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The map label for this gene is xylR [H]

Identifier: 116249023

GI number: 116249023

Start: 382973

End: 384253

Strand: Direct

Name: xylR [H]

Synonym: pRL120354

Alternate gene names: 116249023

Gene position: 382973-384253 (Clockwise)

Preceding gene: 116249022

Following gene: 116249024

Centisome position: 44.02

GC content: 61.98

Gene sequence:

>1281_bases
ATGAGGAGCGGTTCAAGCTATGCGCAAGGAAGGATTTCAAGCATGAACCAGACACTCGGCGCCAGACTGTCCCCGGATCT
GACCGGCGCCAATGTCGAAGATGCAGGTGAGCACAATAGGGCCGTCGTCCTGCGCTGCATTCATCGCCAGGCGCCGATTT
CGCGCGCTGAAATTGCCAGGCGGACGGGTTTTACCAAACCGGCAATCGCCCGGATCGTCGATCGCCTGCTGGACGAGGGG
CTGATCATGGAAGCCCGCCGGCGGCATGGGTTGAGAGGCCAGCCGGCAATCGAACTCGAAATCAATCCGGATGCCTGCTT
TGCCATCGGCATCAACATCGATCGCGACCATCTGACGATCCTGGCCGTCGATGCCGTCGGCAATGTCCGCGCCCGCGTGC
ACCATGAGAAACGCTTCATCCTGCCGGCGGAATTCCTGCAGCTCACGGCCGATGCGATTTCGCATTTCCAACGCAGCCGG
CTCATCGACGACGCGCGCCTCGCCGGTATCGGTCTGGCGATGCCGGATTGGCTTGGCGAGATTTCGCTCCTCGGCAAGCC
CGAGGCTTATCAGGAATGGACGGCATTCGATGTGCGCGCCGCACTGGAGAACCTGACGCAGCATCCCGTCTTCATCGAAA
ACGAAGCCAATGCCGCAGCCCTTGCCGAACTCGATTATGGACTGGGTGCTGAAAGCAGCAGCTTCTTCTACATCGCCATC
AACCCATGCCCGGGCGGCGGCCTCGTGCTCGACGGCAACGGTCATCGTGGCGCCATGGGCCTCAGCGGCGAAATCGGCTG
GCTGCCGATCGCCGACGGCCGGGACGGGACGGCCCATAAGGTCCAGCTTCTCGGCGAGATATTCTCGCTGTTCTTCCTCT
ATGATTTCCTTGCGCAACACGGCGTCGAGGTGAGTGTTCCCCACGATCTCCTGACGCTGGATGCGCATGGCAGGCGCCTC
GTTTCGCAGTGGCTGAAGGAAATGAGCGCGCATCTGGCCGTCGCCGTCAAGCATATTGGCATGGTCGTCGACCCCGACGC
CGTCCTCGTCGGCGGCCGATTGCCGATCCGCATCGTCGACGAATTGCTGCGCTATGTGCACGAGCATCTCGATGCCGAGG
ACACCAACCTTCCCTCGCTTCATCGCGCCTCGCTCGGAGAGGATGCCTCGGCCATGGGGGCGGCGGTTATGCCGATGGCA
GCAGCCCTCATGCTCGCATCGGCCGACGCGGCTCAACGCACACGTTCGCCACTCAAGAACATGGATCGCCTGAACAGTTG
A

Upstream 100 bases:

>100_bases
TTGCCGCCGCCTGCCTGATCGCGGTCGTTCCGGCGATCGTCGCCTTCCTGTCGCTCCAGCGGCTGATCCTCGGTGCGATG
ACCAGCGGCGCGGTCAAGGG

Downstream 100 bases:

>100_bases
AACGGCTGGCAAGGCCCACGGATTTTGGTGAAGAACGGGATTTTGGTGAAGATCGGAGGATTTTGGTGAAGATCGGCTTT
TACACTTCGACATTCAACGA

Product: ROK family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MRSGSSYAQGRISSMNQTLGARLSPDLTGANVEDAGEHNRAVVLRCIHRQAPISRAEIARRTGFTKPAIARIVDRLLDEG
LIMEARRRHGLRGQPAIELEINPDACFAIGINIDRDHLTILAVDAVGNVRARVHHEKRFILPAEFLQLTADAISHFQRSR
LIDDARLAGIGLAMPDWLGEISLLGKPEAYQEWTAFDVRAALENLTQHPVFIENEANAAALAELDYGLGAESSSFFYIAI
NPCPGGGLVLDGNGHRGAMGLSGEIGWLPIADGRDGTAHKVQLLGEIFSLFFLYDFLAQHGVEVSVPHDLLTLDAHGRRL
VSQWLKEMSAHLAVAVKHIGMVVDPDAVLVGGRLPIRIVDELLRYVHEHLDAEDTNLPSLHRASLGEDASAMGAAVMPMA
AALMLASADAAQRTRSPLKNMDRLNS

Sequences:

>Translated_426_residues
MRSGSSYAQGRISSMNQTLGARLSPDLTGANVEDAGEHNRAVVLRCIHRQAPISRAEIARRTGFTKPAIARIVDRLLDEG
LIMEARRRHGLRGQPAIELEINPDACFAIGINIDRDHLTILAVDAVGNVRARVHHEKRFILPAEFLQLTADAISHFQRSR
LIDDARLAGIGLAMPDWLGEISLLGKPEAYQEWTAFDVRAALENLTQHPVFIENEANAAALAELDYGLGAESSSFFYIAI
NPCPGGGLVLDGNGHRGAMGLSGEIGWLPIADGRDGTAHKVQLLGEIFSLFFLYDFLAQHGVEVSVPHDLLTLDAHGRRL
VSQWLKEMSAHLAVAVKHIGMVVDPDAVLVGGRLPIRIVDELLRYVHEHLDAEDTNLPSLHRASLGEDASAMGAAVMPMA
AALMLASADAAQRTRSPLKNMDRLNS
>Mature_426_residues
MRSGSSYAQGRISSMNQTLGARLSPDLTGANVEDAGEHNRAVVLRCIHRQAPISRAEIARRTGFTKPAIARIVDRLLDEG
LIMEARRRHGLRGQPAIELEINPDACFAIGINIDRDHLTILAVDAVGNVRARVHHEKRFILPAEFLQLTADAISHFQRSR
LIDDARLAGIGLAMPDWLGEISLLGKPEAYQEWTAFDVRAALENLTQHPVFIENEANAAALAELDYGLGAESSSFFYIAI
NPCPGGGLVLDGNGHRGAMGLSGEIGWLPIADGRDGTAHKVQLLGEIFSLFFLYDFLAQHGVEVSVPHDLLTLDAHGRRL
VSQWLKEMSAHLAVAVKHIGMVVDPDAVLVGGRLPIRIVDELLRYVHEHLDAEDTNLPSLHRASLGEDASAMGAAVMPMA
AALMLASADAAQRTRSPLKNMDRLNS

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=385, Percent_Identity=24.4155844155844, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787878, Length=242, Percent_Identity=24.3801652892562, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 46305; Mature: 46305

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGSSYAQGRISSMNQTLGARLSPDLTGANVEDAGEHNRAVVLRCIHRQAPISRAEIAR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
RTGFTKPAIARIVDRLLDEGLIMEARRRHGLRGQPAIELEINPDACFAIGINIDRDHLTI
HCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCEEE
LAVDAVGNVRARVHHEKRFILPAEFLQLTADAISHFQRSRLIDDARLAGIGLAMPDWLGE
EEEECCCCHHHHEECCCEEECHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHCC
ISLLGKPEAYQEWTAFDVRAALENLTQHPVFIENEANAAALAELDYGLGAESSSFFYIAI
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCCEEEEEE
NPCPGGGLVLDGNGHRGAMGLSGEIGWLPIADGRDGTAHKVQLLGEIFSLFFLYDFLAQH
ECCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GVEVSVPHDLLTLDAHGRRLVSQWLKEMSAHLAVAVKHIGMVVDPDAVLVGGRLPIRIVD
CCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCHHHHH
ELLRYVHEHLDAEDTNLPSLHRASLGEDASAMGAAVMPMAAALMLASADAAQRTRSPLKN
HHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MDRLNS
HHHCCC
>Mature Secondary Structure
MRSGSSYAQGRISSMNQTLGARLSPDLTGANVEDAGEHNRAVVLRCIHRQAPISRAEIAR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
RTGFTKPAIARIVDRLLDEGLIMEARRRHGLRGQPAIELEINPDACFAIGINIDRDHLTI
HCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCEEE
LAVDAVGNVRARVHHEKRFILPAEFLQLTADAISHFQRSRLIDDARLAGIGLAMPDWLGE
EEEECCCCHHHHEECCCEEECHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHCC
ISLLGKPEAYQEWTAFDVRAALENLTQHPVFIENEANAAALAELDYGLGAESSSFFYIAI
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCCCCCCEEEEEE
NPCPGGGLVLDGNGHRGAMGLSGEIGWLPIADGRDGTAHKVQLLGEIFSLFFLYDFLAQH
ECCCCCCEEECCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GVEVSVPHDLLTLDAHGRRLVSQWLKEMSAHLAVAVKHIGMVVDPDAVLVGGRLPIRIVD
CCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCHHHHH
ELLRYVHEHLDAEDTNLPSLHRASLGEDASAMGAAVMPMAAALMLASADAAQRTRSPLKN
HHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MDRLNS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]