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The map label for this gene is aglA [H]

Identifier: 114799867

GI number: 114799867

Start: 1778583

End: 1780199

Strand: Direct

Name: aglA [H]

Synonym: HNE_1737

Alternate gene names: 114799867

Gene position: 1778583-1780199 (Clockwise)

Preceding gene: 114799205

Following gene: 114799637

Centisome position: 48.0

GC content: 59.62

Gene sequence:

>1617_bases
ATGAGCCCTGAGACGCAACCCTGGTGGCGCGGCGCTGTGATCTACCAGATTTATCCGCGCTCTTATCAGGACTCCAATTC
GGACGGGGTGGGCGATCTGCCGGGTATTACCCGCCGGCTGGATCACATCGCTTCCCTTGGCGTCTCCGCGATCTGGATTT
CGCCGTTCTTCAAGTCGCCGATGAAGGATTTCGGCTACGATGTATCGGACTATTGCGATGTCGATCCGGCGTTCGGGACG
CTGGCGGATTTCGATACGCTCATGGAGCGAGCGCGCAGCCTTGGCCTGAAGGTCATTATTGATCAGGTGTATGCTCACAC
ATCTGACGCGCATGCCTGGTTTGCTGAAAGCCGGGCATCGCGGGCAAATCCCAAAGCTGACTGGTTTGTCTGGCGCGATG
CAAAGCCTGATGGAACGCCGCCCAATAACTGGCAGTCCGTTTTCGGCGGTCCGGCCTGGACCTGGGACGCGCGGCGCGGC
CAGTATTTCATGCACAACTTCCTTTCCAGCCAGCCTCAGCTGAATGTCCATAATCCGGAGGTTCAGGACGCGTTGCTAAG
CGTGGCAAAGTTCTGGCTGGACCGGGGCGTGGACGGTTTCCGGCTCGATGCGATCAACTTCGCCATGTTCGATCCCGAAT
TTCGGGACAACCCACCCTGGCCTGCGGAAGGGCGCACGATCACCCGGCCGTTTGACCTTCAGCATCACATTCACAACCAG
TCCCATCCTGATATTCCGGTATTCATGGAACGGGTGCGCGCCCTGGCCGACACCTATGGGGATATTTATACCGTAGCAGA
GGTGCCGGGCCCCGATCCGCTGCCGGAAATGCGGGCGTTCACGTCCGAGGGCCGGCTAAGCTCTGCCTACAGTTTTGATT
TTCTTTACGCCAAATCGCTTTCGCCGCGGCGCGTAAAAGCTTCCCAGATGAACTGGGCGGGGCCGTTGAGTGAAGGCTGG
GCGGCATGGGCCTTTTCCAATCATGACGCGCCGCGCTGCATCAGCCGTTGGTGTCCGCCCGGCGGTGATCTTGAAGCGTA
TGCCAAGATGACCAATGCGTTGCTGCTGTGCCTGCGCGGCAACCCGATCCTCTATCAGGGAGAGGAGCTGGGTCTCACCC
AGGCAGAGATTGCTTTTGAGGATTTGCAAGACCCCGAAGCCATCGCCAACTGGCCGCTGACACTGGGCCGGGACGGTGCG
CGCACGCCGATGCCCTGGATCAACGACAACAGCTATGCCGGGTTCTCCGAAGTCAAACCCTGGTTGCCGGTGGGCGCGGG
CCACGCCTTGCGGGCGGCAATGGCCCAGTATGGGCAGCCATTTTCCGTGCTCGAATTTACCAGGCTCGTAATCTCACTGC
GCAGCAGTTCCGACATTCTGAAGTTCGGAAGCGTCAGCTTTCCAGAAACTCAGGGCGACCTGCTGGCCATTGAGCGTCGC
CTCGGAGAGGACCGTCTCCTCTGCCTCTTCAATCTGGGGATCAAAGCTGTGTCAGTGGACGTCGCCCTGCCAAGGTTCGC
CACGACACTGCTGTCTTCGGATGGGCGACTTGAGGGGCCTGAAAATCTGCCTCCATTTGGAGTCTGGATTGGAACTGTCG
GGCCGCACTCCGACTGA

Upstream 100 bases:

>100_bases
TTTTCAAGACGGTGGCCTGGTGCTTTTCAGCACCTGGGCCCCCTTGTCATTCGTGACGCAGCGGCAGAGACCTTGAGGGA
AGCAATCTGCGGAGTTTCCC

Downstream 100 bases:

>100_bases
CCAACGTTGTCATTTTGATCCAAAGCGACTTATAAGACCTGGAACGGCTTCGGGTATCCCGAAGCCCCCTCAGAAAGGAA
GCGCCCACGGTGGCAAAGTT

Product: glycosy hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MSPETQPWWRGAVIYQIYPRSYQDSNSDGVGDLPGITRRLDHIASLGVSAIWISPFFKSPMKDFGYDVSDYCDVDPAFGT
LADFDTLMERARSLGLKVIIDQVYAHTSDAHAWFAESRASRANPKADWFVWRDAKPDGTPPNNWQSVFGGPAWTWDARRG
QYFMHNFLSSQPQLNVHNPEVQDALLSVAKFWLDRGVDGFRLDAINFAMFDPEFRDNPPWPAEGRTITRPFDLQHHIHNQ
SHPDIPVFMERVRALADTYGDIYTVAEVPGPDPLPEMRAFTSEGRLSSAYSFDFLYAKSLSPRRVKASQMNWAGPLSEGW
AAWAFSNHDAPRCISRWCPPGGDLEAYAKMTNALLLCLRGNPILYQGEELGLTQAEIAFEDLQDPEAIANWPLTLGRDGA
RTPMPWINDNSYAGFSEVKPWLPVGAGHALRAAMAQYGQPFSVLEFTRLVISLRSSSDILKFGSVSFPETQGDLLAIERR
LGEDRLLCLFNLGIKAVSVDVALPRFATTLLSSDGRLEGPENLPPFGVWIGTVGPHSD

Sequences:

>Translated_538_residues
MSPETQPWWRGAVIYQIYPRSYQDSNSDGVGDLPGITRRLDHIASLGVSAIWISPFFKSPMKDFGYDVSDYCDVDPAFGT
LADFDTLMERARSLGLKVIIDQVYAHTSDAHAWFAESRASRANPKADWFVWRDAKPDGTPPNNWQSVFGGPAWTWDARRG
QYFMHNFLSSQPQLNVHNPEVQDALLSVAKFWLDRGVDGFRLDAINFAMFDPEFRDNPPWPAEGRTITRPFDLQHHIHNQ
SHPDIPVFMERVRALADTYGDIYTVAEVPGPDPLPEMRAFTSEGRLSSAYSFDFLYAKSLSPRRVKASQMNWAGPLSEGW
AAWAFSNHDAPRCISRWCPPGGDLEAYAKMTNALLLCLRGNPILYQGEELGLTQAEIAFEDLQDPEAIANWPLTLGRDGA
RTPMPWINDNSYAGFSEVKPWLPVGAGHALRAAMAQYGQPFSVLEFTRLVISLRSSSDILKFGSVSFPETQGDLLAIERR
LGEDRLLCLFNLGIKAVSVDVALPRFATTLLSSDGRLEGPENLPPFGVWIGTVGPHSD
>Mature_537_residues
SPETQPWWRGAVIYQIYPRSYQDSNSDGVGDLPGITRRLDHIASLGVSAIWISPFFKSPMKDFGYDVSDYCDVDPAFGTL
ADFDTLMERARSLGLKVIIDQVYAHTSDAHAWFAESRASRANPKADWFVWRDAKPDGTPPNNWQSVFGGPAWTWDARRGQ
YFMHNFLSSQPQLNVHNPEVQDALLSVAKFWLDRGVDGFRLDAINFAMFDPEFRDNPPWPAEGRTITRPFDLQHHIHNQS
HPDIPVFMERVRALADTYGDIYTVAEVPGPDPLPEMRAFTSEGRLSSAYSFDFLYAKSLSPRRVKASQMNWAGPLSEGWA
AWAFSNHDAPRCISRWCPPGGDLEAYAKMTNALLLCLRGNPILYQGEELGLTQAEIAFEDLQDPEAIANWPLTLGRDGAR
TPMPWINDNSYAGFSEVKPWLPVGAGHALRAAMAQYGQPFSVLEFTRLVISLRSSSDILKFGSVSFPETQGDLLAIERRL
GEDRLLCLFNLGIKAVSVDVALPRFATTLLSSDGRLEGPENLPPFGVWIGTVGPHSD

