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The map label for this gene is glxA [H]

Identifier: 116249200

GI number: 116249200

Start: 581505

End: 582515

Strand: Direct

Name: glxA [H]

Synonym: pRL120536

Alternate gene names: 116249200

Gene position: 581505-582515 (Clockwise)

Preceding gene: 116249199

Following gene: 116249203

Centisome position: 66.84

GC content: 60.63

Gene sequence:

>1011_bases
ATGCGACCCGAGCAGCATCGACGGGCAGATGACGCCGCGAAGTCGGCTGGTCGGCTCAAGGTAGGCTTCGTTCTGGCGCG
ATCGTTCACGCTGTCCGCTTTCGCGCTCTTCGTGGACACACTGCGGCTTGCCAGCGACGAGCAGGATCGTTCCGGAAGGG
TCCTTGCCGACTGGCAGGTGATTGGCAGCACGCGGCACCTGATCACCGCGAGTTGCGGTGTCCAGGTCGCTCCGACGTCC
GATTTCGTCGATCCGTCGAAGTTCGATTACATCGTGGTCGTCGGCGGCCTTCTGACGGTGGAGAACCCTGTCGACCAGGA
GACCATCGCTTTTCTCAAGCAGGCGGACGCCAAGAAGGTGCCGCTGATCGGCGTGTGCACGGGGTCGTTCATTCTTGCTG
CGGCAGGCCTGATGAACCGGCACGAATGCTGTGTGAGCTGGCTGCATTACAAGGAGTTTCGGGAGCGGTTTCCTGACCTC
AGCGTTCGTTCCGACCGGCTCTTCAATCTCGATCGCCAGCGCGGATCCTGCGCAGGCGGCAGCAGTTCCGCCGACATGGC
GGCATTGCTGGTCAGGAAATGTATCAGCCGCGACGCCGAACGAAACGCGCTGGAGGTGCTTCAGATCGAAAAGGCCCGGA
CTTCAGCGGACATACAGCCCCGGCGTCCGCTCTACGACGACTATGACGACGCCCGCGTCAAGGCGGCAATGATTACGATG
GAACAGTTCGTCGATGGCAGCATGTCTATACAGAAGCTTGCCGCCACGGTTGGCCTGTCACGGCGCCAACTGGAGAGGAT
TTTCATCGACAAGACGGGGATGTCTCCTGCCAAGGCCTATAATCGTGTTCGCATGGAGCGGGCGAAATCGATCCTTGCCC
AGTCGAAGGCGCCGTTGATTGAGATCGCGCTGGATGTCGGCTTTGAAAACGCCTCGCAGTTCACGCGAACGTTCAAGCGC
ACATTCGGGCAAACGCCATCGCAGCATCGTGCCGCTTCGAGAGCGCACTGA

Upstream 100 bases:

>100_bases
GTTGACGATCGGGATCCGCTAGCGCATGGCTTTCAGATCCGATGAGCGCGTTTCGTCTGAAAAGACGGGCGGCGCGGTAA
GAGGCGGCAAGGAGATGACT

Downstream 100 bases:

>100_bases
GCCCGCAATCTCGCAACATTTAAGTAAGTCCCTGTTATGCCGGCGTTCAGCGCTCGATGACCAGATCGCTGAGCGGCTTG
GAGCAACAGGGCAGGAAGAA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRPEQHRRADDAAKSAGRLKVGFVLARSFTLSAFALFVDTLRLASDEQDRSGRVLADWQVIGSTRHLITASCGVQVAPTS
DFVDPSKFDYIVVVGGLLTVENPVDQETIAFLKQADAKKVPLIGVCTGSFILAAAGLMNRHECCVSWLHYKEFRERFPDL
SVRSDRLFNLDRQRGSCAGGSSSADMAALLVRKCISRDAERNALEVLQIEKARTSADIQPRRPLYDDYDDARVKAAMITM
EQFVDGSMSIQKLAATVGLSRRQLERIFIDKTGMSPAKAYNRVRMERAKSILAQSKAPLIEIALDVGFENASQFTRTFKR
TFGQTPSQHRAASRAH

Sequences:

>Translated_336_residues
MRPEQHRRADDAAKSAGRLKVGFVLARSFTLSAFALFVDTLRLASDEQDRSGRVLADWQVIGSTRHLITASCGVQVAPTS
DFVDPSKFDYIVVVGGLLTVENPVDQETIAFLKQADAKKVPLIGVCTGSFILAAAGLMNRHECCVSWLHYKEFRERFPDL
SVRSDRLFNLDRQRGSCAGGSSSADMAALLVRKCISRDAERNALEVLQIEKARTSADIQPRRPLYDDYDDARVKAAMITM
EQFVDGSMSIQKLAATVGLSRRQLERIFIDKTGMSPAKAYNRVRMERAKSILAQSKAPLIEIALDVGFENASQFTRTFKR
TFGQTPSQHRAASRAH
>Mature_336_residues
MRPEQHRRADDAAKSAGRLKVGFVLARSFTLSAFALFVDTLRLASDEQDRSGRVLADWQVIGSTRHLITASCGVQVAPTS
DFVDPSKFDYIVVVGGLLTVENPVDQETIAFLKQADAKKVPLIGVCTGSFILAAAGLMNRHECCVSWLHYKEFRERFPDL
SVRSDRLFNLDRQRGSCAGGSSSADMAALLVRKCISRDAERNALEVLQIEKARTSADIQPRRPLYDDYDDARVKAAMITM
EQFVDGSMSIQKLAATVGLSRRQLERIFIDKTGMSPAKAYNRVRMERAKSILAQSKAPLIEIALDVGFENASQFTRTFKR
TFGQTPSQHRAASRAH

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=98, Percent_Identity=31.6326530612245, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37304; Mature: 37304

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPEQHRRADDAAKSAGRLKVGFVLARSFTLSAFALFVDTLRLASDEQDRSGRVLADWQV
CCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
IGSTRHLITASCGVQVAPTSDFVDPSKFDYIVVVGGLLTVENPVDQETIAFLKQADAKKV
CCCCCCEEEEECCEEECCCCCCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHCCCCCC
PLIGVCTGSFILAAAGLMNRHECCVSWLHYKEFRERFPDLSVRSDRLFNLDRQRGSCAGG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCC
SSSADMAALLVRKCISRDAERNALEVLQIEKARTSADIQPRRPLYDDYDDARVKAAMITM
CCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
EQFVDGSMSIQKLAATVGLSRRQLERIFIDKTGMSPAKAYNRVRMERAKSILAQSKAPLI
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
EIALDVGFENASQFTRTFKRTFGQTPSQHRAASRAH
EEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MRPEQHRRADDAAKSAGRLKVGFVLARSFTLSAFALFVDTLRLASDEQDRSGRVLADWQV
CCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
IGSTRHLITASCGVQVAPTSDFVDPSKFDYIVVVGGLLTVENPVDQETIAFLKQADAKKV
CCCCCCEEEEECCEEECCCCCCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHCCCCCC
PLIGVCTGSFILAAAGLMNRHECCVSWLHYKEFRERFPDLSVRSDRLFNLDRQRGSCAGG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCC
SSSADMAALLVRKCISRDAERNALEVLQIEKARTSADIQPRRPLYDDYDDARVKAAMITM
CCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
EQFVDGSMSIQKLAATVGLSRRQLERIFIDKTGMSPAKAYNRVRMERAKSILAQSKAPLI
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
EIALDVGFENASQFTRTFKRTFGQTPSQHRAASRAH
EEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]