| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
Click here to switch to the map view.
The map label for this gene is slt [H]
Identifier: 114800029
GI number: 114800029
Start: 2962811
End: 2965003
Strand: Direct
Name: slt [H]
Synonym: HNE_2801
Alternate gene names: 114800029
Gene position: 2962811-2965003 (Clockwise)
Preceding gene: 114800014
Following gene: 114797083
Centisome position: 79.97
GC content: 68.4
Gene sequence:
>2193_bases ATGCTCCGGATTTCCGCTGTTTTTGTGGCGATTTCTTTCCTTCTTACAGGCACTTCGGCCGCCTCCCGGCCCGAAGCGCC CAGCCTGAAGCCGCGCGCCGATTCTCCGGCCCCGCCACCGGCCCAGATGGCCGAAACCACCCCGGCGCCCGTCCTGCGCG CGCTCACCCCCGGCGTCATCCTGCCCGGCGCGGCCCCCGCTCAGCCTGGCGCTGCGCCCGTGCCCACGCCCGCCGCCAAC GGCGCCCAGCTTCCGGCGGTCGCCCCCAGCGCCCTGACGGCTCAGCCGGTAAACCCCACCAGCGTCGCCCAGCTCAAAGC CGCCCTCTCCGCCATCGACCGCGGCGCATGGAGCGAAGTCACCCGCATCCAGTACGAAACGTCCGACCCCGCCGTGCGCG ACATGATCCTCTGGAAGCGCGCCTCCGACGGCGTGCCCGGCACCACCTTTGACGAAATCAACTACGCCCTCACCACCCTC TCGACCTGGCCGCTGACCGACCGGATGCGCCGCCGCGCCGAGGAAATCATCGGCGACAGCAACCTCACCGCCGAGGCCAA GGTGAAATGGCTGGAGGAGTCCGGCCCCATCACCGGCGCCGGCAAGGTCGCCCTCGCCACCGCGCTGCGCCAGTCTGGCC AGGCCGCCAGGGCGCAGGAAGTCATCCGCGATGTCTGGCGCAACAACACGCTGGAATCGAGCGTCCAGCGCACGGTGCTC GCCAGCTGGGGCCAATCGCTCAGCCAGGACGATCACCGCGCCCGCGTCGATTTCCTCCTCTGGACCGGCCAACGCTCAGA CGCCCAGGCCCTCAAGCCCCAGCTCACCGCCGACTATCGCAACCTCGTCGATGCCCGCATCGCCCTCTCCCAGCGCGCCC GCAATGTCGACGCCGCCATCGAGGCCGTGCCCGCTAATCTGCAAAACCATCCCGGCCTGCTGTATGAGCGCGCCAACTGG CGCCGCGCCAAGAATATGGACGACGCCGTCGCCCCGCTGCTCACCCAGATCAACGGCAAGGACGTGCCCGCTGCCGGGCG CGGCCGCCTCTGGGATGAGCGCGCCATCGCCATCCGCAATGATCTCAAGGCCCGCAACTATTCGCGTGCCTACGCGATGG CCGCCCCCCACGGCATGAGCGCGGGCGCAGACTTTGCCGAGGCCGAATGGCTCTCGGGCTGGATCGCCCTGCGCCTGAAT GGCGACGCGACCCGCGGCCTCAAGCATTTCGAGACCATGACTAATGGCGTCGGCTCGCCCGTCAGCCTCACGCGGGGCCA GTACTGGACCGGCCGCGCGCGCGATGCGCTGGGCCAGTCAGACCAGGCAGCCCTCGCCTACAGCGCGGCGGCCGCCCACA AATACACTTATTACGGACAGCTTTCGGCCGAGCGGCTTGGCGACCGGACCATCAATTTCGGCCCCGCGATTGCTCCGGCC CCGGAAGAACTCGCCGCCTTCGATACAAACCCGATGGTCCGCGCGCTCCGCCTCATCGGCGCCACGGGGGAGATGGGTCT CTACCGCACCTTCTCCCACCATCTGGATGACATCCTCTCCACCCCGGCAGAGTTCGAGCTGCTGGCCCAGCTGAACCACC AGTATGACCAGCCCGACACCGCCGTGCGCGCGGGCAAGGCCGGTCTCTTCAAGGGCGTCCTCGCGCCGGACGCCGCCTAT CCCATCCTGATGCACCCGCTCTCACGCCAGCCGGAAGTCGAACGCGCCTTCATCCTCGCCATCACGCGCCAGGAGAGCGA