Click here to switch to the map view.

The map label for this gene is selD [H]

Identifier: 114800156

GI number: 114800156

Start: 2619226

End: 2621412

Strand: Direct

Name: selD [H]

Synonym: HNE_2490

Alternate gene names: 114800156

Gene position: 2619226-2621412 (Clockwise)

Preceding gene: 114797954

Following gene: 114800408

Centisome position: 70.69

GC content: 64.43

Gene sequence:

>2187_bases
ATGCACCCTGACTGGCCCCTTTCGAGAGACCTTGTCCTCATCGGCGGCGGGCATACCCATGCGCTTGTCCTGCGCAAATG
GGGAATGAACCCTTTGCCAGGCGCGCGGGTCACGCTGATCAATCCGGGCGCGGCCAGCCCTTATACCGGCATGCTCCCCG
GCCACATTGCGGGTCACTACACGCGCGATGAACTCGATATCGATCTGGTGCGCCTGGCACGGTTTGCGGGTGCCCGGATC
GTATTCGATACCGCCTGCGGCCTGGACCTGATGGCCAAGCGGGTCCACCTCACCGGGCGCCCGCCCATCCGCTACGATGT
CGTCTCGATCGACATCGGCGCTACCGCAGAACTGCCCGGTATCGAGGGCTTCACCCAGCATGCCCATTCGGTCAAACCCC
TCGGCCTTTTTGCAAGCGCCTGGCAATCCTTTCTCGAGAAGGCGGCGATGCAGGGCAGACCCGCAGACTGCGCCGTGATC
GGCGGCGGGGTTGCGGGCGTTGAGCTTGCCCTCGCCATGGCATACCGGCTGAAAACGAGTGGCCTGGCTGAGGCCCGCAT
CACCCTGATCGAATCCGGGCCCGGCCTGCTCCAGGCCACCAGCGCCGTAACCCGACGGATCTTGATGCGCGCACTCTCGC
GTTCGGGCATAACCGTCCTTACCGGCGCGCAGGTCACGCGCATCTCCAGCGGCGCAATCGCGCTTGCAGGGCGCGAAAGC
CTGCCGGCGGATTTCATCGTCAGTGCGGCCGGGGCACGGCCCTACCCCTGGCTCGCGGAAACGGGCCTTGCGCACACAGG
CGGCTTCCTCAATGTCGGACCAGACCTGCGCACCCTGACAGACCCGGATGTTTTCGCGGCCGGAGATTGCGCCCACCTGA
CCCATGCCCCCCGTCCAAAGGCGGGCGTGTACGCCGTGCGCGCAGCGCCCATCCTGTTCGAAAACCTCAGAGCCCGCCTC
AGCGGCCAGACATTGCGGGAATTTGCGCCGCAGTCTGACTATCTGAAACTCATATCCAAAGGCGACAGGTCTGCCGTTGG
GCACAAACATTTCTTCACACTTTCCGGCCGATCCGTCTGGCGGCTGAAAGACCATATCGACAAGACATTCATGGCCCGCC
TGCATGACCTGCCCGCCATGCGCACGCCGCCCCCGCCCCGCGTGCGCGCGCTGGATGAGGAAGCAGAAACCCGGTCAGAG
CCGCTTTGCGGAGGCTGCGGGTCAAAGGTCGGCCGCCAGAATCTGATCTCTGCCCTTTCGGGCCTGCCCCCTGCCCTGCA
CGCCGATACAATCACCGGGGCGGGTGATGACGCCGCCGTGCTGCGCTCAGGGGCGCGTCTTCAGGTCATTAGCACAGATC
ATCTGCGGGCATTCGTCGACGATCCGTATCTCATGGCCCGCATTGCCGCCGTTCATGCTCTTGGCGATGTCTGTGCGATG
GGCGCTGCGCCGCAATCTGCGCTCCTCTCCCTGATCATTCCGCGCATGAGTGACCCGATGCAGAAGGCGACGGTCGCGGA
AGTGGTCGCCGCTGTAAGCGACGTACTGCGCGCCGCAGGCGCAGACCTCGTCGGCGGGCACACAAGCATGGGCCGTGAAC
TGACAATCGGGCTCACAGTCACCGGCTTGCTGGATGGCCCGGCCATTGGCCTCACAGGCGCCCGGCCAGGCGATGCGATC
CTGCTGACTAAGCCGCTCGGAACAGGCGTGATTCTCGCCGCCGAGATGCGCGGGCTTGCCCGCGGCAAGGATGTAGAACA
CGCGCTCGCCAGCATGCAGCGCCCGCTGGCCGCCGCCTCGAAAATCCTCGCCCCGGCCGCGCATGCAATGACAGACGTTA
CGGGTTTCGGACTAGCTGGGCACCTCATGAGCATTCTGGAGGCATCCGATGTGTCGGCCAGAATTGCACTGCCGGACCTA
CCTGTTCTTCCGGGTGCTGAGCAACTCTCAGCTCAGGGCATCCGCTCATCCCTATGGCAATCGAATGCGAGCCTTGAGCC
GCGTATTTCGCGTCCGGCATCGCCCATCAGTGATCTCATCTACGATCCGCAGACTGCAGGCGGGTTGCTGGCGGTTGTTC
CGTCCCAAAGTGTCACCGGCTTGCTATCGGCGTTTCAGGCGGAGGGAGAGCCAGCCTTTGTGATCGGCCGAATTGAAGAG
GGCCCGCCCCGCATCCTTGTCAACTGA

Upstream 100 bases:

>100_bases
CGCCGGGGCGCCGCCCGGGCCCGGCCAGCCACGCGCGCTGGCGCTGACAGCCACACTCCCCTAAAGATCGCAACCTTATT
GGCAAAGGCATCCGACGCAC

Downstream 100 bases:

>100_bases
TACCAGTGAGAGCGTCGCCAGCAAGGGTCAGAACTTCCTGCGCGGCGCGATCCAGCGCATCAGGACCAAACCCCTGCAGC
CGCACGCAACCGAGTTCCGG

Product: pyridine nucleotide-disulphide oxidoreductase / selenide, water dikinase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MHPDWPLSRDLVLIGGGHTHALVLRKWGMNPLPGARVTLINPGAASPYTGMLPGHIAGHYTRDELDIDLVRLARFAGARI
VFDTACGLDLMAKRVHLTGRPPIRYDVVSIDIGATAELPGIEGFTQHAHSVKPLGLFASAWQSFLEKAAMQGRPADCAVI
GGGVAGVELALAMAYRLKTSGLAEARITLIESGPGLLQATSAVTRRILMRALSRSGITVLTGAQVTRISSGAIALAGRES
LPADFIVSAAGARPYPWLAETGLAHTGGFLNVGPDLRTLTDPDVFAAGDCAHLTHAPRPKAGVYAVRAAPILFENLRARL
SGQTLREFAPQSDYLKLISKGDRSAVGHKHFFTLSGRSVWRLKDHIDKTFMARLHDLPAMRTPPPPRVRALDEEAETRSE
PLCGGCGSKVGRQNLISALSGLPPALHADTITGAGDDAAVLRSGARLQVISTDHLRAFVDDPYLMARIAAVHALGDVCAM
GAAPQSALLSLIIPRMSDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSMGRELTIGLTVTGLLDGPAIGLTGARPGDAI
LLTKPLGTGVILAAEMRGLARGKDVEHALASMQRPLAAASKILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDL
PVLPGAEQLSAQGIRSSLWQSNASLEPRISRPASPISDLIYDPQTAGGLLAVVPSQSVTGLLSAFQAEGEPAFVIGRIEE
GPPRILVN

Sequences:

>Translated_728_residues
MHPDWPLSRDLVLIGGGHTHALVLRKWGMNPLPGARVTLINPGAASPYTGMLPGHIAGHYTRDELDIDLVRLARFAGARI
VFDTACGLDLMAKRVHLTGRPPIRYDVVSIDIGATAELPGIEGFTQHAHSVKPLGLFASAWQSFLEKAAMQGRPADCAVI
GGGVAGVELALAMAYRLKTSGLAEARITLIESGPGLLQATSAVTRRILMRALSRSGITVLTGAQVTRISSGAIALAGRES
LPADFIVSAAGARPYPWLAETGLAHTGGFLNVGPDLRTLTDPDVFAAGDCAHLTHAPRPKAGVYAVRAAPILFENLRARL
SGQTLREFAPQSDYLKLISKGDRSAVGHKHFFTLSGRSVWRLKDHIDKTFMARLHDLPAMRTPPPPRVRALDEEAETRSE
PLCGGCGSKVGRQNLISALSGLPPALHADTITGAGDDAAVLRSGARLQVISTDHLRAFVDDPYLMARIAAVHALGDVCAM
GAAPQSALLSLIIPRMSDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSMGRELTIGLTVTGLLDGPAIGLTGARPGDAI
LLTKPLGTGVILAAEMRGLARGKDVEHALASMQRPLAAASKILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDL
PVLPGAEQLSAQGIRSSLWQSNASLEPRISRPASPISDLIYDPQTAGGLLAVVPSQSVTGLLSAFQAEGEPAFVIGRIEE
GPPRILVN
>Mature_728_residues
MHPDWPLSRDLVLIGGGHTHALVLRKWGMNPLPGARVTLINPGAASPYTGMLPGHIAGHYTRDELDIDLVRLARFAGARI
VFDTACGLDLMAKRVHLTGRPPIRYDVVSIDIGATAELPGIEGFTQHAHSVKPLGLFASAWQSFLEKAAMQGRPADCAVI
GGGVAGVELALAMAYRLKTSGLAEARITLIESGPGLLQATSAVTRRILMRALSRSGITVLTGAQVTRISSGAIALAGRES
LPADFIVSAAGARPYPWLAETGLAHTGGFLNVGPDLRTLTDPDVFAAGDCAHLTHAPRPKAGVYAVRAAPILFENLRARL
SGQTLREFAPQSDYLKLISKGDRSAVGHKHFFTLSGRSVWRLKDHIDKTFMARLHDLPAMRTPPPPRVRALDEEAETRSE
PLCGGCGSKVGRQNLISALSGLPPALHADTITGAGDDAAVLRSGARLQVISTDHLRAFVDDPYLMARIAAVHALGDVCAM
GAAPQSALLSLIIPRMSDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSMGRELTIGLTVTGLLDGPAIGLTGARPGDAI
LLTKPLGTGVILAAEMRGLARGKDVEHALASMQRPLAAASKILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDL
PVLPGAEQLSAQGIRSSLWQSNASLEPRISRPASPISDLIYDPQTAGGLLAVVPSQSVTGLLSAFQAEGEPAFVIGRIEE
GPPRILVN

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=316, Percent_Identity=28.1645569620253, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI15011844, Length=348, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=5e-19,
Organism=Escherichia coli, GI1788062, Length=303, Percent_Identity=35.973597359736, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787352, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786619, Length=237, Percent_Identity=32.0675105485232, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17543426, Length=361, Percent_Identity=25.7617728531856, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24653602, Length=312, Percent_Identity=27.5641025641026, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24653604, Length=312, Percent_Identity=27.5641025641026, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574119, Length=318, Percent_Identity=24.8427672955975, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 76192; Mature: 76192

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPDWPLSRDLVLIGGGHTHALVLRKWGMNPLPGARVTLINPGAASPYTGMLPGHIAGHY
CCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
TRDELDIDLVRLARFAGARIVFDTACGLDLMAKRVHLTGRPPIRYDVVSIDIGATAELPG
CCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHEECCCCCCEEEEEEEECCCCCCCCC
IEGFTQHAHSVKPLGLFASAWQSFLEKAAMQGRPADCAVIGGGVAGVELALAMAYRLKTS
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCC
GLAEARITLIESGPGLLQATSAVTRRILMRALSRSGITVLTGAQVTRISSGAIALAGRES
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEECCCC
LPADFIVSAAGARPYPWLAETGLAHTGGFLNVGPDLRTLTDPDVFAAGDCAHLTHAPRPK
CCHHHHHCCCCCCCCCCHHHCCCCCCCCCEECCCCCCCCCCCCCEECCCHHHCCCCCCCC
AGVYAVRAAPILFENLRARLSGQTLREFAPQSDYLKLISKGDRSAVGHKHFFTLSGRSVW
CCEEEEHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCEEE
RLKDHIDKTFMARLHDLPAMRTPPPPRVRALDEEAETRSEPLCGGCGSKVGRQNLISALS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GLPPALHADTITGAGDDAAVLRSGARLQVISTDHLRAFVDDPYLMARIAAVHALGDVCAM
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHC
GAAPQSALLSLIIPRMSDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSMGRELTIGLTV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEE
TGLLDGPAIGLTGARPGDAILLTKPLGTGVILAAEMRGLARGKDVEHALASMQRPLAAAS
EEEECCCCEECCCCCCCCEEEEECCCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHH
KILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDLPVLPGAEQLSAQGIRSSLWQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
SNASLEPRISRPASPISDLIYDPQTAGGLLAVVPSQSVTGLLSAFQAEGEPAFVIGRIEE
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECC
GPPRILVN
CCCEEEEC
>Mature Secondary Structure
MHPDWPLSRDLVLIGGGHTHALVLRKWGMNPLPGARVTLINPGAASPYTGMLPGHIAGHY
CCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
TRDELDIDLVRLARFAGARIVFDTACGLDLMAKRVHLTGRPPIRYDVVSIDIGATAELPG
CCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHEECCCCCCEEEEEEEECCCCCCCCC
IEGFTQHAHSVKPLGLFASAWQSFLEKAAMQGRPADCAVIGGGVAGVELALAMAYRLKTS
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCC
GLAEARITLIESGPGLLQATSAVTRRILMRALSRSGITVLTGAQVTRISSGAIALAGRES
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEECCCC
LPADFIVSAAGARPYPWLAETGLAHTGGFLNVGPDLRTLTDPDVFAAGDCAHLTHAPRPK
CCHHHHHCCCCCCCCCCHHHCCCCCCCCCEECCCCCCCCCCCCCEECCCHHHCCCCCCCC
AGVYAVRAAPILFENLRARLSGQTLREFAPQSDYLKLISKGDRSAVGHKHFFTLSGRSVW
CCEEEEHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCEEE
RLKDHIDKTFMARLHDLPAMRTPPPPRVRALDEEAETRSEPLCGGCGSKVGRQNLISALS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GLPPALHADTITGAGDDAAVLRSGARLQVISTDHLRAFVDDPYLMARIAAVHALGDVCAM
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHC
GAAPQSALLSLIIPRMSDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSMGRELTIGLTV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEE
TGLLDGPAIGLTGARPGDAILLTKPLGTGVILAAEMRGLARGKDVEHALASMQRPLAAAS
EEEECCCCEECCCCCCCCEEEEECCCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHH
KILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDLPVLPGAEQLSAQGIRSSLWQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHH
SNASLEPRISRPASPISDLIYDPQTAGGLLAVVPSQSVTGLLSAFQAEGEPAFVIGRIEE
CCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECC
GPPRILVN
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA