Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 114799906

GI number: 114799906

Start: 2937953

End: 2938846

Strand: Direct

Name: nahR [H]

Synonym: HNE_2774

Alternate gene names: 114799906

Gene position: 2937953-2938846 (Clockwise)

Preceding gene: 114799162

Following gene: 114800273

Centisome position: 79.3

GC content: 65.66

Gene sequence:

>894_bases
ATGAACCTCCGGTCTCTTGATCTCAATCTCCTGCCTGTGCTGGAGGCGATTTACGCCGAGCGCAGCCTGACGCGCGCCAG
CGAAGTGCTTCACATCACCCAGCCCGCCGTCAGCAACGCGCTCTCGCGCCTGCGCCTGCATTTTGAAGACCCGCTCTTCG
TGCGCGAGGGCCGCGGGGTGAAGCCCACCGCGATGACCGAAGCCCTGATGCCGGCGATCCGGGAATCCCTCGACAAGCTG
CGCAACGGGCTCGAGCCGCGCTCGGTGTTTGAGCCCTCGCGCTCCACCCGCGTGTTCAATATCTCCAGCCGGGACGCGAG
CGCGCACATTCTCGCCCCGCCGATTGCCCGCCGCCTGGAAGTGCAGGCGCCCGGCGTGCGTATCTCCTGGAGCCAGCCCC
AGCGCTCGGCCATCGCCAGCGAGCTGGCTTCAGGGCGTCTCGACCTTGCCATCGACGTGCAGGACCTGCGCGGGGCAGAC
CTTGAACGTGTGCTGCTCTCCTCCACCAAATATGTCTGCGCGCTGGCGAGCGACCATCCGCTGGCAAACGAACCGCTGAC
GCTGGATAAATTCTTCAGCATGCGCCATATCGCCGTCTCCAGCCGCCGCGAAGGGCGCAGCCTGATCGAGGAGATGGCGC
GCTCTCTGGGACACCGGATCACGCCCGTTCACCGCCTGCCCCACTATCAGCCTGCCCTGGAGGTTGTGCGCTGTACGCAT
CTCGCCCTCGCCGCGCCCCAGCCGGTCACCGAAGGCTCTGGCCTGGCCGTGATGAAGTTGCCGTTTGATTTTCCCTCGCC
CGGCTCGATGCTCTACTGGCATCGCGAATATGCACAGGACCCGGCCCTGATGTGGCTGCGCGGGCTTATCCGGGATGTCT
CCGTCACGCTTTAA

Upstream 100 bases:

>100_bases
CACACATGGCGCATGCAAGACTATTCGGCTACTTTATTTTATGAAACAATATCATCACTCGCCGTGATAATACGTTCCTG
TTCCTCCCACAGGCCCTGCC

Downstream 100 bases:

>100_bases
TCTGTGCACGCATCAGCAATGCATCAGGCGCGCCGGTATTCCTCGTCCCGCACAACCGCGAGAATGTCCCGCACGGTTTC
GGTTTCATAGCCGAAGCCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLRSLDLNLLPVLEAIYAERSLTRASEVLHITQPAVSNALSRLRLHFEDPLFVREGRGVKPTAMTEALMPAIRESLDKL
RNGLEPRSVFEPSRSTRVFNISSRDASAHILAPPIARRLEVQAPGVRISWSQPQRSAIASELASGRLDLAIDVQDLRGAD
LERVLLSSTKYVCALASDHPLANEPLTLDKFFSMRHIAVSSRREGRSLIEEMARSLGHRITPVHRLPHYQPALEVVRCTH
LALAAPQPVTEGSGLAVMKLPFDFPSPGSMLYWHREYAQDPALMWLRGLIRDVSVTL

Sequences:

>Translated_297_residues
MNLRSLDLNLLPVLEAIYAERSLTRASEVLHITQPAVSNALSRLRLHFEDPLFVREGRGVKPTAMTEALMPAIRESLDKL
RNGLEPRSVFEPSRSTRVFNISSRDASAHILAPPIARRLEVQAPGVRISWSQPQRSAIASELASGRLDLAIDVQDLRGAD
LERVLLSSTKYVCALASDHPLANEPLTLDKFFSMRHIAVSSRREGRSLIEEMARSLGHRITPVHRLPHYQPALEVVRCTH
LALAAPQPVTEGSGLAVMKLPFDFPSPGSMLYWHREYAQDPALMWLRGLIRDVSVTL
>Mature_297_residues
MNLRSLDLNLLPVLEAIYAERSLTRASEVLHITQPAVSNALSRLRLHFEDPLFVREGRGVKPTAMTEALMPAIRESLDKL
RNGLEPRSVFEPSRSTRVFNISSRDASAHILAPPIARRLEVQAPGVRISWSQPQRSAIASELASGRLDLAIDVQDLRGAD
LERVLLSSTKYVCALASDHPLANEPLTLDKFFSMRHIAVSSRREGRSLIEEMARSLGHRITPVHRLPHYQPALEVVRCTH
LALAAPQPVTEGSGLAVMKLPFDFPSPGSMLYWHREYAQDPALMWLRGLIRDVSVTL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=290, Percent_Identity=31.3793103448276, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87081766, Length=179, Percent_Identity=28.4916201117318, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790147, Length=309, Percent_Identity=25.2427184466019, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786820, Length=63, Percent_Identity=50.7936507936508, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33137; Mature: 33137

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRSLDLNLLPVLEAIYAERSLTRASEVLHITQPAVSNALSRLRLHFEDPLFVREGRGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHCCCCEEEECCCCC
KPTAMTEALMPAIRESLDKLRNGLEPRSVFEPSRSTRVFNISSRDASAHILAPPIARRLE
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCEEECCHHHHHEE
VQAPGVRISWSQPQRSAIASELASGRLDLAIDVQDLRGADLERVLLSSTKYVCALASDHP
ECCCCEEEECCCCHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHCCCCEEEEEECCCC
LANEPLTLDKFFSMRHIAVSSRREGRSLIEEMARSLGHRITPVHRLPHYQPALEVVRCTH
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHH
LALAAPQPVTEGSGLAVMKLPFDFPSPGSMLYWHREYAQDPALMWLRGLIRDVSVTL
HHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLRSLDLNLLPVLEAIYAERSLTRASEVLHITQPAVSNALSRLRLHFEDPLFVREGRGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHCCCCEEEECCCCC
KPTAMTEALMPAIRESLDKLRNGLEPRSVFEPSRSTRVFNISSRDASAHILAPPIARRLE
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCCEEECCHHHHHEE
VQAPGVRISWSQPQRSAIASELASGRLDLAIDVQDLRGADLERVLLSSTKYVCALASDHP
ECCCCEEEECCCCHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHCCCCEEEEEECCCC
LANEPLTLDKFFSMRHIAVSSRREGRSLIEEMARSLGHRITPVHRLPHYQPALEVVRCTH
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHH
LALAAPQPVTEGSGLAVMKLPFDFPSPGSMLYWHREYAQDPALMWLRGLIRDVSVTL
HHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]