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The map label for this gene is msmR [H]

Identifier: 116249113

GI number: 116249113

Start: 482804

End: 483715

Strand: Reverse

Name: msmR [H]

Synonym: pRL120448

Alternate gene names: 116249113

Gene position: 483715-482804 (Counterclockwise)

Preceding gene: 116249115

Following gene: 116249112

Centisome position: 55.6

GC content: 57.46

Gene sequence:

>912_bases
GTGGTCCAAGTCCTCCCCCTCCGCCAGCAATCTTCCACCGGAAACTCGACCGACGGGTTCGGGTGCTCGTTGAAGCAGTT
GTCGATCAACCAAAGCCTTCCTGGTTCAGACATCGATATCTTTCGTAAGGCGACAGTCAACACTGAACTCGATCAGGTCA
TGACACCGGCAAGCGATCGAGGGTTCGTCGTGGGGGTTTCCTCGCTCGGCGGCCACACGCGACGCATCTTCCACGAACAT
CGTGCGACAACCCACGACTTTACCGAGAACTCGATCTATATTCGCGATCTCTCGCACGCCTACAAGGCGGATCTCCGCGG
TCCTTTCGATTTCGTGTTGTTTGAGATTTCGCCAGCCTCCCTCGGCAAAATTGCCGATGATGCTGAAATGCCCGGCATAA
CGTCGCTGTCAGTTGAAACAGCATCAAAAGATATTGTGCTTGCCAATCTCGCTCGGGCGCTGATCCCGGCGCTCGAAAAG
CCAGACGAAGCCAACGCGCTTTTCGTCGAACAAATGACGACCGCCATCGGCACCTACCTGGTCCAGCGCTACGGCGGCCG
GCCAATGGTAGGCTCCGATAGGTCGGGTAGCCTTTCGCGGGCGCAGGAGGATCTGGCGAAAAGCCTGCTTCTCGAAAACC
TTGATGGCAACGTGTCGATTTCCGACGTCGCCCAGGTCTGCAACCTGTCACGTGGCTATTTCATTCGCGCTTTTCGTCAA
ACGACCGGTATGACGCCCTATCAATGGGTCCTTCGTGAGCGAATAAGCCGTGCCCGCGACATCTTGCGGACCTCAAATAC
TCCTCTCGCCGAAGTGGCCATCGCCTGCGGCTTCGCGGACCAAAGCCATTTCACGCGCGTCTTTGCGGGTATCGTCGGCA
CCACGCCTGGCAATTGGCGGCGTAACGCGTAG

Upstream 100 bases:

>100_bases
GGCCGATTTAATAAATTGTCGTGAGGCAAGCTTACCGTGGGAAAGCGACCAAAGCCGGCAGGTCCCCTGTTCGAGTGTCT
AGAAATGAAAGAACTGCGTC

Downstream 100 bases:

>100_bases
TCCACACGAGCCCTTGGTAAGGGTCTGCCCAATTGAGGGTCTTGAACCGATTCGAACCTGAGACACACCAAATCCCACAG
TTCCATCCGAGGCGTCGCTA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MVQVLPLRQQSSTGNSTDGFGCSLKQLSINQSLPGSDIDIFRKATVNTELDQVMTPASDRGFVVGVSSLGGHTRRIFHEH
RATTHDFTENSIYIRDLSHAYKADLRGPFDFVLFEISPASLGKIADDAEMPGITSLSVETASKDIVLANLARALIPALEK
PDEANALFVEQMTTAIGTYLVQRYGGRPMVGSDRSGSLSRAQEDLAKSLLLENLDGNVSISDVAQVCNLSRGYFIRAFRQ
TTGMTPYQWVLRERISRARDILRTSNTPLAEVAIACGFADQSHFTRVFAGIVGTTPGNWRRNA

Sequences:

>Translated_303_residues
MVQVLPLRQQSSTGNSTDGFGCSLKQLSINQSLPGSDIDIFRKATVNTELDQVMTPASDRGFVVGVSSLGGHTRRIFHEH
RATTHDFTENSIYIRDLSHAYKADLRGPFDFVLFEISPASLGKIADDAEMPGITSLSVETASKDIVLANLARALIPALEK
PDEANALFVEQMTTAIGTYLVQRYGGRPMVGSDRSGSLSRAQEDLAKSLLLENLDGNVSISDVAQVCNLSRGYFIRAFRQ
TTGMTPYQWVLRERISRARDILRTSNTPLAEVAIACGFADQSHFTRVFAGIVGTTPGNWRRNA
>Mature_303_residues
MVQVLPLRQQSSTGNSTDGFGCSLKQLSINQSLPGSDIDIFRKATVNTELDQVMTPASDRGFVVGVSSLGGHTRRIFHEH
RATTHDFTENSIYIRDLSHAYKADLRGPFDFVLFEISPASLGKIADDAEMPGITSLSVETASKDIVLANLARALIPALEK
PDEANALFVEQMTTAIGTYLVQRYGGRPMVGSDRSGSLSRAQEDLAKSLLLENLDGNVSISDVAQVCNLSRGYFIRAFRQ
TTGMTPYQWVLRERISRARDILRTSNTPLAEVAIACGFADQSHFTRVFAGIVGTTPGNWRRNA

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33143; Mature: 33143

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVLPLRQQSSTGNSTDGFGCSLKQLSINQSLPGSDIDIFRKATVNTELDQVMTPASDR
CEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCC
GFVVGVSSLGGHTRRIFHEHRATTHDFTENSIYIRDLSHAYKADLRGPFDFVLFEISPAS
CEEEEEHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECHHH
LGKIADDAEMPGITSLSVETASKDIVLANLARALIPALEKPDEANALFVEQMTTAIGTYL
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VQRYGGRPMVGSDRSGSLSRAQEDLAKSLLLENLDGNVSISDVAQVCNLSRGYFIRAFRQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHH
TTGMTPYQWVLRERISRARDILRTSNTPLAEVAIACGFADQSHFTRVFAGIVGTTPGNWR
HCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
RNA
CCC
>Mature Secondary Structure
MVQVLPLRQQSSTGNSTDGFGCSLKQLSINQSLPGSDIDIFRKATVNTELDQVMTPASDR
CEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCC
GFVVGVSSLGGHTRRIFHEHRATTHDFTENSIYIRDLSHAYKADLRGPFDFVLFEISPAS
CEEEEEHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECHHH
LGKIADDAEMPGITSLSVETASKDIVLANLARALIPALEKPDEANALFVEQMTTAIGTYL
HCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VQRYGGRPMVGSDRSGSLSRAQEDLAKSLLLENLDGNVSISDVAQVCNLSRGYFIRAFRQ
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHH
TTGMTPYQWVLRERISRARDILRTSNTPLAEVAIACGFADQSHFTRVFAGIVGTTPGNWR
HCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
RNA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]