEIVLKA
EECCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TSSERQPENPASGGAEKHAWFSQDRLGMFIHWGLYALGARHEWLKNREELTDEHYQRYF
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DNFDPDLYDPKEWARRARLAGMKYVVVTTKHHEGFCLWDSKVTDYKAPNTPCGKDLLAPL
HCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHH
VEAFRAEGLKIGFYYSLLDWHHPDFPIDVHHPLRNHPDAKALNAGRNIANYAAYMREQVR
HHHHHHCCEEEEEEEEEHHCCCCCCCEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHH
ELLTGFGRIDIIWFDFSYPGREYRGLPGKGRADWESERLVELVRDLQPGIIVNNRLDLPP
HHHHCCCCEEEEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCC
GSLPDVTTPEQYTPRVAPAITSQGVLWEACHTFSGSWGYHRDEDTWKSPEQIIQLLIDSV
CCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ALGGNLLMNVGPTGRGTLDARAISALEVYQNWMAVNGRSIYGAGPSRYPVPAGCRYTQRG
HCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEECCC
NRLYLHVYNWPYRHIHIEGLADRISYAQFLHDASEVHWLSHAKDVDSNIGVTVPEGMITL
CEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
ELPVRRPDVTVPVIEIVLKA
EECCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA