Click here to switch to the map view.

The map label for this gene is bioI [H]

Identifier: 114800014

GI number: 114800014

Start: 2959410

End: 2960672

Strand: Direct

Name: bioI [H]

Synonym: HNE_2797

Alternate gene names: 114800014

Gene position: 2959410-2960672 (Clockwise)

Preceding gene: 114797612

Following gene: 114800029

Centisome position: 79.88

GC content: 65.4

Gene sequence:

>1263_bases
ATGCCAGACATCGCATCGCTCACAAGTCTGGAATCCCTCGGTTTCACCGGTGGCCGTGACAGCTTCCGCGCCTTCTGCGC
CCGCGTCTTTGCTGATGACGCCCCCCGCCTCCTGCGCACGGAAGCGGGCGAGCTTGTCGTTTTCCGCCATGGCGATCTGC
GCGCGTTCGGCGCCCTGCCGGAGGTCGGCGCCCTGCCGCCCGGCGTCATGTTTCCCGGCCTCCACCAGCTTCCCCCCGGC
GCGCCGCTCCCGCCGGGCGGGGGCATCGGCGGCGTCATCTCCCATCAGGTGTTCACCGCAAATCCGCCCATCCACATGCC
GGTGCGCCTCACCCTGCTGCGTCAGTTAAGCCCCAAACAGGCCGCGCTTCTGGAGCCGGTTGCACGCAATGTCGTGCAAG
GTCTGCTCGACACCCTGAAACACCGGGACGAGATCGACCTTGTGGAAGACATCGCCGAGCGCCTCACCGCGCGCTTCTGG
GGCGCCCTCATCGGCATGACCGAAACGGAAATGGCTGAAGCCGCGCTGGCCGTGCGCGACATGACAGCGATGTTCCTTAT
CCAGATGACGAGAGGCGATCTCCAAACAGCCGACACCGCAACCGCCACCTATGGCCGCCTCGTCGAAACCGCCGCCCTGC
GCAGCCTTGCCGCCGGCACACATCCCTTCGTCACCGAGCTGGCCGCAGACCTCGCAAAGATCGAGGCACAGGATGATCCC
GATGAAGCTGGAATCGTCCCGCCCAATGTGGGCAAGCTGCTGGCGGGCAATCTCGTCGACGGCTTCCACACAGCCGCCAT
CGGCGCGGTCAACACCCTCTTCGCCCTGCTGCAACACCCTGATACGTTCACGGAGGTTCTCGCCGCTCCGGAAAAACTTC
CCGCCGTCATCATGGAGGCCCTGCGGCTGGAGCCGCCCGTCCTCTTCCTGAGGCGCTATATGCTGCGCGATCTCGATTAT
GCCGGCATCCACATTCCCAAAGGCACACAGGTGCTCATGCTATGGGCCGCGGGCAATCACGACCCCGCGGTCTTCCCCAA
GCCCCAGATTTTCCGTCTGGACCGCGATCATCGCGGCATCACCACCTTCGGCGGCGGCGCGCATATCTGCCCCGGCCGCC
ACGTCGCGCTGATGCTCATCCGCCTGCTGCTGGAAGAAATCGCCGCACGCGGCCTCCGCCTCTCCTTCACCGATGCCCCT
TATGCCTGGCTCGGCAACCATGCCATGAGCCAGCTCCCGCATATGCGTTTTAGGGTGGGGTAG

Upstream 100 bases:

>100_bases
ACGCTTTGATCCCGGCGCCAACAAAATCTCACCAAACATTGCCAGACCGGCCCCTTCATGTTCAGTAGTGATAACTATCG
AACATGAAGGGGCTGCGCCC

Downstream 100 bases:

>100_bases
CAGCATTAAAAAATGCAGACTGATTTACATAGGTAATGCTTGAGGTAGGGGCGGCATGCTAAAAACTCATTTCTCTGACT
TTGGGATCAACGTGCGCCAG

Product: cytochrome P450 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MPDIASLTSLESLGFTGGRDSFRAFCARVFADDAPRLLRTEAGELVVFRHGDLRAFGALPEVGALPPGVMFPGLHQLPPG
APLPPGGGIGGVISHQVFTANPPIHMPVRLTLLRQLSPKQAALLEPVARNVVQGLLDTLKHRDEIDLVEDIAERLTARFW
GALIGMTETEMAEAALAVRDMTAMFLIQMTRGDLQTADTATATYGRLVETAALRSLAAGTHPFVTELAADLAKIEAQDDP
DEAGIVPPNVGKLLAGNLVDGFHTAAIGAVNTLFALLQHPDTFTEVLAAPEKLPAVIMEALRLEPPVLFLRRYMLRDLDY
AGIHIPKGTQVLMLWAAGNHDPAVFPKPQIFRLDRDHRGITTFGGGAHICPGRHVALMLIRLLLEEIAARGLRLSFTDAP
YAWLGNHAMSQLPHMRFRVG

