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The map label for this gene is cobO [H]

Identifier: 114800288

GI number: 114800288

Start: 1547362

End: 1547964

Strand: Direct

Name: cobO [H]

Synonym: HNE_1513

Alternate gene names: 114800288

Gene position: 1547362-1547964 (Clockwise)

Preceding gene: 114797780

Following gene: 114798415

Centisome position: 41.76

GC content: 55.39

Gene sequence:

>603_bases
ATGAGCGAACACGACACACACACCGAAAAGATGAAGGCGCTGCAGGCTGAGCAAAAGAAGAAGACCTCTGAAGCGCGTGA
TCCGGGTCGCGGTCTCGTGCTGGTTCACACCGGAGATGGGAAGGGCAAGTCGAGTTCTGCATTCGGTGTCATCATCCGGG
CGCTCGGCTGGAAGCAGAAAGTCGGGGTCGTCCAGTTCATCAAGGGCAAATGGATCACAGGCGAAAAGCAGTTCTTTATG
GCGCTTAAGGATCAGGTGGACTGGTACACAATGGGTGATGGCTTCACCTGGGATACGCAGGACCGGGACCGCGACATTGC
AGCGGCCGAAGCGGCATTTGCCAAAGCTCGCGAGATGATGGAGCGCGGCGACTATGATCTGATTGTGCTGGATGAAATCA
ATATCGCGCTTCGCTATGATTATCTTGACGTGGGAGCCGTGATTGAGGGACTGAAGGCCCGGTCAGACCGGACAAGCGTC
ATCCTGACGGGGCGCAATGCCAAACCGGAACTCTGTGAATATGCAGACCTCGTCAGCGAAATGACCGAAGTGAAGCACCC
CTTCAAGGCCGGTATAAAGGCTCAGCGCGGAATTGATTTCTAG

Upstream 100 bases:

>100_bases
TCATCAAGGCCGCTCTCGCAACGGACGAAACCGCCGACAGCCATGCAATGACGCTGGATTTTGGAAACTTTGTTACTTTG
ATTGACTGAAAGGGCGCTGC

Downstream 100 bases:

>100_bases
CAATTGCTTTTTGCGTCATTGGCCAAAAGAGGCATTGACACACATTCGCACTTGCAACATCAACCCCATCAGATGGTGCT
CCCCTGACAGGGAGCTAAGA

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSEHDTHTEKMKALQAEQKKKTSEARDPGRGLVLVHTGDGKGKSSSAFGVIIRALGWKQKVGVVQFIKGKWITGEKQFFM
ALKDQVDWYTMGDGFTWDTQDRDRDIAAAEAAFAKAREMMERGDYDLIVLDEINIALRYDYLDVGAVIEGLKARSDRTSV
ILTGRNAKPELCEYADLVSEMTEVKHPFKAGIKAQRGIDF

Sequences:

>Translated_200_residues
MSEHDTHTEKMKALQAEQKKKTSEARDPGRGLVLVHTGDGKGKSSSAFGVIIRALGWKQKVGVVQFIKGKWITGEKQFFM
ALKDQVDWYTMGDGFTWDTQDRDRDIAAAEAAFAKAREMMERGDYDLIVLDEINIALRYDYLDVGAVIEGLKARSDRTSV
ILTGRNAKPELCEYADLVSEMTEVKHPFKAGIKAQRGIDF
>Mature_199_residues
SEHDTHTEKMKALQAEQKKKTSEARDPGRGLVLVHTGDGKGKSSSAFGVIIRALGWKQKVGVVQFIKGKWITGEKQFFMA
LKDQVDWYTMGDGFTWDTQDRDRDIAAAEAAFAKAREMMERGDYDLIVLDEINIALRYDYLDVGAVIEGLKARSDRTSVI
LTGRNAKPELCEYADLVSEMTEVKHPFKAGIKAQRGIDF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=180, Percent_Identity=43.8888888888889, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22435; Mature: 22304

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHDTHTEKMKALQAEQKKKTSEARDPGRGLVLVHTGDGKGKSSSAFGVIIRALGWKQK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHH
VGVVQFIKGKWITGEKQFFMALKDQVDWYTMGDGFTWDTQDRDRDIAAAEAAFAKAREMM
CCHHHHHCCCEECCCHHHHHHHHHCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHH
ERGDYDLIVLDEINIALRYDYLDVGAVIEGLKARSDRTSVILTGRNAKPELCEYADLVSE
HCCCCCEEEEECCCEEEEECEEHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHH
MTEVKHPFKAGIKAQRGIDF
HHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEHDTHTEKMKALQAEQKKKTSEARDPGRGLVLVHTGDGKGKSSSAFGVIIRALGWKQK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHH
VGVVQFIKGKWITGEKQFFMALKDQVDWYTMGDGFTWDTQDRDRDIAAAEAAFAKAREMM
CCHHHHHCCCEECCCHHHHHHHHHCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHH
ERGDYDLIVLDEINIALRYDYLDVGAVIEGLKARSDRTSVILTGRNAKPELCEYADLVSE
HCCCCCEEEEECCCEEEEECEEHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHH
MTEVKHPFKAGIKAQRGIDF
HHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]