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=515, Percent_Identity=32.8155339805825, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI65506891, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI61744479, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI61744475, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI61744483, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI61744481, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI61744477, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790687, Length=487, Percent_Identity=35.523613963039, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1786604, Length=494, Percent_Identity=22.2672064777328, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=375, Percent_Identity=25.8666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147709, Length=482, Percent_Identity=24.896265560166, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321731, Length=570, Percent_Identity=33.6842105263158, Blast_Score=270, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6322245, Length=558, Percent_Identity=34.0501792114695, Blast_Score=269, Evalue=7e-73,
Organism=Saccharomyces cerevisiae, GI6319776, Length=570, Percent_Identity=33.6842105263158, Blast_Score=269, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6321726, Length=559, Percent_Identity=32.5581395348837, Blast_Score=259, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6322241, Length=567, Percent_Identity=32.8042328042328, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322021, Length=567, Percent_Identity=32.8042328042328, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6324416, Length=573, Percent_Identity=33.3333333333333, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24586591, Length=536, Percent_Identity=36.7537313432836, Blast_Score=301, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24586597, Length=539, Percent_Identity=34.6938775510204, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24583745, Length=524, Percent_Identity=36.8320610687023, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24586589, Length=532, Percent_Identity=37.593984962406, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24586599, Length=527, Percent_Identity=34.5351043643264, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI221330053, Length=534, Percent_Identity=35.2059925093633, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24583749, Length=519, Percent_Identity=36.0308285163777, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24583747, Length=519, Percent_Identity=36.0308285163777, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24586587, Length=537, Percent_Identity=34.8230912476723, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24586593, Length=525, Percent_Identity=34.6666666666667, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI45549022, Length=527, Percent_Identity=32.6375711574953, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI281360393, Length=472, Percent_Identity=31.9915254237288, Blast_Score=216, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 60117; Mature: 59986

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPETQPWWRGAVIYQIYPRSYQDSNSDGVGDLPGITRRLDHIASLGVSAIWISPFFKSP
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHCH
MKDFGYDVSDYCDVDPAFGTLADFDTLMERARSLGLKVIIDQVYAHTSDAHAWFAESRAS
HHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
RANPKADWFVWRDAKPDGTPPNNWQSVFGGPAWTWDARRGQYFMHNFLSSQPQLNVHNPE
CCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCH
VQDALLSVAKFWLDRGVDGFRLDAINFAMFDPEFRDNPPWPAEGRTITRPFDLQHHIHNQ
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEECCCCCHHHHHCCC
SHPDIPVFMERVRALADTYGDIYTVAEVPGPDPLPEMRAFTSEGRLSSAYSFDFLYAKSL
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCC
SPRRVKASQMNWAGPLSEGWAAWAFSNHDAPRCISRWCPPGGDLEAYAKMTNALLLCLRG
CCCHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECC
NPILYQGEELGLTQAEIAFEDLQDPEAIANWPLTLGRDGARTPMPWINDNSYAGFSEVKP
CEEEEECHHCCCHHHHHHHHHCCCCHHHHCCCCEECCCCCCCCCCCCCCCCCCCHHHCCC
WLPVGAGHALRAAMAQYGQPFSVLEFTRLVISLRSSSDILKFGSVSFPETQGDLLAIERR
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHH
LGEDRLLCLFNLGIKAVSVDVALPRFATTLLSSDGRLEGPENLPPFGVWIGTVGPHSD
CCCCEEEEEEECCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SPETQPWWRGAVIYQIYPRSYQDSNSDGVGDLPGITRRLDHIASLGVSAIWISPFFKSP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECHHHHCH
MKDFGYDVSDYCDVDPAFGTLADFDTLMERARSLGLKVIIDQVYAHTSDAHAWFAESRAS
HHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
RANPKADWFVWRDAKPDGTPPNNWQSVFGGPAWTWDARRGQYFMHNFLSSQPQLNVHNPE
CCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCH
VQDALLSVAKFWLDRGVDGFRLDAINFAMFDPEFRDNPPWPAEGRTITRPFDLQHHIHNQ
HHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEECCCCCHHHHHCCC
SHPDIPVFMERVRALADTYGDIYTVAEVPGPDPLPEMRAFTSEGRLSSAYSFDFLYAKSL
CCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEEEEECCC
SPRRVKASQMNWAGPLSEGWAAWAFSNHDAPRCISRWCPPGGDLEAYAKMTNALLLCLRG
CCCHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECC
NPILYQGEELGLTQAEIAFEDLQDPEAIANWPLTLGRDGARTPMPWINDNSYAGFSEVKP
CEEEEECHHCCCHHHHHHHHHCCCCHHHHCCCCEECCCCCCCCCCCCCCCCCCCHHHCCC
WLPVGAGHALRAAMAQYGQPFSVLEFTRLVISLRSSSDILKFGSVSFPETQGDLLAIERR
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHH
LGEDRLLCLFNLGIKAVSVDVALPRFATTLLSSDGRLEGPENLPPFGVWIGTVGPHSD
CCCCEEEEEEECCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]