Sequences:

>Translated_420_residues
MPDIASLTSLESLGFTGGRDSFRAFCARVFADDAPRLLRTEAGELVVFRHGDLRAFGALPEVGALPPGVMFPGLHQLPPG
APLPPGGGIGGVISHQVFTANPPIHMPVRLTLLRQLSPKQAALLEPVARNVVQGLLDTLKHRDEIDLVEDIAERLTARFW
GALIGMTETEMAEAALAVRDMTAMFLIQMTRGDLQTADTATATYGRLVETAALRSLAAGTHPFVTELAADLAKIEAQDDP
DEAGIVPPNVGKLLAGNLVDGFHTAAIGAVNTLFALLQHPDTFTEVLAAPEKLPAVIMEALRLEPPVLFLRRYMLRDLDY
AGIHIPKGTQVLMLWAAGNHDPAVFPKPQIFRLDRDHRGITTFGGGAHICPGRHVALMLIRLLLEEIAARGLRLSFTDAP
YAWLGNHAMSQLPHMRFRVG
>Mature_419_residues
PDIASLTSLESLGFTGGRDSFRAFCARVFADDAPRLLRTEAGELVVFRHGDLRAFGALPEVGALPPGVMFPGLHQLPPGA
PLPPGGGIGGVISHQVFTANPPIHMPVRLTLLRQLSPKQAALLEPVARNVVQGLLDTLKHRDEIDLVEDIAERLTARFWG
ALIGMTETEMAEAALAVRDMTAMFLIQMTRGDLQTADTATATYGRLVETAALRSLAAGTHPFVTELAADLAKIEAQDDPD
EAGIVPPNVGKLLAGNLVDGFHTAAIGAVNTLFALLQHPDTFTEVLAAPEKLPAVIMEALRLEPPVLFLRRYMLRDLDYA
GIHIPKGTQVLMLWAAGNHDPAVFPKPQIFRLDRDHRGITTFGGGAHICPGRHVALMLIRLLLEEIAARGLRLSFTDAPY
AWLGNHAMSQLPHMRFRVG

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 45426; Mature: 45295

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDIASLTSLESLGFTGGRDSFRAFCARVFADDAPRLLRTEAGELVVFRHGDLRAFGALP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCHHHCCCC
EVGALPPGVMFPGLHQLPPGAPLPPGGGIGGVISHQVFTANPPIHMPVRLTLLRQLSPKQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEECCCCCCCHHHHHHHHHCCCHH
AALLEPVARNVVQGLLDTLKHRDEIDLVEDIAERLTARFWGALIGMTETEMAEAALAVRD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MTAMFLIQMTRGDLQTADTATATYGRLVETAALRSLAAGTHPFVTELAADLAKIEAQDDP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
DEAGIVPPNVGKLLAGNLVDGFHTAAIGAVNTLFALLQHPDTFTEVLAAPEKLPAVIMEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHH
LRLEPPVLFLRRYMLRDLDYAGIHIPKGTQVLMLWAAGNHDPAVFPKPQIFRLDRDHRGI
HHCCCHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCC
TTFGGGAHICPGRHVALMLIRLLLEEIAARGLRLSFTDAPYAWLGNHAMSQLPHMRFRVG
EEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCHHHHHCCCCCEECC
>Mature Secondary Structure 
PDIASLTSLESLGFTGGRDSFRAFCARVFADDAPRLLRTEAGELVVFRHGDLRAFGALP
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCHHHCCCC
EVGALPPGVMFPGLHQLPPGAPLPPGGGIGGVISHQVFTANPPIHMPVRLTLLRQLSPKQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEECCCCCCCHHHHHHHHHCCCHH
AALLEPVARNVVQGLLDTLKHRDEIDLVEDIAERLTARFWGALIGMTETEMAEAALAVRD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MTAMFLIQMTRGDLQTADTATATYGRLVETAALRSLAAGTHPFVTELAADLAKIEAQDDP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
DEAGIVPPNVGKLLAGNLVDGFHTAAIGAVNTLFALLQHPDTFTEVLAAPEKLPAVIMEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHH
LRLEPPVLFLRRYMLRDLDYAGIHIPKGTQVLMLWAAGNHDPAVFPKPQIFRLDRDHRGI
HHCCCHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCC
TTFGGGAHICPGRHVALMLIRLLLEEIAARGLRLSFTDAPYAWLGNHAMSQLPHMRFRVG
EEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]