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The map label for this gene is rbsC [H]

Identifier: 116249056

GI number: 116249056

Start: 422258

End: 423322

Strand: Reverse

Name: rbsC [H]

Synonym: pRL120390

Alternate gene names: 116249056

Gene position: 423322-422258 (Counterclockwise)

Preceding gene: 116249057

Following gene: 116249055

Centisome position: 48.66

GC content: 61.13

Gene sequence:

>1065_bases
ATGATGGCGGCTACATCAACCACTCTTGCGCCGAAGGGCGCCAACGGCTCGGCACTTCTGACACTGATGAAGCTCAGGAC
GTTCATCGCGCTGTTCGCTGTCATCATCTTCTTTGCGATCTTCGCCCCGAACTTCACCTCGACGGCGAACATGATCCTGA
TGTCGAAGCATGTGGCGCTGAACGCCTTCCTGGTGATGGGCATGACCTTCGTCATCATCACCGGCGGCATTGATCTCTCG
GTCGGATCGATCGTCGGGCTTTGCGGCATGGTCGCCGGCGGCCTGATCCTTTACGGCATCGAATTGCCGATCGGCTACAC
CATCTTTTTCAACCTCTTCGAGATCGTGCTGATCACCTTGTCGATCGGCCTGCTCATCGGTCTGATCAACGGCCTGCTGA
TCACCAAGCTCAACGTCGCGCCCTTCATCGCCACGCTCGGCACGCTCTATATCGCCCGCGGTCTCGCTTTGCTGTCATCG
GACGGCCAGACCTTTCCGAACCTTGTCGGCCGGCCTGAATATGCCACGACCGGCTTCGATTTCTTCGGCGCAGGACGCAT
TCTCGGCCTGCCGGTGTCGATCTGGATCCTGATCGTGCTTGCGCTGCTGGCGGCCTATGTCGCCCGCTCGACGCCGATCG
GCCGTCATATCTTCGCCGTCGGCGGCAATGAGCGTGCCGCGCGCATGTCCGGTATCCGGGTCGATGTCGTGAAGATCTTC
GTCTACATGTTCTCCGGACTTTGCGCGGCAATCGTCGGCGTCGTCATCTCCTCCGAGCTGATGGCAGCCCATCCGGCAAC
CGGCGAAAGCTTCGAACTCAATGCGATTGCCGCAGCCGTGCTTGGCGGCACCTCGATGTCGGGCGGCCGCGGCACGATCG
GCGGCACGATCATCGGCGCCTTCGTCATCGGCATCCTCTCCGACGGGTTGGTGATGATGGGCGTCTCCTCCTTCTGGCAG
ATGGTCATCAAGGGCCTGGTCATCATCATCGCCGTCGTGGTCGACCAGGCGCAGCGCCGCCTGCAGCAGCGCGTCACCCT
CATGCAGATGGCAAAGGCAGGTTGA

Upstream 100 bases:

>100_bases
ACGGCCAGCTGGTCGCCGTCTTCGACCGCAACGAGGCGACGGAAGAAGCCATAATCGCGGCTTCGGCCAAGGGACACGGA
CATCAAGGGAAACTCGCGTC

Downstream 100 bases:

>100_bases
TATGACGGAATTGAAAGGGGCTTTGATCGGTTGCGGCTTCTTTGCGATCAACCAGATGCATGCCTGGAACGACGTTCGGG
GCGCCGGCATCGTCGCGATC

Product: putative permease component of ABC transporter

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MMAATSTTLAPKGANGSALLTLMKLRTFIALFAVIIFFAIFAPNFTSTANMILMSKHVALNAFLVMGMTFVIITGGIDLS
VGSIVGLCGMVAGGLILYGIELPIGYTIFFNLFEIVLITLSIGLLIGLINGLLITKLNVAPFIATLGTLYIARGLALLSS
DGQTFPNLVGRPEYATTGFDFFGAGRILGLPVSIWILIVLALLAAYVARSTPIGRHIFAVGGNERAARMSGIRVDVVKIF
VYMFSGLCAAIVGVVISSELMAAHPATGESFELNAIAAAVLGGTSMSGGRGTIGGTIIGAFVIGILSDGLVMMGVSSFWQ
MVIKGLVIIIAVVVDQAQRRLQQRVTLMQMAKAG

Sequences:

>Translated_354_residues
MMAATSTTLAPKGANGSALLTLMKLRTFIALFAVIIFFAIFAPNFTSTANMILMSKHVALNAFLVMGMTFVIITGGIDLS
VGSIVGLCGMVAGGLILYGIELPIGYTIFFNLFEIVLITLSIGLLIGLINGLLITKLNVAPFIATLGTLYIARGLALLSS
DGQTFPNLVGRPEYATTGFDFFGAGRILGLPVSIWILIVLALLAAYVARSTPIGRHIFAVGGNERAARMSGIRVDVVKIF
VYMFSGLCAAIVGVVISSELMAAHPATGESFELNAIAAAVLGGTSMSGGRGTIGGTIIGAFVIGILSDGLVMMGVSSFWQ
MVIKGLVIIIAVVVDQAQRRLQQRVTLMQMAKAG
>Mature_354_residues
MMAATSTTLAPKGANGSALLTLMKLRTFIALFAVIIFFAIFAPNFTSTANMILMSKHVALNAFLVMGMTFVIITGGIDLS
VGSIVGLCGMVAGGLILYGIELPIGYTIFFNLFEIVLITLSIGLLIGLINGLLITKLNVAPFIATLGTLYIARGLALLSS
DGQTFPNLVGRPEYATTGFDFFGAGRILGLPVSIWILIVLALLAAYVARSTPIGRHIFAVGGNERAARMSGIRVDVVKIF
VYMFSGLCAAIVGVVISSELMAAHPATGESFELNAIAAAVLGGTSMSGGRGTIGGTIIGAFVIGILSDGLVMMGVSSFWQ
MVIKGLVIIIAVVVDQAQRRLQQRVTLMQMAKAG

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=318, Percent_Identity=41.5094339622642, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788896, Length=338, Percent_Identity=34.3195266272189, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790524, Length=316, Percent_Identity=35.126582278481, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI145693152, Length=316, Percent_Identity=33.8607594936709, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789992, Length=390, Percent_Identity=31.025641025641, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI145693214, Length=254, Percent_Identity=35.4330708661417, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787793, Length=298, Percent_Identity=33.2214765100671, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082395, Length=323, Percent_Identity=30.6501547987616, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788471, Length=345, Percent_Identity=33.6231884057971, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787794, Length=304, Percent_Identity=33.2236842105263, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 37032; Mature: 37032

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAATSTTLAPKGANGSALLTLMKLRTFIALFAVIIFFAIFAPNFTSTANMILMSKHVAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NAFLVMGMTFVIITGGIDLSVGSIVGLCGMVAGGLILYGIELPIGYTIFFNLFEIVLITL
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHH
SIGLLIGLINGLLITKLNVAPFIATLGTLYIARGLALLSSDGQTFPNLVGRPEYATTGFD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCC
FFGAGRILGLPVSIWILIVLALLAAYVARSTPIGRHIFAVGGNERAARMSGIRVDVVKIF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCHHHHHHHH
VYMFSGLCAAIVGVVISSELMAAHPATGESFELNAIAAAVLGGTSMSGGRGTIGGTIIGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FVIGILSDGLVMMGVSSFWQMVIKGLVIIIAVVVDQAQRRLQQRVTLMQMAKAG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMAATSTTLAPKGANGSALLTLMKLRTFIALFAVIIFFAIFAPNFTSTANMILMSKHVAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NAFLVMGMTFVIITGGIDLSVGSIVGLCGMVAGGLILYGIELPIGYTIFFNLFEIVLITL
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHH
SIGLLIGLINGLLITKLNVAPFIATLGTLYIARGLALLSSDGQTFPNLVGRPEYATTGFD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCC
FFGAGRILGLPVSIWILIVLALLAAYVARSTPIGRHIFAVGGNERAARMSGIRVDVVKIF
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCCCHHHHHHHH
VYMFSGLCAAIVGVVISSELMAAHPATGESFELNAIAAAVLGGTSMSGGRGTIGGTIIGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FVIGILSDGLVMMGVSSFWQMVIKGLVIIIAVVVDQAQRRLQQRVTLMQMAKAG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]