GTTCAACCCCAACGCCCGCAGCCCCGTCGGCGCCCTCGGCCTGATGCAGTTCATGCCATCAACCGCCCGCAACGAAGCCC GCCTGCGCGGCATGCCATACGAACAGTCCTGGCTGACGAATGACCCCGCCTACAACATGACGCTCGGCGGGCTCCATCTC GACACGTTGCTGAAGCAGTTCAACGGCAGCTACATCATGACGGCGGCCGCCTACAACGCCGGCCCCTCCCGCCCCAGCCA ATGGGCCCGCGACTATGGCGACCCCCGCACCGGCCAGATCGACCCCGTCGACTGGGTCGAGTTCGTCCCCTTCTCCGAGA CGCGCAACTACATCCAGCGCGTCCTGGAAAACATCCAGGTCTACCGCCACCGCATCTCCGGCGAAGAAGCCGACATCCAG ATCACGGAAGACCTCAAACGCGGCCGCCGCTGA
Upstream 100 bases:
>100_bases TTAACGTGCCGTATTCAGGGATTGGTTGGGATTGCGTGCTAGGCTCTGTCTCTGGACTTGTCACGCTTTGGCGCAGAAAT AAACTTGGGTGAGCCGAACC
Downstream 100 bases:
>100_bases CCGGAAGTGTCCCGGTTTGTCCAGATTTGTCCAAACCTGTCCGGAAGTGTCCGGGCCTGACGCTTGGAGTTCCGTTGGAG CTTCGTTGGAGTTTTCCGCA
Product: Slt family transglycosylase
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 730; Mature: 730
Protein sequence:
>730_residues MLRISAVFVAISFLLTGTSAASRPEAPSLKPRADSPAPPPAQMAETTPAPVLRALTPGVILPGAAPAQPGAAPVPTPAAN GAQLPAVAPSALTAQPVNPTSVAQLKAALSAIDRGAWSEVTRIQYETSDPAVRDMILWKRASDGVPGTTFDEINYALTTL STWPLTDRMRRRAEEIIGDSNLTAEAKVKWLEESGPITGAGKVALATALRQSGQAARAQEVIRDVWRNNTLESSVQRTVL ASWGQSLSQDDHRARVDFLLWTGQRSDAQALKPQLTADYRNLVDARIALSQRARNVDAAIEAVPANLQNHPGLLYERANW RRAKNMDDAVAPLLTQINGKDVPAAGRGRLWDERAIAIRNDLKARNYSRAYAMAAPHGMSAGADFAEAEWLSGWIALRLN GDATRGLKHFETMTNGVGSPVSLTRGQYWTGRARDALGQSDQAALAYSAAAAHKYTYYGQLSAERLGDRTINFGPAIAPA PEELAAFDTNPMVRALRLIGATGEMGLYRTFSHHLDDILSTPAEFELLAQLNHQYDQPDTAVRAGKAGLFKGVLAPDAAY PILMHPLSRQPEVERAFILAITRQESEFNPNARSPVGALGLMQFMPSTARNEARLRGMPYEQSWLTNDPAYNMTLGGLHL DTLLKQFNGSYIMTAAAYNAGPSRPSQWARDYGDPRTGQIDPVDWVEFVPFSETRNYIQRVLENIQVYRHRISGEEADIQ ITEDLKRGRR
Sequences:
>Translated_730_residues MLRISAVFVAISFLLTGTSAASRPEAPSLKPRADSPAPPPAQMAETTPAPVLRALTPGVILPGAAPAQPGAAPVPTPAAN GAQLPAVAPSALTAQPVNPTSVAQLKAALSAIDRGAWSEVTRIQYETSDPAVRDMILWKRASDGVPGTTFDEINYALTTL STWPLTDRMRRRAEEIIGDSNLTAEAKVKWLEESGPITGAGKVALATALRQSGQAARAQEVIRDVWRNNTLESSVQRTVL ASWGQSLSQDDHRARVDFLLWTGQRSDAQALKPQLTADYRNLVDARIALSQRARNVDAAIEAVPANLQNHPGLLYERANW RRAKNMDDAVAPLLTQINGKDVPAAGRGRLWDERAIAIRNDLKARNYSRAYAMAAPHGMSAGADFAEAEWLSGWIALRLN GDATRGLKHFETMTNGVGSPVSLTRGQYWTGRARDALGQSDQAALAYSAAAAHKYTYYGQLSAERLGDRTINFGPAIAPA PEELAAFDTNPMVRALRLIGATGEMGLYRTFSHHLDDILSTPAEFELLAQLNHQYDQPDTAVRAGKAGLFKGVLAPDAAY PILMHPLSRQPEVERAFILAITRQESEFNPNARSPVGALGLMQFMPSTARNEARLRGMPYEQSWLTNDPAYNMTLGGLHL DTLLKQFNGSYIMTAAAYNAGPSRPSQWARDYGDPRTGQIDPVDWVEFVPFSETRNYIQRVLENIQVYRHRISGEEADIQ ITEDLKRGRR >Mature_730_residues MLRISAVFVAISFLLTGTSAASRPEAPSLKPRADSPAPPPAQMAETTPAPVLRALTPGVILPGAAPAQPGAAPVPTPAAN GAQLPAVAPSALTAQPVNPTSVAQLKAALSAIDRGAWSEVTRIQYETSDPAVRDMILWKRASDGVPGTTFDEINYALTTL STWPLTDRMRRRAEEIIGDSNLTAEAKVKWLEESGPITGAGKVALATALRQSGQAARAQEVIRDVWRNNTLESSVQRTVL ASWGQSLSQDDHRARVDFLLWTGQRSDAQALKPQLTADYRNLVDARIALSQRARNVDAAIEAVPANLQNHPGLLYERANW RRAKNMDDAVAPLLTQINGKDVPAAGRGRLWDERAIAIRNDLKARNYSRAYAMAAPHGMSAGADFAEAEWLSGWIALRLN GDATRGLKHFETMTNGVGSPVSLTRGQYWTGRARDALGQSDQAALAYSAAAAHKYTYYGQLSAERLGDRTINFGPAIAPA PEELAAFDTNPMVRALRLIGATGEMGLYRTFSHHLDDILSTPAEFELLAQLNHQYDQPDTAVRAGKAGLFKGVLAPDAAY PILMHPLSRQPEVERAFILAITRQESEFNPNARSPVGALGLMQFMPSTARNEARLRGMPYEQSWLTNDPAYNMTLGGLHL DTLLKQFNGSYIMTAAAYNAGPSRPSQWARDYGDPRTGQIDPVDWVEFVPFSETRNYIQRVLENIQVYRHRISGEEADIQ ITEDLKRGRR
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=166, Percent_Identity=37.9518072289157, Blast_Score=112, Evalue=1e-25,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 79619; Mature: 79619
Theoretical pI: Translated: 8.53; Mature: 8.53
Prosite motif: PS00922 TRANSGLYCOSYLASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLRISAVFVAISFLLTGTSAASRPEAPSLKPRADSPAPPPAQMAETTPAPVLRALTPGVI CEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCEE LPGAAPAQPGAAPVPTPAANGAQLPAVAPSALTAQPVNPTSVAQLKAALSAIDRGAWSEV CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH TRIQYETSDPAVRDMILWKRASDGVPGTTFDEINYALTTLSTWPLTDRMRRRAEEIIGDS HEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC NLTAEAKVKWLEESGPITGAGKVALATALRQSGQAARAQEVIRDVWRNNTLESSVQRTVL CCCHHHHHEEHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHH ASWGQSLSQDDHRARVDFLLWTGQRSDAQALKPQLTADYRNLVDARIALSQRARNVDAAI HHHHHHHCCCCHHCEEEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHH EAVPANLQNHPGLLYERANWRRAKNMDDAVAPLLTQINGKDVPAAGRGRLWDERAIAIRN HHHCCCCCCCCCCEEECCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH DLKARNYSRAYAMAAPHGMSAGADFAEAEWLSGWIALRLNGDATRGLKHFETMTNGVGSP HHHHCCCCHHEEEECCCCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCC VSLTRGQYWTGRARDALGQSDQAALAYSAAAAHKYTYYGQLSAERLGDRTINFGPAIAPA CEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCEEEECCCCHHHHCCCCCCCCCCCCCC PEELAAFDTNPMVRALRLIGATGEMGLYRTFSHHLDDILSTPAEFELLAQLNHQYDQPDT HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH AVRAGKAGLFKGVLAPDAAYPILMHPLSRQPEVERAFILAITRQESEFNPNARSPVGALG HHHHCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH LMQFMPSTARNEARLRGMPYEQSWLTNDPAYNMTLGGLHLDTLLKQFNGSYIMTAAAYNA HHHHCCCHHCCCHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCEEEEEEECCC GPSRPSQWARDYGDPRTGQIDPVDWVEFVPFSETRNYIQRVLENIQVYRHRISGEEADIQ CCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE ITEDLKRGRR EHHHHHCCCC >Mature Secondary Structure MLRISAVFVAISFLLTGTSAASRPEAPSLKPRADSPAPPPAQMAETTPAPVLRALTPGVI CEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCCEE LPGAAPAQPGAAPVPTPAANGAQLPAVAPSALTAQPVNPTSVAQLKAALSAIDRGAWSEV CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH TRIQYETSDPAVRDMILWKRASDGVPGTTFDEINYALTTLSTWPLTDRMRRRAEEIIGDS HEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC NLTAEAKVKWLEESGPITGAGKVALATALRQSGQAARAQEVIRDVWRNNTLESSVQRTVL CCCHHHHHEEHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHH ASWGQSLSQDDHRARVDFLLWTGQRSDAQALKPQLTADYRNLVDARIALSQRARNVDAAI HHHHHHHCCCCHHCEEEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHH EAVPANLQNHPGLLYERANWRRAKNMDDAVAPLLTQINGKDVPAAGRGRLWDERAIAIRN HHHCCCCCCCCCCEEECCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH DLKARNYSRAYAMAAPHGMSAGADFAEAEWLSGWIALRLNGDATRGLKHFETMTNGVGSP HHHHCCCCHHEEEECCCCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCC VSLTRGQYWTGRARDALGQSDQAALAYSAAAAHKYTYYGQLSAERLGDRTINFGPAIAPA CEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCEEEECCCCHHHHCCCCCCCCCCCCCC PEELAAFDTNPMVRALRLIGATGEMGLYRTFSHHLDDILSTPAEFELLAQLNHQYDQPDT HHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH AVRAGKAGLFKGVLAPDAAYPILMHPLSRQPEVERAFILAITRQESEFNPNARSPVGALG HHHHCCHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH LMQFMPSTARNEARLRGMPYEQSWLTNDPAYNMTLGGLHLDTLLKQFNGSYIMTAAAYNA HHHHCCCHHCCCHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCEEEEEEECCC GPSRPSQWARDYGDPRTGQIDPVDWVEFVPFSETRNYIQRVLENIQVYRHRISGEEADIQ CCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE ITEDLKRGRR EHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]