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The map label for this gene is yafC [H]

Identifier: 114800127

GI number: 114800127

Start: 1383258

End: 1384166

Strand: Direct

Name: yafC [H]

Synonym: HNE_1349

Alternate gene names: 114800127

Gene position: 1383258-1384166 (Clockwise)

Preceding gene: 114800489

Following gene: 114799556

Centisome position: 37.33

GC content: 64.91

Gene sequence:

>909_bases
ATGAACATTGAAGCTGGCTCCTGGGACCATATCCGCTCTTTCCTTGCCGTGCTGGAGGAGGGCAGCCTTTCCCGCGCAGC
CCGCGTCCTGTCGCTGACCCAGCCGACGCTCTCCCGCCATATTGACCAGCTTGAAGCCACCCTCGGCGGGCCGCTGTTTA
CGCGCTCGCCGCGCGGCCTTATCCCGACGGACAAGGCGCGGATGATCGAGCCTTATGCGCGCACCATCGCCGCCTCGGCC
GCCGCCATGGCGCGGGCCGCTTCAGGCGCGGCGGGGGAGATGACCGGGGCAGTGCGCATCTCGGCCAGCGAAGTGGTCGG
CATTGAACTGCTACCGGAAATGCTTGCGCCCCTGCGCGAAGCTTATCCCGGCCTCACCTTTGAAATCCTGCCCACCAACC
AGTCGAGCGACCTGCTGCGCCGTGACGCCGACATCGCCGTGCGCATGGTGCGGCCCCAGCAGGGCGCGCTGCTGGCCAGA
AAGGTGGGCGATGTCATGCTCGGCCTCTTCGCCCGCCGCGACTATCTGGAAAAATACGGAACGCCCCGGAGCATGAAGGA
TGTCGCCGGGCACGCGCTCATCGGCTTTGACCATGAAACCATCAGCGTTCAGGCCCTGCGCGGAATGGGCCTGACACTGG
ACCGGGCTAGCTTTGCCTGGCGGACGGACAGTGACCTCGCCCAGACAAACCTCATCCGCGCCGGCGCCGGCATCGGGGTT
TGCCAGGCAGGGCTCGCCCGCCGCCATGGCGCACTTGTCCAGGTGCTGCCAGAGGACTTCACATTTCCGATGGAAACCTG
GGTGACGATGCATGAGGAACTCAAAGGCGTCACCCGAATGAAGGCTGTGTTCGATCATCTCAGCGAAGCGATGACGGCCT
ATATCCGCAACCAGGAAAGCCCCGCCTAA

Upstream 100 bases:

>100_bases
CCATCTTCCCGTCTCCTTTTGCTCTGGAATGTGCCAAGGATGGCGGAAGATAGAGATAAACATAATTGCGATAATAAATG
GATCAGATATAGAAAAATAA

Downstream 100 bases:

>100_bases
AGACCATCCATCCGGCAGCCGCGTGCTTCCAGAATCTCCCGCATTTCCCAATAGGCGCGGGGTGTGCGCATCAGGGGGAT
GCGCGGGTGCAGGTGGTGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MNIEAGSWDHIRSFLAVLEEGSLSRAARVLSLTQPTLSRHIDQLEATLGGPLFTRSPRGLIPTDKARMIEPYARTIAASA
AAMARAASGAAGEMTGAVRISASEVVGIELLPEMLAPLREAYPGLTFEILPTNQSSDLLRRDADIAVRMVRPQQGALLAR
KVGDVMLGLFARRDYLEKYGTPRSMKDVAGHALIGFDHETISVQALRGMGLTLDRASFAWRTDSDLAQTNLIRAGAGIGV
CQAGLARRHGALVQVLPEDFTFPMETWVTMHEELKGVTRMKAVFDHLSEAMTAYIRNQESPA

Sequences:

>Translated_302_residues
MNIEAGSWDHIRSFLAVLEEGSLSRAARVLSLTQPTLSRHIDQLEATLGGPLFTRSPRGLIPTDKARMIEPYARTIAASA
AAMARAASGAAGEMTGAVRISASEVVGIELLPEMLAPLREAYPGLTFEILPTNQSSDLLRRDADIAVRMVRPQQGALLAR
KVGDVMLGLFARRDYLEKYGTPRSMKDVAGHALIGFDHETISVQALRGMGLTLDRASFAWRTDSDLAQTNLIRAGAGIGV
CQAGLARRHGALVQVLPEDFTFPMETWVTMHEELKGVTRMKAVFDHLSEAMTAYIRNQESPA
>Mature_302_residues
MNIEAGSWDHIRSFLAVLEEGSLSRAARVLSLTQPTLSRHIDQLEATLGGPLFTRSPRGLIPTDKARMIEPYARTIAASA
AAMARAASGAAGEMTGAVRISASEVVGIELLPEMLAPLREAYPGLTFEILPTNQSSDLLRRDADIAVRMVRPQQGALLAR
KVGDVMLGLFARRDYLEKYGTPRSMKDVAGHALIGFDHETISVQALRGMGLTLDRASFAWRTDSDLAQTNLIRAGAGIGV
CQAGLARRHGALVQVLPEDFTFPMETWVTMHEELKGVTRMKAVFDHLSEAMTAYIRNQESPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=27.3684210526316, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI157672245, Length=135, Percent_Identity=36.2962962962963, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789639, Length=183, Percent_Identity=25.1366120218579, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=24, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=134, Percent_Identity=32.089552238806, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32838; Mature: 32838

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEAGSWDHIRSFLAVLEEGSLSRAARVLSLTQPTLSRHIDQLEATLGGPLFTRSPRGL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
IPTDKARMIEPYARTIAASAAAMARAASGAAGEMTGAVRISASEVVGIELLPEMLAPLRE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
AYPGLTFEILPTNQSSDLLRRDADIAVRMVRPQQGALLARKVGDVMLGLFARRDYLEKYG
HCCCCEEEEEECCCCHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPRSMKDVAGHALIGFDHETISVQALRGMGLTLDRASFAWRTDSDLAQTNLIRAGAGIGV
CCCCHHHHCCCEEEECCCCCEEHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCHH
CQAGLARRHGALVQVLPEDFTFPMETWVTMHEELKGVTRMKAVFDHLSEAMTAYIRNQES
HHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PA
CC
>Mature Secondary Structure
MNIEAGSWDHIRSFLAVLEEGSLSRAARVLSLTQPTLSRHIDQLEATLGGPLFTRSPRGL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
IPTDKARMIEPYARTIAASAAAMARAASGAAGEMTGAVRISASEVVGIELLPEMLAPLRE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
AYPGLTFEILPTNQSSDLLRRDADIAVRMVRPQQGALLARKVGDVMLGLFARRDYLEKYG
HCCCCEEEEEECCCCHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TPRSMKDVAGHALIGFDHETISVQALRGMGLTLDRASFAWRTDSDLAQTNLIRAGAGIGV
CCCCHHHHCCCEEEECCCCCEEHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCHH
CQAGLARRHGALVQVLPEDFTFPMETWVTMHEELKGVTRMKAVFDHLSEAMTAYIRNQES
HHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]